未经批准:注射毒品的人感染艾滋病毒的风险很大,特别是注射毒品的妇女(WWID)。HIV暴露前预防(PrEP),一种高效的艾滋病毒预防药物,在WWID中进行了罕见的研究,我们的目标是在该人群的整个PrEP连续护理中综合现有知识。
UNASSIGNED:我们在三个电子数据库中系统地搜索了同行评审的文献,会议摘要来自三个主要的艾滋病毒会议,和相关来源的灰色文献。资格标准包括定量,定性或混合方法研究,主要数据收集报告WWID中与PrEP相关的发现,并在2012年至2021年之间以英文或西班牙文出版。最初的搜索确定了2,809条引文,包括32个。提取了有关研究特征和PrEP护理连续性的数据,然后对数据进行叙述性回顾分析.
UASSIGNED:我们的搜索确定了2,809项研究;32项符合资格要求。总的来说,意识,知识,在WWID中,PrEP的使用率很低,虽然可接受性很高。无家可归,性暴力,药物使用的不可预测性,以及对医疗保健系统的访问对PrEP的使用和依从性提出了挑战。WWID愿意与其他WWID共享有关PrEP的信息,尤其是那些感染艾滋病毒的高危人群,比如性工作者。
UNASSIGNED:为了提高PrEP的使用和WWID在护理中的参与度,PrEP服务可以纳入对性别敏感的减少伤害和药物治疗服务。基于同行的干预措施可用于提高该人群对PrEP的认识和知识。需要进一步研究跨性别WWID以及所有WWID中的PrEP保留和依从性。
UNASSIGNED: People who inject drugs have a substantial risk for HIV infection, especially women who inject drugs (WWID). HIV pre-exposure prophylaxis (PrEP), a highly-effective HIV prevention drug, is uncommonly studied among WWID, and we aimed to synthesize existing knowledge across the full PrEP continuum of care in this population.
UNASSIGNED: We systematically searched for peer-reviewed literature in three electronic databases, conference abstracts from three major HIV conferences, and gray literature from relevant sources.Eligibility criteria included quantitative, qualitative or mixed-methods studies with primary data collection reporting a PrEP-related finding among WWID, and published in English or Spanish between 2012 and 2021. The initial search identified 2,809 citations, and 32 were included. Data on study characteristics and PrEP continuum of care were extracted, then data were analyzed in a narrative
review.
UNASSIGNED: Our search identified 2,809 studies; 32 met eligibility requirements. Overall, awareness, knowledge, and use of PrEP was low among WWID, although acceptability was high. Homelessness, sexual violence, unpredictability of drug use, and access to the healthcare system challenged PrEP usage and adherence. WWID were willing to share information on PrEP with other WWID, especially those at high-risk of HIV, such as sex workers.
UNASSIGNED: To improve PrEP usage and engagement in care among WWID, PrEP services could be integrated within gender-responsive harm reduction and drug treatment services. Peer-based interventions can be used to improve awareness and knowledge of PrEP within this population. Further studies are needed on transgender WWID as well as PrEP retention and adherence among all WWID.