Physicochemical properties

物理化学性质
  • 文章类型: Journal Article
    膳食纤维(DF)被认为是有益于人类健康的干预饮食。高DF摄入量有效降低三大慢性病的发病率,2型糖尿病(T2DM),心血管疾病(CVD),结直肠癌(CRC)。DF的健康益处与其理化性质密切相关,在人体消化和肠道健康中具有重要的积极作用。然而,将DF与疾病联系起来的机制尚不清楚。基因组学的发展,代谢组学,和免疫学,动物模型和临床试验的强大结合,有助于更好地理解DF和疾病之间的关系。越来越多的证据表明,DF的物理存在和DF-微生物群相互作用是控制DF在慢性病中作用机制的关键参数。因此,这篇综述讨论了DF调节T2DM的潜在机制,CVD,CRC,从而为更有效地利用DF干预慢性病提供理论依据。
    Dietary fiber (DF) is considered an interventional diet beneficial for human health. High DF intake effectively reduces the incidence of three major chronic diseases, type 2 diabetes (T2DM), cardiovascular disease (CVD), and colorectal cancer (CRC). The health benefits of DF are closely related to their physicochemical properties with major positive roles in human digestion and intestinal health. However, mechanisms linking DF with diseases remain unclear. The development of genomics, metabolomics, and immunology, and the powerful combination of animal models and clinical trials, have facilitated a better understanding of the relationships between DF and diseases. Accumulating evidence suggests that the physical existence of DF and DF-microbiota interaction are the key parameters controlling the action mechanisms of DF in chronic diseases. Therefore, this review discusses the potential mechanism of DF modulating T2DM, CVD, and CRC, therefore providing a theoretical basis for more effective use of DF to intervene in chronic diseases.
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  • 文章类型: Journal Article
    天然橡胶(NR)及其衍生物因其独特的性能和广泛的应用而在各个行业中发挥着不可或缺的作用。然而,NR的广泛使用面临着固有的挑战,如有限的机械强度,耐热性和耐有机溶剂性差,导电性差,与其他材料的兼容性低,促使研究人员探索提高其性能。修饰的NRs(MNRs)如环化,脱蛋白,氯化,环氧化,或接枝NR与NR相比表现出一些增强的优点。然而,各种策略,比如混合,硫化,交联,嫁接,塑化,钢筋,和纳米结构,克服了大多数缺点。这篇综述全面研究了这些挑战,并深入研究了用于增强NR及其衍生物的性能和扩展应用的改性策略。此外,这篇评论探讨了NR行业的未来愿景,强调整合先进的改性技术,采用可持续的做法,推广循环经济原则。通过阐明内在的挑战,概述有效的修改策略,设想未来的轨迹,这项审查为寻求导航和促进NR部门可持续发展的利益相关者提供了宝贵的见解。
    Natural rubber (NR) and its derivatives play indispensable roles in various industries due to their unique properties and versatile applications. However, the widespread utilization of NR faces intrinsic challenges such as limited mechanical strength, poor resistance to heat and organic solvent, poor electrical conductivity, and low compatibility with other materials, prompting researchers to explore enhancing its performance. Modified NRs (MNRs) like cyclization, deproteinization, chlorination, epoxidation, or grafting NR demonstrated a few enhanced merits compared to NR. However, various strategies, such as blending, vulcanization, crosslinking, grafting, plasticization, reinforcement, and nanostructuring, overcame most drawbacks. This review comprehensively examines these challenges and delves into the modification strategies employed to enhance the properties and expand the applications of NR and its derivatives. Furthermore, the review explores future visions for the NR industry, emphasizing integrating advanced modification techniques, adopting sustainable practices, and promoting circular economy principles. By elucidating the inherent challenges, outlining effective modification strategies, and envisioning future trajectories, this review provides valuable insights for stakeholders seeking to navigate and contribute to the sustainable development of the NR sector.
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  • 文章类型: Journal Article
    长期以来,人们一直在研究天然来源的生物活性化合物用于预防和治疗人类疾病。苦参酮G(SFG),一种天然存在于几种苦豆科植物物种中的lavandulyl黄酮,属于在当代研究中引起极大兴趣的戊烯化类黄酮。天然分子表现出广泛的药理学性质并显示出显著的功效。其有效抑制一系列恶性肿瘤细胞的能力,比如白血病,乳腺癌,肺癌,归因于它的多目标,多途径,和多方面的行动机制。同时,它还可以通过介导炎症介质和分子途径缓解各种炎症疾病。此外,它有能力对抗抗生素耐药性,表现出与多种抗生素的协同抗菌性能,预防和治疗各种农业害虫。理论上,它可以为人类健康带来益处,并具有潜在的药物价值。然而,水溶性差和靶向不足的缺点不容忽视。为了全面评估当前对SFG的研究,利用其结构优势和药理活性,克服其生物利用度低的限制,加速其发展成为一种新的治疗药物,更好地为诊所服务,本文对SFG的研究现状进行了全面回顾。讨论包括对结构特性的分析,物理化学性质,生物利用度,药理活性,和SFG的构效关系,目标是为该领域未来的研究工作提供有价值的见解和指导。
    Bioactive compounds derived from natural sources have long been investigated for the prevention and treatment of human diseases. Sophoraflavanone G (SFG), a lavandulyl flavanone naturally occurring in several Sophora plant species, belongs to the group of prenylated flavonoids that have garnered significant interest in contemporary research. The natural molecule exhibits a wide range of pharmacological properties and shows remarkable efficacy. Its ability to effectively suppress a range of malignant tumor cells, such as leukemia, breast cancer, and lung cancer, is attributed to its multi-target, multi-pathway, and multi-faceted mechanisms of action. Simultaneously, it can also alleviate various inflammatory diseases by mediating inflammatory mediators and molecular pathways. Furthermore, it has the capability to combat antibiotic resistance, exhibit synergistic antibacterial properties with diverse antibiotics, and prevent and treat various agricultural pests. Theoretically, it can bring benefits to human health and has potential value as a drug. Nevertheless, the drawbacks of poor water solubility and inadequate targeting cannot be overlooked. To comprehensively assess the current research on SFG, leverage its structural advantages and pharmacological activity, overcome its low bioavailability limitations, expedite its progression into a novel therapeutic drug, and better serve the clinic, this article presents a overall retrospect of the current research status of SFG. The discussion includes an analysis of the structural characteristics, physicochemical properties, bioavailability, pharmacological activities, and structure-activity relationships of SFG, with the goal of offering valuable insights and guidance for future research endeavors in this field.
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  • 文章类型: Journal Article
    膳食纤维来自广泛的来源并且具有多种制备方法(包括提取和改性)。不同的膳食纤维的结构特征造成的来源,提取和改性方法直接影响其理化性质和功能活性。结构和理化性质与功能活性的关系是实现膳食纤维结构的定向转化和准确调控其特定性质和活性不可或缺的基础理论。在本文中,自从简要概述了膳食纤维的结构特征,结构特征对各种物理化学性质的影响(水合,电气,热,流变学,乳化性能,和持油能力,阳离子交换能力)和功能活动(低血糖,降血脂,抗氧化剂,着重回顾了研究人员在过去五年中探索的膳食纤维的益生元和有害物质吸附活性)。此外,讨论了结构-活动关系的未来前景。本综述旨在为有针对性地调控膳食纤维的性质和活性提供理论依据。以提高其应用产品的质量和生理效率,实现膳食纤维资源的高值化利用。
    Dietary fibers come from a wide range of sources and have a variety of preparation methods (including extraction and modification). The different structural characteristics of dietary fibers caused by source, extraction and modification methods directly affect their physicochemical properties and functional activities. The relationship between structure and physicochemical properties and functional activities is an indispensable basic theory for realizing the directional transformation of dietary fibers\' structure and accurately regulating their specific properties and activities. In this paper, since a brief overview about the structural characteristics of dietary fiber, the effect of structural characteristics on a variety of physicochemical properties (hydration, electrical, thermal, rheological, emulsifying property, and oil holding capacity, cation exchange capacity) and functional activities (hypoglycemic, hypolipidemic, antioxidant, prebiotic and harmful substances-adsorption activity) of dietary fiber explored by researchers in last five years are emphatically reviewed. Moreover, the future perspectives of structure-activity relationship are discussed. This review aims to provide theoretical foundation for the targeted regulation of properties and activities of dietary fiber, so as to improve the quality of their applied products and physiological efficiency, and then to realize high value utilization of dietary fiber resources.
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  • 文章类型: Journal Article
    硬壳种业在全球农业经济中发挥着重要作用。事实上,只考虑榛子和核桃,全球坚果供应量超过5.6吨。因此,每年生产大量的产品,作为废物焚烧或丢弃,绕过有价值的化合物或特征的潜在来源。这篇评论涉及有关其化学组成以及功能应用的最新科学文献,以维持工业中主要副产品的利用。的确,由于它们的木质素,果壳受到了极大的兴趣,抗氧化剂,物理和机械特征。发现这些特性在种植品种和种植地点之间有所不同,影响物理和结构特征。关于果壳的上述性质的不一致导致探索榛子和核桃壳在可持续生物经济链中的应用状况。事实上,就潜在的应用而言,最先进的技术将它们的使用与建筑业和材料制造联系起来,如树脂或塑料复合材料,刨花板或建筑面板,或重要的基础设施,并作为水泥路面的填料。然而,它们目前的使用继续绕过它们巨大的抗氧化潜力和它们有趣的化学和机械特性。
    The hard-shelled seed industry plays an important role in the global agricultural economy. In fact, only considering hazelnut and walnut, the global nut supply is over 5.6 tons. As a result considerable amounts are produced year by year, burnt or discarded as waste, bypassing a potential source of valuable compounds or features. This review deals with the recent scientific literature on their chemical composition as well as functional applications as an approach to sustain the utilization of the main byproduct derived from industry. Indeed, nutshells have received great interest due to their lignin, antioxidant, physical and mechanical features. It was found that these properties vary among cultivars and localities of plantation, influencing physical and structural features. The inconsistencies regarding the above-mentioned properties of nutshells lead to exploring the status of hazelnut and walnut shell applications in sustainable bio-economy chains. In fact, in terms of potential applications, the state of the art links their use to the construction industry and the manufacture of materials, such as resin or plastic composites, particleboards or construction panels, or vital infrastructure and as a filler in cement pavements. However, their current use continues bypassing their great antioxidant potential and their interesting chemical and mechanical features.
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  • 文章类型: Journal Article
    食用花由于其独特的感官特性和健康益处而成为人类饮食的异国情调的部分。由于消费者要求食用花卉及其产品具有天然的新鲜度和较高的营养价值,关于绿色高效食用花卉加工技术的应用研究日益增多。本文回顾了包括超声在内的许多物理领域的应用,微波炉,红外线,紫外线,电离辐射,脉冲电场,高静水压力,并降低压力,旨在提高食用花卉的加工和产品质量。作用机制,影响因素,并对每个物理能量场的应用状况进行了严格评估。此外,评估了每个能量场的优缺点,并强调了他们未来前景的趋势。预计未来的研究将集中在对基于物理场的技术应用于食用花卉加工时的机理作用的更多了解,并为拓宽基于物理场的技术在工业领域的应用提供基础。
    Edible flowers are an exotic part of the human diet due to their distinct sensorial properties and health benefits. Due to consumers demand edible flowers and their products with natural freshness and high nutritional value, there is increasing research on the application of green and efficient edible flower processing technologies. This paper reviews the application of a number of physical fields including ultrasound, microwave, infrared, ultraviolet, ionizing radiation, pulse electric field, high hydrostatic pressure, and reduced pressure aiming to improve the processing and product quality of edible flowers. The mechanism of action, influencing factors, and status on application of each physical energy field are critically evaluated. In addition, the advantages and disadvantages of each of these energy fields are evaluated, and trends on their future prospects are highlighted. Future research is expected to focus on gaining greater understanding of the mechanism action of physical field-based technologies when applied to processing of edible flowers and to provide the basis for broaden the application of physical field-based technologies in industrial realm.
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  • 文章类型: Journal Article
    如今,疾病的治疗存在广泛的缺陷。这些限制与当前模式在预后中的低效能力有关,诊断,和治疗疾病。因此,有一个基本的需要开发新的方法来克服上述限制。壳聚糖(CS)纳米颗粒,具有显著的物理化学和机械性能,是FDA批准的具有潜在生物医学方面的生物材料,比如血清稳定性,生物相容性,生物降解性,粘膜粘附性,非免疫原性,抗炎,理想的药代动力学和药效学,等。基于CS的材料被提及为用于制造纳米纤维支架的理想生物活性材料。持续和受控的药物释放和原位凝胶化是这些支架的其他潜在优点。这篇综述强调了基于CS的创新纳米纤维支架作为再生医学和药物递送系统中潜在的生物活性材料的制造的最新进展,展望其未来应用。
    Nowadays, there is a wide range of deficiencies in treatment of diseases. These limitations are correlated with the inefficient ability of current modalities in the prognosis, diagnosis, and treatment of diseases. Therefore, there is a fundamental need for the development of novel approaches to overcome the mentioned restrictions. Chitosan (CS) nanoparticles, with remarkable physicochemical and mechanical properties, are FDA-approved biomaterials with potential biomedical aspects, like serum stability, biocompatibility, biodegradability, mucoadhesivity, non-immunogenicity, anti-inflammatory, desirable pharmacokinetics and pharmacodynamics, etc. CS-based materials are mentioned as ideal bioactive materials for fabricating nanofibrous scaffolds. Sustained and controlled drug release and in situ gelation are other potential advantages of these scaffolds. This review highlights the latest advances in the fabrication of innovative CS-based nanofibrous scaffolds as potential bioactive materials in regenerative medicine and drug delivery systems, with an outlook on their future applications.
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  • 文章类型: Journal Article
    膳食纤维在胃肠道中的理化性质,如水合性能,吸附性能,流变性能,对宿主消化吸收的生理过程有重要影响,导致饱腹感和葡萄糖和脂质代谢的差异。基于魔芋葡甘聚糖(KGM)的多种理化性质,回顾结构特征的关系是有意义的,理化性质和糖和脂质代谢。首先,本文绕过了肠道微生物的范畴,并从胶体营养的角度解释了膳食纤维在营养消化吸收过程中调节糖脂代谢的潜力。其次,讨论了KGM的修饰方法以调节其理化性质,并总结了KGM的分子结构类型与糖和脂质代谢的关系。最后,根据KGM的特点,综述了KGM在减脂食品主要原料和成分中的应用。希望这项工作能够为膳食纤维胶体营养科学的研究提供理论依据。
    The physicochemical properties of dietary fiber in the gastrointestinal tract, such as hydration properties, adsorption properties, rheological properties, have an important influence on the physiological process of host digestion and absorption, leading to the differences in satiety and glucose and lipid metabolisms. Based on the diversified physicochemical properties of konjac glucomannan (KGM), it is meaningful to review the relationship of structural characteristics, physicochemical properties and glycose and lipid metabolism. Firstly, this paper bypassed the category of intestinal microbes, and explained the potential of dietary fiber in regulating glucose and lipid metabolism during nutrient digestion and absorption from the perspective of colloidal nutrition. Secondly, the modification methods of KGM to regulate its physicochemical properties were discussed and the relationship between KGM\'s molecular structure types and glycose and lipid metabolism were summarized. Finally, based on the characteristics of KGM, the application of KGM in the main material and ingredients of fat reduction food was reviewed. We hope this work could provide theoretical basis for the study of dietary fiber colloid nutrition science.
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  • 文章类型: Journal Article
    多年来,壳聚糖由于其可再生性而被广泛认为是一种有前途的环保聚合物,生物相容性,生物降解性,无毒性,易于修改,给它未来发展的巨大潜力。作为阳离子多糖,壳聚糖表现出特定的物理化学,生物,和机械性能取决于其分子量和脱乙酰度等因素。最近,人们对壳聚糖衍生物和基于壳聚糖的纳米复合材料重新产生了兴趣。这种高度关注是由追求提高效率和扩大壳聚糖应用范围所驱动的。壳聚糖的适应性和独特的性质使其改变游戏规则,对从医疗保健到环境修复等行业做出了有希望的重大贡献。这篇综述介绍了壳聚糖生产来源和提取方法的最新概况,关注壳聚糖的理化性质,包括分子量,脱乙酰度和溶解度,以及它的抗菌,抗真菌和抗氧化活性。此外,我们强调了壳聚糖衍生物和生物聚合物改性方法的优点,随着壳聚糖基纳米复合材料制备的最新进展。最后,壳聚糖的广泛应用,无论是在它的原生状态,在各个领域衍生或结合到纳米复合材料中,比如食品工业,农业,化妆品行业,制药业,医学,和废水处理,进行了讨论。
    For many years, chitosan has been widely regarded as a promising eco-friendly polymer thanks to its renewability, biocompatibility, biodegradability, non-toxicity, and ease of modification, giving it enormous potential for future development. As a cationic polysaccharide, chitosan exhibits specific physicochemical, biological, and mechanical properties that depend on factors such as its molecular weight and degree of deacetylation. Recently, there has been renewed interest surrounding chitosan derivatives and chitosan-based nanocomposites. This heightened attention is driven by the pursuit of enhancing efficiency and expanding the spectrum of chitosan applications. Chitosan\'s adaptability and unique properties make it a game-changer, promising significant contributions to industries ranging from healthcare to environmental remediation. This review presents an up-to-date overview of chitosan production sources and extraction methods, focusing on chitosan\'s physicochemical properties, including molecular weight, degree of deacetylation and solubility, as well as its antibacterial, antifungal and antioxidant activities. In addition, we highlight the advantages of chitosan derivatives and biopolymer modification methods, with recent advances in the preparation of chitosan-based nanocomposites. Finally, the versatile applications of chitosan, whether in its native state, derived or incorporated into nanocomposites in various fields, such as the food industry, agriculture, the cosmetics industry, the pharmaceutical industry, medicine, and wastewater treatment, were discussed.
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  • 文章类型: Journal Article
    淀粉由于其性质的可用性而吸引食品工业,廉价,生物降解性和无限应用的可能性。淀粉性质及其改性影响食品质量。与其他谷物相比,块茎和根淀粉,需要更系统的关于Jicama淀粉(JS)的信息。这篇综述文章总结了隔离,composition,形态学,流变学,JS的热和消化性。还讨论了修改及其当前和潜在的应用。JS的化学成分和结构与其他淀粉不同,影响淀粉的性质。JS已通过物理和化学方法进行改性以改善淀粉的性能。然而,尽管JS已在食品配方中用作稳定剂并改善食品的质地,但与其他商业淀粉相比,对JS改性的研究很少。此外,它被用作可食用涂层,以保持食品的质量,并用作制造可食用和生物塑料包装的原料。然而,与商业淀粉相比,它对JS的大规模利用尚未探索。因此,这篇综述将为进一步研究木薯淀粉及其工业应用提供有用的信息和建议。
    Starch attracts food industries due to their availability in nature, cheapness, biodegradability and possibilities of endless applications. The starch properties and their modification affect food quality. Compared to other cereals, tuber and root starches, more systematic information is needed on the jicama starches (JS). This review article summarizes the isolation, composition, morphology, rheological, thermal and digestibility properties of JS. The modifications and its current and potential applications are also discussed. The chemical composition and structure of JS are different from other starches, influencing its properties. JS has been modified by physical and chemical methods to improve the properties of starch. However, there are very few studies on the modification of JS as compared with other commercial starch although it has been used in food formulation as a stabilizer and to improve the texture of food products. It is also applied as an edible coating to preserve the quality of food products and use as a raw material for making edible and bioplastic packaging. However, large-scale utilization of JS is unexplored compared to commercial starches. Therefore, this review would provide useful information and suggestions for more research on Jicama starch and its industrial applications.
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