自成立以来,原代视网膜培养物已经成为一种体外工具,用于模拟视网膜的体内环境,以进行发育和疾病的生物学研究。与体内模型相比,它们提供了简单且受控的实验方法。在这篇综述中,我们强调了原发性视网膜培养模型的优缺点,以及分散的视网膜细胞培养物的特征。
Since its inception, primary retinal cultures have been an in vitro tool for modeling the in vivo environment of the retina for biological studies on development and disease. They offer simple and controlled experimental approaches when compared to in vivo models. In this review we highlight the strengths and weaknesses of primary retinal culture models, and the features of dispersed retinal cell cultures.