Papuan

巴布亚
  • 文章类型: Journal Article
    自杀仍然是一个主要的公共卫生问题,每年有近100万人死亡。随着时间的推移,这一数字往往会增加,导致自杀自杀行为的因素也很复杂。然而,关于印度尼西亚艾滋病毒感染者(PLWH)的自杀行为和相关因素的证据很少。因此,本研究旨在评估接受Dolutegravir和Efavirenz治疗的土著和非土著HIV感染者自杀行为的患病率和相关因素.横截面数据是使用问卷收集的。参与者完成了自杀行为问卷修订(SBQ-R),抑郁焦虑应激量表-42(DASS-42),艾滋病毒污名-索威尔量表,和人口统计信息问题。结果是自我报告的自杀行为低和高,而logistic回归分析用于估计高自杀行为相关因素的校正比值比(aOR).共纳入200名PLWH,8.5%的参与者有高水平的自杀行为。大多数参与者是Efavirenz用户(84.0%),巴布亚人是土著人(75.5%)。一半以上受过高中教育(60.5%),女性(58%)已婚(54%)未付(59%)。多元logistic回归模型显示,土著(aOR=0.122;95%CI=0.029-0.514),和有孩子的人(aOR=0.221;95%CI=0.051-0.957)更有可能有低自杀行为。年龄在18-27岁之间的参与者(aOR=5.894;95%CI=1.336-30.579),具有较高的自责能力(AOR=1.342;95%CI)=1.004-1.792),可检测的HIV病毒载量(aOR=6.177;95CI=1.118-34.119)具有较高的自杀行为。这项研究确定了PLWH中自杀的风险很高,并且优先考虑常规自杀评估。这些发现对于干预设计和临床实践指南的开发也很有用,以管理PLWH的福祉,例如使用数字干预来应对障碍。
    Suicide remains a major public health problem, with nearly 1 million deaths per year. The number tends to increase over time and factors leading to suicide suicidal behaviors are complex. However, there is a paucity of evidence on suicidal behaviors and the associated factors among people living with HIV (PLWH) in Indonesia. Therefore, this study aimed to estimate the prevalence and associated factors of suicidal behavior between indigenous and non-indigenous living with HIV who were on Dolutegravir and Efavirenz therapies. The cross-sectional data were collected using questionnaires. Participants completed the Suicidal Behaviors Questionnaire-Revised (SBQ-R), Depression Anxiety Stress Scale-42 (DASS-42), HIV Stigma-Sowell Scale, and demographic information questions. The outcome was low and high self-reported suicidal behaviors, while logistic regression analyses were used to estimate adjusted odds ratios (aOR) for associated factors of high suicidal behaviors. A total of 200 PLWH were enrolled and 8.5% of the participants had high levels of suicidal behaviors. The majority of participants were Efavirenz users (84.0%), and Papuans as Indigenous (75.5%). More than half had a high school education (60.5%), were female (58%), married (54%), and unpaid (59%). The multiple logistic regression model showed that indigenous (aOR = 0.122; 95% CI = 0.029-0.514), and people who had children (aOR = 0.221; 95% CI = 0.051-0.957) were more likely to have low suicidal behaviors. Participants who were aged 18-27 years (aOR = 5.894; 95% CI = 1.336-30.579), had high self-blame (aOR = 1.342; 95% CI) = 1.004-1.792), and detectable HIV viral load (aOR = 6.177; 95%CI = 1.118-34.119) had high suicidal behavior. This study identified the risk of suicidality among PLWHs is high and routine suicide assessment is prioritized. The findings are also useful for intervention design and the development of clinical practice guidelines to manage the well-being of PLWH such as using digital intervention to cope with hindrances.
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  • 文章类型: Journal Article
    The \'root infinitive\' phenomenon in child speech is known from major languages such as Dutch. In this case study, a child acquiring the Papuan language Nungon in a remote village setting in Papua New Guinea uses two different non-finite verb forms as predicates of main clauses (\'root\' contexts) between ages 2;3 and 3;3. The first root non-finite form is an apparent innovation of the child, unacceptable in adult-to-adult speech, which must be learned from a special auxiliary construction in child-directed speech. The second root non-finite form functions like attested adult main clause use of the same form. During the study period, the first root non-finite form increases sharply to function as a default verb form, then decreases to nil by 3;2. The second increases gradually to near-adult levels. Both forms are non-finite and have similar proportions in the input. Thus, factors other than finiteness and frequency must explain their distributions.
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  • 文章类型: Journal Article
    Sequencing of complete nuclear genomes of Neanderthal and Denisovan stimulated studies about their relationship with modern humans demonstrating, in particular, that DNA alleles from both Neanderthal and Denisovan genomes are present in genomes of modern humans. The Papuan genome is a unique object because it contains both Neanderthal and Denisovan alleles. Here, we have shown that the Papuan genomes contain different gene functional groups inherited from each of the ancient people. The Papuan genomes demonstrate a relative prevalence of Neanderthal alleles in genes responsible for the regulation of transcription and neurogenesis. The enrichment of specific functional groups with Denisovan alleles is less pronounced; these groups are responsible for bone and tissue remodeling. This analysis shows that introgression of alleles from Neanderthals and Denisovans to Papuans occurred independently and retention of these alleles may carry specific adaptive advantages.
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