关键词: Atresia Catheterization Congenital Heart disease Infant Valvuloplasty Ventricular interdependence

Mesh : Infant Infant, Newborn Child Humans Male Female Retrospective Studies Pulmonary Atresia Heart Ventricles / diagnostic imaging Heart Defects, Congenital Pulmonary Valve Insufficiency Treatment Outcome Pulmonary Valve Stenosis / diagnostic imaging Cardiac Catheterization / methods Cardiomyopathies Echocardiography Ventricular Dysfunction, Left / diagnostic imaging

来  源:   DOI:10.7717/peerj.14056   PDF(Pubmed)

Abstract:
The aim of this study is to identify echocardiographic predictors of transient left ventricle dysfunction after pulmonary valve balloon dilatation (PVBD), in neonates with pulmonary valve stenosis (PVS) and atresia with intact septum (PAIVS) at birth.
The study includes patients admitted at the Bambino Gesù Children Hospital from January 2012 to January 2017. Clinical, echocardiographic and cardiac catheterization data before and after PVBD were retrospectively analyzed.
Twenty-nine infants were included in the study (21 male and eight female). The median age was 5.8 ± 7.1 days. Eight patients developed transient LV dysfunction (three PAIVS and five PVS) and comparing data before and after the procedure, there was no difference in right ventricle geometrical and functional parameters except for evidence of at least moderate pulmonary valve regurgitation after PVBD.
Moderate to severe degree pulmonary valve regurgitation was significant associated to LV dysfunction (p < 0.05) in PVS and PAIVS patients.
摘要:
UNASSIGNED:本研究的目的是确定肺动脉瓣球囊扩张(PVBD)后短暂性左心室功能障碍的超声心动图预测因子,出生时患有肺动脉瓣狭窄(PVS)和隔膜完整闭锁(PAIVS)的新生儿。
UNASSIGNED:该研究包括2012年1月至2017年1月在班比诺·格苏儿童医院住院的患者。临床,回顾性分析PVBD前后的超声心动图和心导管检查资料。
未经评估:29名婴儿被纳入研究(21名男性和8名女性)。中位年龄为5.8±7.1天。8例患者出现了短暂性LV功能障碍(3例PAIVS和5例PVS),并比较了手术前后的数据,右心室几何参数和功能参数无差异,但有证据表明PVBD后肺动脉瓣反流至少中度.
未经证实:在PVS和PAIVS患者中,中度至重度肺动脉瓣反流与LV功能障碍显著相关(p<0.05)。
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