Pulmonologists

肺科医师
  • 文章类型: Meta-Analysis
    冠状病毒病-19(COVID-19)增加了肺部和呼吸科本来就很重的工作量,因此,这可能会增加肺科医师或呼吸治疗师中职业倦怠的患病率。我们旨在通过荟萃分析进行系统评价,比较肺科医师或呼吸治疗师在COVID-19前后的倦怠差异。
    我们搜索了肺科医生,或者肺,或呼吸,和倦怠到2023年1月29日在六个数据库中。我们纳入了调查肺科医师或呼吸治疗师的研究,并报告了其中职业倦怠的患病率。偏倚的风险通过患病率研究工具进行评估。汇总了倦怠的总体患病率。
    总共确定了2859条记录,并将16项研究纳入最终分析。纳入的研究报告了3610名反应个体和2336名倦怠。合并的倦怠患病率为61.7%(95%置信区间(CI),48.6-73.2%;I2=96.3%)。COVID-19期间的合并倦怠患病率明显高于爆发前(68.4%vs.41.6%,p=.01)。荟萃回归结果显示,COVID-19覆盖率与职业倦怠的患病率显著相关(p=.04)。
    倦怠在肺科医师或呼吸治疗师中广泛流行,并且在COVID-19期间越来越多地感觉到倦怠。因此,需要采取干预措施来减少该专业的倦怠。关键信息冠状病毒病-19增加了肺和呼吸科本已繁重的工作量。职业倦怠在肺科医师或呼吸治疗师中广泛流行,并且在COVID-19期间越来越多地感觉到职业倦怠。
    The coronavirus disease-19 (COVID-19) increased the already heavy workload in the pulmonary and respiratory departments, which therefore possibly increased the prevalence of burnout among pulmonologists or respiratory therapists. We aimed to compare the differences in burnout among pulmonologists or respiratory therapists pre- and post-COVID-19 by doing a systematic review with meta-analysis.
    We searched pulmonologist, or pulmonary, or respiratory, and burnout up to 29 January 2023 in six databases. We included studies investigating pulmonologists or respiratory therapists and reporting the prevalence of burnout among them. The risk of bias was assessed by a tool for prevalence studies. The overall prevalence of burnout was pooled.
    A total of 2859 records were identified and 16 studies were included in the final analysis. The included studies reported 3610 responding individuals and 2336 burnouts. The pooled prevalence of burnout was 61.7% (95% confidence interval (CI), 48.6-73.2%; I2 = 96.3%). The pooled prevalence of burnout during COVID-19 was significantly higher than it was prior to the outbreak (68.4% vs. 41.6%, p = .01). The result of the meta-regression revealed that COVID-19 coverage was significantly associated with the prevalence of burnout (p = .04).
    Burnout was widely prevalent among pulmonologists or respiratory therapists and increasingly perceived during COVID-19. Therefore, interventions were needed to reduce burnout in this specialty.KEY MESSASGESThe coronavirus disease-19 increased the already heavy workload in the pulmonary and respiratory departments.Burnout was widely prevalent among pulmonologists or respiratory therapists and increasingly perceived during COVID-19.
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  • 文章类型: Journal Article
    气候变化对全球健康产生不利影响。越来越多,温度的变化,恶劣天气,空气质量下降,不断增长的粮食和清洁水供应不安全威胁着人类健康。预计到21世纪末,地球温度将上升至6.4°C,加剧威胁。公众和医疗保健专业人员,包括肺波学家,感知气候变化和空气污染的有害影响;他们支持减轻其影响的努力。事实上,有强有力的证据表明,过早的心肺死亡与通过呼吸系统吸入的空气污染暴露有关,它作为入口的门户。然而,在认识气候变化和空气污染对各种肺部疾病的影响方面,肺科医师几乎没有指导。
    结果:为了胜任教育和减轻患者的风险,肺科医师必须掌握气候变化和空气污染对特定肺部疾病影响的循证研究结果。我们的目标是为肺科医师提供背景和工具,以改善患者的健康并防止不良结果,尽管气候变化带来了威胁。
    结论:在这篇综述中,我们详述了气候变化和空气污染对多种肺部疾病影响的现有证据.知识可以为患者提供主动和个性化的预防策略,而不仅仅是被动地治疗疾病。
    Climate change adversely impacts global health. Increasingly, temperature variability, inclement weather, declining air quality, and growing food and clean water supply insecurities threaten human health. Earth\'s temperature is projected to increase up to 6.4 °C by the end of the 21st century, exacerbating the threat. Public and health care professionals, including pulmonologists, perceive the detrimental effects of climate change and air pollution and support efforts to mitigate its effects. In fact, evidence is strong that premature cardiopulmonary death is associated with air pollution exposure via inhalation through the respiratory system, which functions as a portal of entry. However, little guidance is available for pulmonologists in recognizing the effects of climate change and air pollution on the diverse range of pulmonary disorders. To educate and mitigate risk for patients competently, pulmonologists must be armed with evidence-based findings of the impact of climate change and air pollution on specific pulmonary diseases. Our goal is to provide pulmonologists with the background and tools to improve patients\' health and to prevent adverse outcomes despite climate change-imposed threats. In this review, we detail current evidence of climate change and air pollution impact on a diverse range of pulmonary disorders. Knowledge enables a proactive and individualized approach toward prevention strategies for patients, rather than merely treating ailments reactively.
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  • 文章类型: Journal Article
    在这次审查中,我们介绍了肺过度充气对心血管系统(CVS)的影响以及不同放气治疗方式的有益结果.我们讨论了长效支气管扩张剂药物的作用,医学和外科肺减容对CVS的表现。尽管有少量研究研究肺放气和CVS,心脏功能的短期改善得到明确证实.然而,更多研究,持续时间较长,需要验证肺部放气对CVS的这些显着的有益影响。运动过程中的动态过度充气可能是进一步研究肺过度充气和/或放气对CVS影响的研究模型。
    In this review, we present the effects of lung hyperinflation on the cardiovascular system (CVS) and the beneficial outcomes of different deflation treatment modalities. We discuss the effects of long-acting bronchodilator drugs, medical and surgical lung volume reduction on the performance of the CVS. Although there is a small number of studies investigating lung deflation and the CVS, the short-term improvement in heart function was clearly demonstrated. However, more studies, with longer duration, are needed to verify these significant beneficial effects of deflation of the lungs on the CVS. Dynamic hyperinflation during exercise could be a research model to investigate further the effects of lung hyperinflation and/or deflation on the CVS.
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  • 文章类型: Journal Article
    目的:成像是评估囊性纤维化(CF)肺病的重要非侵入性手段,这仍然是CF患者发病和死亡的主要原因。虽然新成像技术的发展彻底改变了临床实践,进步带来了诊断和监测的挑战。作者旨在总结这些挑战,并为临床医生和放射科医生提供有关影像学评估的循证建议。
    方法:召集了由来自意大利10个最大专家中心的21名CF专家组成的委员会,包括每个中心的放射科医生和肺科医生,总体目标是为CF的肺部成像制定清晰可行的建议。接受每一项建议声明需要至少80%的投票的先验门槛。
    结果:在对相关文献进行系统回顾之后,委员会召开会议评估167篇文章。在五次兰德会议之后,一个执行小组委员会制定了共识声明。整个共识委员会投票通过了28项主要声明。
    结论:有必要制定有关CF肺病患者影像学检查的适当时机和选择的国际指南;时机和选择取决于临床情况,病人的年龄,肺功能和治疗类型。尽管它无处不在,胸部X光片的使用仍然存在争议。计算机断层扫描和磁共振成像均应常规用于监测CF肺病。未来的研究应集中在计算机断层扫描和磁共振成像的成像协议协调上。人工智能成像分析的引入可能通过提供快速可靠的定量结果来评估疾病状态,从而进一步彻底改变临床实践。迄今为止,没有证据支持使用肺部超声监测CF肺病.
    OBJECTIVE: Imaging represents an important noninvasive means to assess cystic fibrosis (CF) lung disease, which remains the main cause of morbidity and mortality in CF patients. While the development of new imaging techniques has revolutionised clinical practice, advances have posed diagnostic and monitoring challenges. The authors aim to summarise these challenges and make evidence-based recommendations regarding imaging assessment for both clinicians and radiologists.
    METHODS: A committee of 21 experts in CF from the 10 largest specialist centres in Italy was convened, including a radiologist and a pulmonologist from each centre, with the overall aim of developing clear and actionable recommendations for lung imaging in CF. An a priori threshold of at least 80% of the votes was required for acceptance of each statement of recommendation.
    RESULTS: After a systematic review of the relevant literature, the committee convened to evaluate 167 articles. Following five RAND conferences, consensus statements were developed by an executive subcommittee. The entire consensus committee voted and approved 28 main statements.
    CONCLUSIONS: There is a need for international guidelines regarding the appropriate timing and selection of imaging modality for patients with CF lung disease; timing and selection depends upon the clinical scenario, the patient\'s age, lung function and type of treatment. Despite its ubiquity, the use of the chest radiograph remains controversial. Both computed tomography and magnetic resonance imaging should be routinely used to monitor CF lung disease. Future studies should focus on imaging protocol harmonisation both for computed tomography and for magnetic resonance imaging. The introduction of artificial intelligence imaging analysis may further revolutionise clinical practice by providing fast and reliable quantitative outcomes to assess disease status. To date, there is no evidence supporting the use of lung ultrasound to monitor CF lung disease.
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    文章类型: Journal Article
    Obstructive sleep apnea syndrome (OSAS) is a prevalent sleep disorder that leads to excessive daytime sleepiness and poor quality of life. OSAS is characterized by intermittent hypoxia and sleep fragmentation and is associated with increased risk of cardiovascular and neurocognitive disorders. The focus of our article is to discuss the approach to diagnosis and management.
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  • 文章类型: Journal Article
    肺癌是目前全球癌症相关死亡的主要原因,恶性胸腔积液,这种疾病晚期的指标,预示着预后不良。因此,准确诊断恶性胸腔积液至关重要。在过去的十年里,晚期非小细胞肺癌患者的预后有了明显改善,尤其是那些用靶向治疗和免疫疗法治疗的患者。使用胸膜液细胞学不仅可以提供诊断,而且可以帮助选择靶向治疗,特别是当获得组织学标本太困难时。在这个基于证据的审查中,我们探讨了非小细胞肺癌患者胸水细胞学的重要性,从诊断到在只有胸膜液时做出与治疗相关的决定。
    Lung cancer is the current leading cause of cancer-related deaths worldwide, and malignant pleural effusion, an indicator of the advanced stage of this disease, portends a poor prognosis. Thus, making an accurate diagnosis of malignant pleural effusion is of paramount importance. During the past decade, the prognosis of patients with advanced non-small cell lung cancer has improved substantially, especially in those treated with targeted therapy and immunotherapy. The use of pleural fluid cytology should not only provide diagnoses but also aid in the selection of targeted therapies, especially when obtaining a histologic specimen is too difficult. In this evidence-based review, we address the importance of pleural fluid cytology in non-small cell lung cancer patients, from making the diagnosis to making treatment-related decisions when only pleural fluid is available.
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  • 文章类型: Journal Article
    Introduction: The COVID-19 pandemic has provided global challenges to health-care facilities in ensuring the delivery of care to patients. Tremendous international collaboration has enabled the swift formulation of evidence-based guidelines that aim to clarify day-to-day issues faced by physicians and other health-care providers on the frontlines.Areas covered: In order to provide answers to the common questions and dilemmas faced by physicians and policymakers, especially those handling pulmonary manifestations of COVID-19, the authors made a list of pertinent clinical topics that were reviewed between 21st of August, 2020 to 30th of August, 2020 by the authors using online databases that included PubMed, EBSCO, and the Cochrane Library. Literature was reviewed and included based on relevance to the topics selected. The review was aimed to serve as a quick reference for addressing practical issues faced during patient care in the ongoing pandemic with a brief account of the management of COVID-19 patients as per international guidelines.Expert opinion: As more evidence continues to generate regarding the optimal methods of managing COVID-19 cases while caring for non-COVID patients concurrently, physicians will need to constantly reeducate themselves to keep pace with a rapidly evolving landscape of therapeutic options.
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  • 文章类型: Journal Article
    间质性肺病是一类异质性疾病,通常难以准确诊断。临床,实验室,射线照相,和组织学信息可能需要得出正确的诊断。多学科讨论已被证明在该患者组中是有用的。经支气管冷冻活检已成为获取组织样本的流行方法。在过去的十年里,有大量的研究评估可行性,安全,间质性肺病患者经支气管冷冻活检的诊断终点。数据继续挂载以支持其使用,这已反映在准则和专家小组报告中。患者选择,程序性能,和适当的标本处理是成功的关键因素。由具有间质性肺病专业知识的肺科医师协调的方法,介入肺科医师,胸病理学家是必不可少的。在这份基于证据的叙事审查中,我们从这三个不同的角度来讨论经支气管冷冻活检。此外,目前的文献用于解决9个常见的程序问题.
    Interstitial lung diseases are a heterogenous group of disorders that are often difficult to diagnose precisely. Clinical, laboratory, radiographic, and histologic information may be needed to arrive at the correct diagnosis. The multidisciplinary discussion has been proven to be useful in this patient group. Transbronchial cryobiopsy has become a popular method for obtaining tissue samples. Over the course of the last decade, there has been a significant amount of research assessing the feasibility, safety, and diagnostic endpoints of transbronchial cryobiopsy in patients with interstitial lung disease. Data continues to mount to support its use, which has been reflected in guidelines and expert panel reports. Patient selection, procedural performance, and appropriate specimen handling are critical factors for success. A coordinated approach by pulmonologists with expertise in interstitial lung diseases, interventional pulmonologists, and thoracic pathologists is essential. In this evidence-based narrative review, we address transbronchial cryobiopsies from these three distinct perspectives. In addition, the current literature was used to address nine common procedural questions.
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    文章类型: Journal Article
    Whether working in intensive care unit or not as nephrologists we are all facing complicated cases with different sign and symptoms. Among them is a category of patients presenting with concomitant respiratory and kidney failure called pulmonary renal syndrome, which needs mutual connection between nephrologist and pulmonologist closely for the best decision-making. Although this is not a common entity, still associated with high rate of morbidity and mortality involving diffuse alveolar hemorrhage and glomerulonephritis. Understanding the updates in the field of management would benefit both the patients and caregivers providing clear answers to present obstacles.
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  • 文章类型: Case Reports
    Acid sphingomyelinase deficiency (ASMD), also called Niemann-Pick disease, is a storage disorder with pulmonary involvement but few respiratory symptoms in adults. However, the disease may evolve towards clinically relevant respiratory symptoms with referral to the pulmonologist for management and care. Based on two case reports illustrating respiratory impairment, the aim of this work was to review clinical features, diagnosis, respiratory prognostic and therapeutics for the pulmonologist. Overall, storage disorder should be suspected in the presence of hepatosplenomegaly and interstitial lung disease. Concomitant thrombopenia or hyperlipidemia should also draw attention. Following recent consensus guidelines, diagnosis is based on enzyme assay for ASM activity in blood, with subsequent gene sequencing once the biochemical diagnosis has been confirmed. Disease is slowly progressive and the main causes of death are respiratory and liver failure. Presence of emphysema lesions or worsening of respiratory symptoms should call for the intensification of treatment. Though enzyme replacement therapy is a promising way of development, lung transplantation might be considered for these patients in the absence of contraindication.
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