■这项研究的目的是描述一种罕见的透明细胞肾细胞癌(ccRCC)转移到翼状腋窝的病例。
一名54岁的妇女在过去的六周内由于右侧面部疼痛而被转诊至耳鼻喉科。
■ccRCC转移至翼上颌窝。
■在多学科团队评估后,患者接受免疫治疗(伊匹单抗+纳武单抗)治疗。
■18个月后,患者总体状况良好,颅底病变的大小显着减小。
■ccRCC向颅底和邻近部位的转移很少发生。最常见的是,这些病变的症状是头痛和复视的颅底转移和鼻出血的情况下,鼻窦受累,根据文献。当转移的完全切除是不可行的,可以使用肿瘤靶向治疗,如在所提出的情况下。建议进行多学科评估,以正确评估和管理这些患者。
UNASSIGNED: The aim of this study is to describe a rare
case of clear-cell renal cell carcinoma (ccRCC) metastasis to the pterygomaxillary fossa.
UNASSIGNED: A 54-year-old woman was referred to the Department of Otolaryngology due to right facial pain for the past six weeks.
UNASSIGNED: ccRCC metastasis to the pterygomaxillary fossa.
UNASSIGNED: The patient was treated by immunotherapy (Ipilimumab + Nivolumab) after multidisciplinary team evaluation.
UNASSIGNED: After 18 months, the patient is in good overall condition and the size of the skull base lesion has significantly reduced.
UNASSIGNED: ccRCC metastasis to the skull base and adjacent sites occur rarely. Most commonly, the presenting symptoms of these lesions are headache and diplopia for skull base metastases and epistaxis in
case of sinusal involvement, according to the literature. When total resection of the metastasis is not feasible, tumour-targeted therapy may be used, as in the presented
case. A multidisciplinary evaluation is recommended for the correct assessment and management of these patients.