2005年5月，一名49岁的男子被诊断出患有小细胞肺癌。化疗开始于60毫克/天的顺铂静脉滴注（从第1天到第3天），2mg盐酸托泊替康（TP）静脉滴注（从第1天到第4天），和中药艾迪注射液抗肿瘤。四个周期后，他在2005年10月接受了56Gy/28分的适形放疗.2006年4月，在右锁骨上区域发现了一个肿块。因此,他接受了另一个疗程的放射治疗。视野包括右锁骨上区域，辐射剂量为50Gy/25分。完成放化疗后，患者达到完全缓解。随后，患者接受预防性颅骨照射(PCI).直到2012年4月，他一直被定期跟踪。自从SCLC诊断以来，他已经接受中医治疗七年了。2012年4月，患者再次抱怨咳嗽。随后，患者接受了5个周期的依托泊苷卡铂方案.进行计算机断层扫描（CT）扫描以进行检查，没有明显变化。该患者接受了伊立替康顺铂3次二线化疗。然而,该患者的症状和CT没有显着改善。我们将化疗方案改为TP（托泊替康1.2mg静脉滴注，第1天至第5天；卡铂100毫克静脉滴注，一至五天）。经过两个TP方案，患者于2013年3月3日在睡梦中死亡.在这种情况下,标准化的序贯化疗和放疗，PCI,TCM,良好的依从性可能有助于患者的生存期更长。
A 49-year-old man was diagnosed with small cell lung cancer in May 2005. Chemotherapy was started with 60 mg/day cisplatin iv drip (from days one to three), 2 mg topotecan (TP) hydrochloride iv drip (from days one to four), and traditional Chinese medicine (TCM) AiDi injection for anti-tumor. After four cycles, he underwent conformal radiotherapy with 56Gy/28 fractions in October 2005. In April 2006, a mass on the right supraclavicular area was found. Therefore, he underwent another course of radiotherapy. The fields included the right supraclavicular area and the radiation dose was 50Gy/25 fractions. After completion of chemoradiotherapy, the patient achieved complete remission. Subsequently, the patient received prophylactic cranial irradiation (PCI). Until April of 2012, he had been followed up regularly. Since the SCLC diagnosis, he had received TCM for seven years. In April 2012, the patient complained of coughing again. Subsequently, the patient was given five cycles of an etoposide carboplatin regimen. A computed tomography (CT) scan was performed for review, which showed no obvious change. The patient underwent a second-line chemotherapy irinotecan cisplatin three times. However, the symptoms and CT of this patient showed no significant improvement. We changed the chemotherapy regimen to TP (topotecan 1.2 mg iv drip, days one to five; carboplatin 100 mg iv drip, days one to five). After two TP regimens, the patient died in his sleep on 3 March 2013. In this
case, the standardized sequential chemotherapy and radiotherapy treatment, PCI, TCM, and good compliance may have contributed to the patient\'s longer survival.
