背景:基底细胞腺瘤(BCA)是一种罕见的唾液腺良性肿瘤。基底细胞腺癌(BCAC),BCA的恶性对应物,也是一种非常罕见的肿瘤,临床研究非常有限。本研究旨在探讨其临床特点,人口统计,腮腺内诊断为BCA和BCAC的患者的手术结果。
方法:2003年5月至2023年8月对所有接受腮腺切除术的患者进行了回顾性分析。关于性别的回顾性数据,年龄,肿瘤特征,并收集结果。手术方法,包括实现负利润率,胶囊移除,和组织学诊断,也是详细的。
结果:该研究包括1268例接受腮腺切除术的患者,导致81例BCA和7例BCAC。BCA患者,平均年龄55.1岁,显示出不同的年龄分布,主要出现在50年代。在BCAC案例中,七名女性患者在深叶中表现出主要位置。FNA在7例病例中发现了BCAC,随后进行了腮腺切除术,导致未观察到复发或转移。
结论:这项研究报告了单个机构中数量最多的BCA病例,并提供了对人口统计学的全面见解,肿瘤特征,以及BCA和BCAC的临床结果。虽然需要进一步的研究,根据临床随访结果,在肿瘤切除术中适当地包括胶囊表明有利的结果,特别是当肿瘤大小不大时。
BACKGROUND: Basal cell adenoma (BCA) is a rare benign tumor within the salivary glands. Basal cell adenocarcinoma (BCAC), the malignant counterpart of BCA, is also an exceedingly rare tumor with very limited clinical studies conducted. This
study aims to investigate the clinical characteristics, demographics, and surgical outcomes of patients diagnosed with BCA and BCAC within the parotid gland.
METHODS: A retrospective analysis from May 2003 to August 2023 was performed for all patients undergoing parotidectomy for masses. Retrospective data on gender, age, tumor characteristics, and outcomes were collected. Surgical approaches, including negative margin attainment, capsule removal, and histological diagnosis, were also detailed.
RESULTS: The
study included 1268 patients who underwent parotidectomy, resulting in 81 cases of BCA and 7 cases of BCAC. BCA patients, with a mean age of 55.1 years, showed diverse age distribution and predominantly presented in the 50s. In BCAC cases, seven female patients exhibited a predominant location in the deep lobes. FNA revealed BCAC in three out of seven cases, and subsequent parotidectomy was performed, resulting in no observed recurrences or metastases.
CONCLUSIONS: This
study reports the largest number of BCA cases from a single institution and provides comprehensive insights into the demographics, tumor characteristics, and clinical outcomes of both BCA and BCAC. Although further research should be conducted, based on clinical follow-up results, appropriately including the capsule in the tumor excision indicates favorable outcomes, especially when the tumor size is not large.