新生儿先天性心脏病(CHD)是最常见的先天性异常。作为民生实事,对中国东部11个城市的潜在CHD儿童进行了心脏超声检查.在这项研究中,我们旨在记录冠心病的出生患病率及其社会经济和地理分布,这一公共卫生政策的支持。在这项研究中,根据超声心动图诊断冠心病。地理和社会经济因素由《国民经济和社会发展统计公报》(SBNESD)确定。纳入了2019年1月至12月在中国东部11个城市的先天性心脏病网络平台(NPCHD)的51857名新生儿。CHD的总出生患病率为每1000名婴儿5.79。对低收入地区的研究,山区,医疗机构床位水平较低的地区,与高收入城市相比,具有高资质的医务人员报告的CHD出生患病率明显高于高收入城市,平坦的区域,医疗机构床位水平较高的地区,和低资格的医务人员。ASD,VSD,PDA,PS,TOF,房室间隔缺损,主动脉缩窄,TAPVD,TGA和肺动脉闭锁是最常见的亚型。ASD,VSD,PDA,PS,房室间隔缺损,主动脉缩窄和肺动脉闭锁显示女性优势,而TOF,TGA和TAPVD显示男性优势。我们的研究表明,在对怀疑患有CHD阳性的新生儿进行心脏超声检查后,CHD的患病率相对现实。不同地理区域的显著差异,收入水平,并观察到卫生服务的获取。在未来,全人群心脏超声筛查,前瞻性出生缺陷登记处,需要覆盖整个东部甚至中国的系统医学随访计划来确定确切的出生患病率。
Neonatal congenital heart disease (CHD) is the most common congenital anomaly. As a practical matter of people\'s livelihood, cardiac ultrasonography was performed on potential CHD children in 11 cities eastern China. In this
study, we aimed to document the birth prevalence of CHD and its socioeconomic and geographical distribution, as supported by this public health policy. In this
study, the diagnosis of CHD was made based on echocardiography. Geographical and socioeconomic factors were determined by the Statistical Bulletin on National Economic and Social Development (SBNESD). 51857 newborns from the Network Platform for Congenital Heart Disease (NPCHD) from January to December 2019 in 11 cities eastern China were included. The total birth prevalence of CHD was 5.79 per 1000 births. The
study on the low-income areas, mountainous areas, areas with low medical institution bed level, and with high qualification of medical personnel reported a signifcantly higher birth prevalence of CHD compared with high-income cities, flat areas, areas with high medical institution bed level, and with low qualification of medical personnel. ASD, VSD, PDA, PS, TOF, atrioventricular septal defect, coarctation of the aorta, TAPVD, TGA and pulmonary atresia are the most frequent subtypes. ASD, VSD, PDA, PS, atrioventricular septal defect, coarctation of the aorta and pulmonary atresia showed a female preponderance, while TOF, TGA and TAPVD showed a male preponderance. Our
study gives a relatively realistic prevalence of CHD after cardiac ultrasound examination of newborns suspected positive with CHD. Significant differences across geographical regions, income levels, and health service access were observed. In the future, population-wide cardiac ultrasound screening, prospective birth defect registries, and systematic medical follow-up programs covering the entire eastern or even China are needed to determine the exact birth prevalence.