Potential factors

潜在因素
  • 文章类型: Journal Article
    间接牙髓疗法(IPT)是深龋的常用保守治疗方法。然而,IPT预后的潜在危险因素尚未得到很好的研究.这项研究回顾性调查了IPT治疗原发性磨牙伴深龋的成功率以及可能影响两年成功率的因素。这项研究共包括202名儿童(106名男孩和96名女孩)的303个初级磨牙。通过临床和影像学检查,这些原发性磨牙被确定为有深龋,并接受IPT治疗。随访2年后,对影响IPT成功率的因素进行分析。结果表明,两年IPT成功率为86%(262/303)。有和没有不锈钢冠的初级磨牙的成功率为96%(120/125)和80%(142/178),分别。用不锈钢牙冠处理的原发性磨牙显示出明显较低的失败风险(风险比(HR)=0.18,95%置信区间(CI):(0.10,0.34),p=0.01)。其他因素无显著差异,包括性别(男性vs.female),年龄(学龄前vs.学龄),合作水平(弗兰克尔2vs.3或4个刻度),弓型(上颌vs.下颌),牙齿类型(第一vs.第二伯磨牙),或纸浆封盖材料(氢氧化钙与玻璃离聚物水泥)。IPT是一种有效的,原发性磨牙伴深龋的保守治疗方式。不锈钢冠可以显著提高IPT成功率。
    Indirect pulp therapy (IPT) is a common conservative treatment for deep dental caries. However, the potential risk factors for the prognosis of IPT have not been well studied. This study retrospectively investigated the success rate of IPT in treating primary molars with deep caries and the factors potentially affecting the two-year success rate. A total of 303 primary molars in 202 children (106 boys and 96 girls) were included in this study. These primary molars were identified as having deep caries by clinical and radiographic examinations and were treated with IPT. The factors potentially affecting the IPT success rate were analyzed after two years of follow-up. The results indicated that the two-year IPT success rate was 86% (262/303). The success rate of primary molars with and without stainless steel crowns was 96% (120/125) and 80% (142/178), respectively. Primary molars treated with stainless steel crowns showed a significantly lower risk of failure (hazard ratio (HR) = 0.18, 95% confidence interval (CI): (0.10, 0.34), p = 0.01). There were no significant differences in other factors, including gender (male vs. female), age (preschool vs. school age), cooperation level (Frankl 2 vs. 3 or 4 scales), arch type (maxillary vs. mandibular), tooth type (first vs. second primary molar), or pulp capping material (calcium hydroxide vs. glass ionomer cement). IPT is an effective, conservative treatment modality for primary molars with deep caries. Stainless steel crowns could significantly improve the IPT success rate.
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  • 文章类型: Journal Article
    认知损害作为中风后患者的并发症在全世界具有很高的患病率。然而,很少有研究关注老年卒中幸存者,并探讨他们的卒中后认知障碍(PSCI)患病率和影响因素.本研究旨在评估湖南省脑卒中患者的认知状况,并确定与PSCI相关的潜在危险因素,以提前识别中老年人群,促进健康老龄化。
    这项横断面研究于8月至12月进行,2021年。随机选择来自6家三级医院的520例脑卒中幸存者。这些信息是使用一般问卷收集的,Barthel指数评定量表和迷你精神状态检查(MMSE)。分析是基于描述性统计,卡方检验和显著变量纳入多变量逻辑回归。这项横断面研究的报告遵循STROBE检查表。
    根据MMSE评分结果,共对195名老年人(40.37%)进行了认知障碍筛查。PSCI组患者的70岁或以上人群比例较高(35.90%vs.24.65%,p<0.001)。老年人卒中后认知障碍的潜在危险因素为70-79岁(OR=3.973,95%CI,2.346-6.729,p<0.001),年龄在80岁或以上(OR=3.590,95%CI,1.373-9.387,p=0.009),受教育程度低(OR=9.183,95%CI,5.341-15.789,p<0.001),有高血压(OR=1.756,95%CI,1.121-2.753,p=0.014),并有优势半球病变(OR=1.880,95%CI,1.193-2.962,p<0.001)。
    中国老年人PSCI患病率较高,特别是那些80岁或以上的人。我们研究中确定的因素可以帮助早期识别处于危险中的老年人,制定个性化的管理计划,促进健康衰老。
    Cognitive impairment as a complication in post-stroke patients has high prevalence throughout the world. However, few studies have focused on the older adult stroke survivors and explored their prevalence and factors of post-stroke cognitive impairment (PSCI). The study aims to evaluate the cognitive status of stroke patients in Hunan Province, China and to determine the potential risk factors associated with PSCI in order to identify the older adult population in advance and promote healthy aging.
    This cross-sectional study was carried out from August to December, 2021. A total of 520 stroke survivors from 6 tertiary hospitals were randomly selected. The information was collected using the general questionnaire, the Barthel Index Rating Scale and the Mini-mental State Examination (MMSE). Analysis was based on descriptive statistics, chi-square test and the significant variables were included in multivariate logistic regression. The reporting of this cross-sectional study followed the STROBE checklist.
    A total of 195 older adults (40.37%) were screened for cognitive impairment based on the results of the MMSE score. Patients in the PSCI group had a higher proportion of individuals aged 70 or older (35.90% vs. 24.65%, p<0.001). The potential risk factors for post-stroke cognitive impairment in older adults were being aged between 70 and 79 years old (OR = 3.973, 95% CI, 2.346-6.729, p<0.001), being aged 80 years or older (OR = 3.590, 95% CI, 1.373-9.387, p = 0.009), having a low level of education (OR = 9.183, 95% CI, 5.341-15.789, p<0.001), having hypertension (OR = 1.756, 95% CI, 1.121-2.753, p = 0.014), and having a dominant hemisphere lesion (OR = 1.880, 95% CI, 1.193-2.962, p<0.001).
    The prevalence of PSCI was high among Chinese older adults, particularly those aged 80 years or older. The factors identified in our study could assist in the early identification of older adults at risk, develop personalized management plans, and promote healthy aging.
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  • 文章类型: Journal Article
    UNASSIGNED: In 2021, National Health Commission of the People\'s Republic of Chinese issued a document that no longer recommended the routine skin test for cephalosporin (RSTC). However, there is still resistance to the cancellation of RSTC in a primary hospital. The study aimed to explore the potential factors for hindering the abolition of the RSTC in a county-level hospital based on the PRECEDE model.
    UNASSIGNED: The cross-sectional study was conducted on healthcare workers in the Pidu District People\'s Hospital, Chengdu, by online questionnaire from September 10 to September 25 in the 2021.The PRECEDE model was used to divide the potential factors of healthcare professionals in hindering the abolition of the RSTC into predisposing factors, enabling factors and reinforcing factors. Data were analyzed by ANOVA, Chi-square test, multiple linear and multiple logistic regression analysis.
    UNASSIGNED: We collected 605 respondents\' valid questionnaires. 254 healthcare professionals were against cancellation of the RSTC, accounting for 41.98%. Multiple linear regression analysis showed that working for 6~10 years (β = 1.953, P = 0.024), medium (β = 1.995, P = 0.030) or senior (β = 4.003, P = 0.007) professional qualification, pharmacists (β = 3.830, P = 0.013) and working in surgical department (β= 4.462, P < 0.001) were significantly associated with higher score of predisposing factors, enabling factors, and reinforcing factors on abolition of RSTC. Furthermore, multiple logistic regression analysis showed that pharmacists (OR=3.113, 95% CI: 1.341-7.223, P=0.030), medium professional qualification (OR=1.272, 95% CI: 0.702-2.302, P=0.008), scores of predisposing factors (OR=1.335, 95% CI: 1.033-1.726, P=0.009), and scores of enabling factors (OR=1.208, 95% CI: 1.109-1.315, P<0.001) were independently associated with the positive anticipated behavior on the abolition of RSTC. While nurses (OR=0.516, 95% CI: 0.284-0.938, P<0.001) were independently associated with anticipated negative behavior.
    UNASSIGNED: Pharmacists, medium professional qualification, and healthcare professionals with higher scores of predisposing and enabling factors were more likely to have a positive anticipated behavior on the abolition of RSTC, while nurses did not.
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  • 文章类型: Journal Article
    In China, cognitive impairment has become a huge challenge owing to the rapid aging process. We investigate cognitive health expectancy and potential factors leading to inequalities of cognitive health for Chinese older people.
    The study included 19 943 participants aged 65 to 95 at the first observation in Chinese Longitudinal Healthy Longevity Survey collected during 2002-2014. Cognitive impairment was categorized into none, mild, and severe by the score of cMMSE. Multistate models based on continuous-time Markov process were applied to calculate cognitive health expectancies and estimate hazard ratio from no impairment to impairment for potential factors.
    Urban women and men aged 65 were expected to spend 31.18% and 19.82% of their remaining 17.46 and 15.45 years with cognitive impairment; meanwhile, rural women and men aged 65 were expected to spend 35.31% and 21.39% of their remaining 16.73 and 14.87 years with cognitive impairment. Women achieving lower educational attainment (HR1-6 years  = 0.78, 95% CI, 0.71-0.87; HR7+ years  = 0.59, 95% CI, 0.49-0.70) than men and rural residents having less access to medical service (HR = 0.79, 95% CI, 0.68-0.92) and doing less regular exercise (HR = 0.87, 95% CI, 0.80-0.96) than urban people caused the differences of cognitive health for genders and regions.
    Women and rural people experience less cognitive health expectancies compared with their counterparts, respectively. Chinese government should pay more attention to rural women and make efforts to reduce the inequalities of cognitive health by increasing opportunities of education for women and improving access to medical service and healthy lifestyle for rural people.
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