背景:怀孕期间的疟疾可导致孕产妇和围产期的不良反应。尽管采取了预防措施,最近的研究表明,怀孕期间的疟疾仍然是一个威胁健康的问题,特别是在撒哈拉以南非洲国家。本研究旨在确定苏丹中部Rabak医院胎盘疟疾的患病率和相关因素。
方法:一项横断面研究于2021年9月至10月进行。包括在苏丹中部Rabak妇产医院分娩的孕妇。问卷用于收集产科和社会人口统计信息。使用母体制备疟疾血膜,胎盘,和脐带血,并进行了胎盘组织学检查。进行逻辑回归分析。
结果:对于208名女性,年龄和胎次的中位数(四分位数范围)分别为25(21.0-30.0)岁和2(1-4),分别。25名(12.0%)妇女使用过杀虫剂处理过的蚊帐。活动性感染,慢性活动性感染,和过去的慢性感染在四个(1.9%)中被检测到,五个(2.4%),和35个(16.8%)胎盘,分别。一百六十四个(78.8%)胎盘没有感染迹象。Logistic回归分析显示,没有一个被检查的因素(年龄,奇偶校验,教育,产前保健水平,使用杀虫剂处理过的蚊帐,和血型)与胎盘疟疾有关。
结论:疟疾影响20%的孕妇,不管他们的年龄和平价。因此,应鼓励在这方面采取预防措施。
BACKGROUND: Malaria during pregnancy can lead to maternal and perinatal adverse effects. Despite the preventive measures, recent research has shown that malaria during pregnancy is still a threatening health problem, especially in Sub-Saharan African countries. The current study was conducted to determine the prevalence of and factors associated with placental malaria in Rabak Hospital in central Sudan.
METHODS: A cross-sectional study was conducted from September to October 2021. Pregnant women who delivered at the Rabak Maternity Hospital in Central Sudan were included. A questionnaire was used to gather both obstetric and socio-demographic information. Blood films for malaria were prepared using the maternal, placental, and cord blood, and a placental histology was performed. A logistic regression analysis was performed.
RESULTS: For the 208 women, the medians (interquartile range) of their age and parity were 25 (21.0 ‒30.0) years and 2 (1‒4), respectively. Twenty-five (12.0%) of the women had used insecticide-treated nets. Active infection, active-chronic infection, and past-chronic infection were detected in four (1.9%), five (2.4%), and 35 (16.8%) placentas, respectively. One hundred and sixty-four (78.8%) placentas showed no signs of infection. Logistic regression analysis showed that none of the examined factors (age, parity, education, antenatal care level, use of insecticide-treated nets, and blood group) was associated with placental malaria.
CONCLUSIONS: Malaria affects 20% of pregnant women, regardless of their age and parity. Preventative measures should therefore be encouraged in this area.