Abstract：
OBJECTIVE: The purpose of this prospective study was to evaluate the incidence and intensity of postoperative pain in oncological patients with infected teeth subjected to nonsurgical root canal treatment or retreatment.
METHODS: Teeth with apical periodontitis from healthy control patients and oncological patients (n = 70 per group) were root canal treated/retreated and evaluated for the development of postoperative pain. Patients from the two groups were matched for tooth type, gender, clinical manifestation of apical periodontitis, and intervention type. A visual analogue scale (VSA) was used to evaluate the incidence of postoperative pain at 24 h, 72 h, 7d, and 15d after chemomechanical procedures. Data were statistically analyzed for the incidence and intensity of postoperative pain in the two groups.
RESULTS: Preoperative pain occurred in 10% of the individuals and in all these cases pain showed a reduction in intensity or was absent after endodontic intervention at 24-h evaluation. The overall incidence of postoperative pain at 24 h was 14% in oncology patients and 30% in controls (p = 0.03). At 72 h, the respective corresponding figures were 4% and 8.5% (p > 0.05). At 7 and 15 days, all patients were asymptomatic, irrespective of the group.
CONCLUSIONS: No significant differences in postoperative pain were found between control and oncological patients. The low incidence of postoperative pain observed in both groups supports the routine use of nonsurgical root canal treatment/retreatment as valid options in oncological patients.
CONCLUSIONS: Oncological patients had no increased risk of postoperative pain in comparison with control patients.
METHODS: Teeth with apical periodontitis from healthy control patients and oncological patients (n = 70 per group) were root canal treated/retreated and evaluated for the development of postoperative pain. Patients from the two groups were matched for tooth type, gender, clinical manifestation of apical periodontitis, and intervention type. A visual analogue scale (VSA) was used to evaluate the incidence of postoperative pain at 24 h, 72 h, 7d, and 15d after chemomechanical procedures. Data were statistically analyzed for the incidence and intensity of postoperative pain in the two groups.
RESULTS: Preoperative pain occurred in 10% of the individuals and in all these cases pain showed a reduction in intensity or was absent after endodontic intervention at 24-h evaluation. The overall incidence of postoperative pain at 24 h was 14% in oncology patients and 30% in controls (p = 0.03). At 72 h, the respective corresponding figures were 4% and 8.5% (p > 0.05). At 7 and 15 days, all patients were asymptomatic, irrespective of the group.
CONCLUSIONS: No significant differences in postoperative pain were found between control and oncological patients. The low incidence of postoperative pain observed in both groups supports the routine use of nonsurgical root canal treatment/retreatment as valid options in oncological patients.
CONCLUSIONS: Oncological patients had no increased risk of postoperative pain in comparison with control patients.
摘要：
目的：这项前瞻性研究的目的是评估非手术根管治疗或再治疗的感染牙齿的肿瘤患者术后疼痛的发生率和强度。
方法：对健康对照患者和肿瘤患者（每组70例）的根尖周炎牙齿进行根管治疗/再治疗，并评估术后疼痛的发展。两组患者的牙齿类型相匹配，性别,根尖周炎的临床表现，干预类型。采用视觉模拟评分法(VSA)评估术后24h疼痛的发生率,72小时,7d,和15d后化学机械程序。对两组患者术后疼痛的发生率和强度进行统计学分析。
结果：术前疼痛发生在10％的个体中，在所有这些病例中，疼痛在24小时的牙髓干预后显示强度降低或消失。肿瘤患者术后24h疼痛的总发生率为14%，对照组为30%(p=0.03)。在72小时，相应的数字分别为4%和8.5%(p>0.05)。在7天和15天，所有患者均无症状,与集团无关。
结论：对照组和肿瘤患者术后疼痛无显著差异。在两组中观察到的术后疼痛发生率低，支持常规使用非手术根管治疗/再治疗作为肿瘤患者的有效选择。
结论：与对照组相比，肿瘤患者术后疼痛的风险没有增加。
方法：对健康对照患者和肿瘤患者（每组70例）的根尖周炎牙齿进行根管治疗/再治疗，并评估术后疼痛的发展。两组患者的牙齿类型相匹配，性别,根尖周炎的临床表现，干预类型。采用视觉模拟评分法(VSA)评估术后24h疼痛的发生率,72小时,7d,和15d后化学机械程序。对两组患者术后疼痛的发生率和强度进行统计学分析。
结果：术前疼痛发生在10％的个体中，在所有这些病例中，疼痛在24小时的牙髓干预后显示强度降低或消失。肿瘤患者术后24h疼痛的总发生率为14%，对照组为30%(p=0.03)。在72小时，相应的数字分别为4%和8.5%(p>0.05)。在7天和15天，所有患者均无症状,与集团无关。
结论：对照组和肿瘤患者术后疼痛无显著差异。在两组中观察到的术后疼痛发生率低，支持常规使用非手术根管治疗/再治疗作为肿瘤患者的有效选择。
结论：与对照组相比，肿瘤患者术后疼痛的风险没有增加。
