PREVENTIVE MEDICINE

预防性药物
  • 文章类型: Journal Article
    背景:宫颈癌发病率和死亡率在佛得角排名第三。了解与宫颈癌筛查(CCS)年龄相关的因素至关重要,因为它有助于识别有延迟筛查风险的人群。能够进行有针对性的干预,以确保及时发现和治疗,最终减轻宫颈癌的负担。我们研究了佛得角成年女性首次筛查宫颈癌时与年龄相关的因素。
    方法:使用来自2020年WHOSTEP调查的数据。我们分析了1,082名30-69岁女性的数据,这些女性曾经筛查过宫颈癌。在STATA第18版中计算了双变量和多变量逻辑回归模型。
    结果:总体而言,研究中,有30.6%的女性在30岁之前或30岁时患有首次CCS。除了在过去12个月内访问医疗机构外,在粗模型中,所有变量均显着预测女性的CCS第一年龄。在调整后的模型中,与没有接受过正规教育的女性相比,接受过高等教育的女性显示出更大的几率[AORs=9.85;95%CI:4.12-23.54].与那些从未结过婚的人相比,既往已婚女性早期筛查的几率显著较低[AOR=0.63;95%CI:0.39~0.99].与高血压患者相比,没有高血压的女性早期筛查的几率更高[AOR=1.66;95%CI:1.18-2.34]。此外,目前工作的女性早期筛查的几率显著高于失业的女性[AOR=1.49;95%CI:1.09-2.04].
    结论:结论:实施有针对性的教育运动,解决社会经济障碍,将宫颈癌筛查纳入常规医疗保健服务可以提高佛得角妇女的早期筛查率。有必要将CCS纳入高血压妇女的常规医疗保健服务中。此外,正规教育和初筛年龄之间的正相关,佛得角公共卫生部门必须在学校内实施全面的教育计划,以提高对CCS的认识。
    BACKGROUND: Cervical cancer ranks third in terms of cancer incidence and mortality in Cape Verde. Understanding the factors associated with the age of cervical cancer screening (CCS) is essential because it helps identify populations at risk of delayed screening, enabling targeted interventions to ensure timely detection and treatment, ultimately reducing the burden of cervical cancer. We examined the factors associated with age at first screening for cervical cancer among adult Cape Verdean women.
    METHODS: Data from the 2020 WHO STEPs survey were used. We analyzed data from 1,082 women aged 30-69 years who had ever screened for cervical cancer. Bivariable and multivariable logistic regression models were computed in STATA version 18.
    RESULTS: Overall, 30.6% of women in the study had their first CCS before or at age 30. Except for visits to the health facility within the last 12 months, all variables significantly predicted women\'s first age for CCS in the crude model. In the adjusted model, women with tertiary education showed greater odds [AORs = 9.85; 95% CI: 4.12-23.54] compared to those with no formal education. Compared to those who were never married, previously married women had significantly lower odds of screening at an early age [AOR = 0.63; 95% CI: 0.39-0.99]. Women without hypertension had higher odds [AOR = 1.66; 95% CI: 1.18-2.34] of early screening compared to those with hypertension. Also, women who were currently working had significantly higher odds of early screening than those unemployed [AOR = 1.49; 95% CI: 1.09-2.04].
    CONCLUSIONS: In conclusion, implementing targeted educational campaigns, addressing socio-economic barriers, and integrating cervical cancer screening into routine healthcare services can increase the early screening uptake among Cape Verdean women. There is a need to integrate CCS in the routine healthcare services of women living with hypertension. Also, the positive association between formal education and age at first screening, it is imperative for the Cape Verdean public health departments to implement comprehensive education programs within schools to promote awareness about CCS.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    背景:评估多学科的康复策略对于先发制人地对抗身体,急性髓系白血病(AML)和骨髓增生异常综合征(MDS)患者的异基因造血干细胞移植(allo-HSCT)过程中经历的心理和社会负面影响。目前的证据仅限于诱导化疗期间的研究,省略康复干预措施,主要使用仅运动的方法,而没有多学科框架。这项研究的目的是探讨可行性,成人多学科康复的安全性和初步疗效提供allo-HSCT。
    方法:这项为期8周的单组可行性研究旨在为接受allo-HSCT的参与者试行多学科康复干预,注重可行性和安全性。参与者,18岁或以上,诊断为AML或MDS,并提供allo-HSCT,将在2023年6月至2024年7月期间招募。多学科康复干预,由皇家阿德莱德医院的癌症专职医疗小组进行,包括运动生理学,物理治疗,营养学,社会工作,职业治疗和心理干预。与多学科治疗方法一致,每个组件都是针对患者护理的不同方面量身定制的,和依从性计算将评估患者的参与度和依从性。此外,参与者将继续接受癌症专职医疗人员的常规护理。该研究的主要结果是通过评估干预措施的吸收来评估多学科康复干预的可行性。保留,坚持,可接受性和安全性。次要结果是腿部力量,上身强度,有氧健身,跌倒风险,人体测量学,营养状况,生活质量,焦虑,抑郁症,应对癌症和痛苦的自我效能感。
    背景:本研究的伦理批准已由阿德莱德中央地方卫生网络(HREC2022/HRE00284)提供。该研究的招聘始于2023年6月,并将持续到2024年7月。这些方法已根据SPIRIT和CONSORT试点研究清单进行了设计和报告。
    背景:澳大利亚新西兰临床试验注册中心(ANZCTR):ACTRN12623000052639。
    BACKGROUND: Assessing multidisciplinary prehabilitation strategies becomes crucial to pre-emptively counter the physical, psychological and social negative impacts experienced during an allogenic haematopoietic stem cell transplant (allo-HSCT) among acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS) patients. Current evidence is restricted to studies during induction chemotherapy, omitting rehabilitation interventions and predominantly using exercise-only approaches without a multidisciplinary framework. The aim of this study is to investigate the feasibility, safety and preliminary efficacy of multidisciplinary prehabilitation in adults offered allo-HSCT.
    METHODS: This 8-week single-group pre-post feasibility study aims to pilot a multidisciplinary prehabilitation intervention for participants undergoing allo-HSCT, with a focus on feasibility and safety. Participants, aged 18 or older, diagnosed with AML or MDS, and offered allo-HSCT, will be recruited between June 2023 and July 2024. The multidisciplinary prehabilitation intervention, conducted by the cancer allied health team at the Royal Adelaide Hospital, includes exercise physiology, physiotherapy, dietetics, social work, occupational therapy and psychology interventions. Consistent with a multidisciplinary treatment approach, each component is tailored to address different aspects of patient care, and adherence calculations will assess patient engagement and compliance. In addition, participants will continue to receive usual care from cancer allied health staff. The primary outcome of the study is to assess the feasibility of a multidisciplinary prehabilitation intervention by evaluating intervention uptake, retention, adherence, acceptability and safety. Secondary outcomes are leg strength, upper-body strength, aerobic fitness, falls risk, anthropometry, nutritional status, quality of life, anxiety, depression, self-efficacy for coping with cancer and distress.
    BACKGROUND: Ethics approval for this study has been provided by the Central Adelaide Local Health Network (HREC 2022/HRE00284). Recruitment for the study commenced in June 2023 and will continue until July 2024. The methods have been designed and are reported according to the SPIRIT and CONSORT-pilot study checklist.
    BACKGROUND: The Australian New Zealand Clinical Trials Registry (ANZCTR): ACTRN12623000052639.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:职业病是与就业有关的最重要的健康问题之一。在马来西亚,很少有流行病学研究讨论这些问题,尤其是行业内的工人。为此,这项研究旨在筛选来自高风险工业部门的工人,识别工作场所的危害,并建议工作场所的改进措施,以防止职业病。
    方法:这是一个为期3年的项目,将使用基于网络的筛查工具对来自马来西亚所有13个州的100000名工人进行调查,该工具包括两部分:职业病筛查工具和危害识别,风险评估和风险控制方法。数据将使用多阶段分层抽样方法从500家公司收集,包括七个关键工业部门。独立变量将是社会人口统计学特征,合并症,既往病史,高风险行为和工作场所概况。因变量将是职业病的类型(噪声引起的听力损失,呼吸,肌肉骨骼,神经毒性,皮肤和精神障碍)。随后,将获得将中高风险工人转介到职业健康诊所的建议。经批准的职业健康服务诊所/提供者将在认为必要时对每个病例进行确认性诊断。随后,将进行穿行调查,以确定工作场所的危害,并建议工作场所的改善措施,以预防这些职业病。这项研究将使用描述性和推断性统计数据。将使用简单和调整后的二元回归来查找职业病的决定因素。
    背景:这项研究已获得MARA大学技术研究伦理委员会的批准。Informed,将获得所有研究参与者的书面同意.调查结果将分发给职业健康和安全部,涉及的行业,并通过同行评审的出版物。
    BACKGROUND: Occupational diseases are one of the most important health problems related to employment However, in Malaysia, there are few epidemiological studies discussing these issues, especially among workers in the industry. For that, this study aimed to screen workers from high-risk industrial sectors, identify hazards in the workplace and recommend improvement measures in the workplace to prevent occupational diseases.
    METHODS: This is a 3-year project in which a survey of 100 000 workers from all 13 states in Malaysia will be conducted using a web-based screening tool that is comprised of two parts: occupational disease screening tool and hazard identification, risk assessment and risk control method. Data will be collected using a multistage stratified sampling method from 500 companies, including seven critical industrial sectors. The independent variables will be sociodemographic characteristics, comorbidities, previous medical history, high-risk behaviour and workplace profile. The dependent variable will be the types of occupational diseases (noise-induced hearing loss, respiratory, musculoskeletal, neurotoxic, skin and mental disorders). Subsequently, suggestions of referral for medium and high-risk workers to occupational health clinics will be attained. The approved occupational health service clinics/providers will make a confirmatory diagnosis of each case as deemed necessary. Subsequently, a walk-through survey to identify workplace hazards and recommend workplace improvement measures to prevent these occupational diseases will be achieved. Both descriptive and inferential statistics will be used in this study. Simple and adjusted binary regression will be used to find the determinants of occupational diseases.
    BACKGROUND: This study has been approved by the MARA University of Technology Research Ethics Board. Informed, written consent will be obtained from all study participants. Findings will be disseminated to the Department of Occupational Health and Safety, involved industries, and through peer-reviewed publications.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:运动员的流感疫苗接种是运动医学的一个重要领域。这个描述性的,横断面研究旨在探讨年轻运动员流感疫苗的疫苗接种实践和意图。
    方法:结构化,在希腊国家体育学院的学生中进行了基于问卷的研究。该调查是在2023年4月至5月期间进行的。总的来说,138名参与者参与了这项研究。
    结果:超过一半的参与者过去曾接种过流感疫苗,但是在2022-2023年,只有12.3%的人接种了流感疫苗。主要原因似乎是缺乏时间(40.6%)和流感不会对参与者造成任何严重的健康威胁(36.2%)。影响他们是否接种流感疫苗的主要因素是需要更多关于流感疫苗接种的信息(79%)。
    结论:最近的研究表明,参加体育活动的年轻人的疫苗接种覆盖率较低。参与者的定性观点强调了缺乏由卫生专业人员和教练提供的组织良好的信息计划的重要性。
    BACKGROUND: Influenza vaccination among athletes is a crucial area in sports medicine. This descriptive, cross-sectional study aims to explore the vaccination practices and intentions regarding influenza vaccines among young athletes.
    METHODS: A structured, questionnaire-based study was conducted among students from the National School of Sports in Greece. The survey was conducted over the period of April to May 2023. Overall, 138 participants participated in the study.
    RESULTS: More than half of the participants had received a flu vaccine in the past, but only 12.3% were vaccinated against influenza for 2022-2023. The main reasons seemed to be the lack of time (40.6%) and the idea that influenza does not lead to any serious health threats for the participants (36.2%). The main factor that affected their decision to get the flu vaccine or not was the need for more information regarding influenza vaccination (79%).
    CONCLUSIONS: The recent study showed low vaccination coverage among people of young age participating in sports activities. The qualitative views of the participants highlighted the significance of the lackof a well-organized information program provided by health professionals and coaches.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目的:培训不足和指南缺失会增加酷刑幸存者在外科手术期间再次遭受创伤的风险。本研究旨在制定指南以减轻这种风险,并收集医疗保健专业人员治疗酷刑幸存者的经验以及对指南的可行性和可接受性的见解。
    方法:本研究分两个阶段进行。“a”阶段涉及根据对酷刑幸存者的审查制定指导方针,“在躯体护理和潜在的再创伤触发因素中遇到的情况”,以及一项关于幸存者在手术干预期间经历的定性研究。开发过程坚持建议评估的分级,开发和评估(等级)原则和评估方法学严谨的研究和评估指南(AGREEII)工具。“b”阶段涉及焦点小组和对医疗保健专业人员的个人访谈,以探索照顾酷刑幸存者的挑战并评估指南。
    方法:研究,于2023年5月至8月进行,来自挪威南部和东南部三家医院的外科部门的参与者参与其中。
    方法:21名医疗保健专业人员,包括外科医生,麻醉师,护士和牙医,参与研究。进行了焦点小组访谈和个人访谈。
    结果:阶段\'a\':制定了包括六个部分的指南:介绍,一般指南和涵盖术前的四个部分,围手术期和术后手术阶段。b阶段:医疗保健专业人员努力了解酷刑的复杂性并确定幸存者的独特需求。他们面临挑战使用口译员和协助患者的强烈反应。虽然这些准则被认为对提高认识是实用和有用的,他们的长度受到质疑。
    结论:我们为在接受手术治疗的酷刑幸存者中预防再创伤提供了建议。该指南可以作为为酷刑幸存者提供安全和个性化护理的起点。教学机构和医院可以将指南纳入医疗保健专业人员的教育。
    OBJECTIVE: Insufficient training and the absence of guidelines increase the risk of retraumatisation in torture survivors during surgical procedures. This study aims to develop guidelines to mitigate this risk and gather healthcare professionals\' experiences treating torture survivors and insights on the guideline\'s feasibility and acceptability.
    METHODS: The study was conducted in two phases. Phase \'a\' involved developing guidelines based on reviews of torture survivors\' encounters in somatic care and potential retraumatisation triggers, as well as a qualitative study on survivors\' experiences during surgical interventions. The development process adhered to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) principles and the Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument for methodological rigour. Phase \'b\' involved focus groups and individual interviews with healthcare professionals to explore challenges in caring for torture survivors and to evaluate the guidelines.
    METHODS: The study, conducted from May to August 2023, involved participants from surgical departments in three hospitals in southern and southeastern Norway.
    METHODS: Twenty-one healthcare professionals, including surgeons, anaesthesiologists, nurses and a dentist, participated in the study. Both focus group interviews and individual interviews were conducted.
    RESULTS: Phase \'a\': guidelines comprising six sections were developed: an introduction, general guidelines and four sections covering the preoperative, perioperative and postoperative surgical stages. Phase \'b\': healthcare professionals struggled to understand torture\'s complexities and identify survivors\' unique needs. They faced challenges using interpreters and assisting patients with strong reactions. While the guidelines were viewed as practical and useful for raising awareness, their length was questioned.
    CONCLUSIONS: We provide recommendations for preventing retraumatisation in torture survivors undergoing surgical treatment. The guidelines may serve as a starting point for offering safe and individualised care to torture survivors. Teaching institutions and hospitals may incorporate the guidelines into healthcare professionals\' education.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:青少年使用电子烟,在全球和澳大利亚境内,近年来有所增加。作为回应,公共卫生机构呼吁制定针对青少年的教育和交流计划。尽管有这样的建议,目前对此类干预措施的严格评估很少。这项研究的主要目的是检查针对父母和青少年的短信干预对青少年使用电子烟易感性的潜在影响(例如,使用电子烟的意图)。次要目标是(1):检查干预措施对青少年电子烟和可燃烟草使用的影响,以及(2)检查干预措施的可接受性。
    方法:一项采用2×2因子设计的随机对照试验将对父母-青少年(12-15岁)进行。Dyads将被随机分配到四个手臂之一:手臂1-仅向青少年提供短信干预;手臂2-仅向青少年父母提供短信干预;手臂3-向父母和青少年提供短信干预;手臂4-仅控制信息,由只提供给父母的电子烟概况表组成。参与者招募于2023年3月开始,目的是招募120名父母-青少年二元组合。评估研究结果的数据收集将在基线进行,干预开始后的6、12和24个月。主要终点是6个月的随访。主要结果将是青少年容易使用电子烟,使用经过验证的项目进行评估。将在意向治疗框架下对试验结果进行分析,将所有参与者纳入被分配组的分析范围.
    背景:伦理学已获得纽卡斯尔大学人类研究伦理学委员会的批准(H-2022-0340)。研究结果将在同行评审的期刊和会议上传播。
    背景:该试验在澳大利亚新西兰临床试验注册中心(ACTRN12623000079640)进行了前瞻性注册。
    BACKGROUND: Adolescent e-cigarette use, globally and within Australia, has increased in recent years. In response, public health agencies have called for the development of education and communication programmes targeting adolescents. Despite such recommendations, few rigorous evaluations of such interventions currently exist. The main objective of this study is to examine the potential effect of a text message intervention targeting parents and adolescents on adolescent susceptibility to e-cigarette use (eg, intentions towards using e-cigarettes). Secondary objectives are to (1): examine the effect of the intervention on adolescent e-cigarette and combustible tobacco use and (2) examine the acceptability of the intervention.
    METHODS: A randomised controlled trial employing a 2×2 factorial design will be conducted with parent-adolescent dyads (aged 12-15 years). Dyads will be randomly allocated to one of four arms: arm 1-a text message intervention delivered to adolescents only; arm 2-a text message intervention delivered to the parents of adolescents only; arm 3-a text message intervention delivered to both the parents and adolescents; and arm 4-an information only control, consisting of an e-cigarette factsheet provided to parents only. Participant recruitment commenced in March 2023 with the aim to recruit 120 parent-adolescent dyads. Data collection to assess study outcomes will occur at baseline, 6, 12 and 24 months post the commencement of the intervention. The primary endpoint will be 6-month follow-up. The primary outcome will be adolescent susceptibility to e-cigarette use, assessed using validated items. Analyses of trial outcomes will be undertaken under an intention-to-treat framework, with all participants included in the analysis in the group they were allocated.
    BACKGROUND: Ethics approval has been obtained from the human research ethics committee of the University of Newcastle (H-2022-0340). Findings will be disseminated in peer-reviewed journals and at conferences.
    BACKGROUND: The trial was registered prospectively with Australian New Zealand Clinical Trials Registry (ACTRN12623000079640).
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:由于与年龄相关的下降和撞车死亡率的增加,老年驾驶员的不断增长对道路安全提出了挑战。然而,使老年人能够通过持续的安全驾驶来保持健康和独立是很重要的。这项研究的重点是迫切需要具有成本效益的干预措施,以降低撞车风险,同时支持老年驾驶员更长时间的安全驾驶。我们的研究旨在评估三种行为干预措施对老年驾驶员安全的有效性。其中包括在线道路规则复习研讨会,量身定制的驾驶性能反馈和两个量身定制的驾驶课程。
    方法:一项单盲三平行组优势随机对照试验将对198名65岁及以上的城市持牌司机进行,允许4%的减员。该样本大小提供80%的功率来检测具有0.05的α的差异。参与者将根据标准化的道路测试进行选择,该测试将他们识别为中度不安全的驾驶员。干预措施,跨越3个月的时间,旨在提高驾驶安全性。其有效性将通过在干预后3个月(T1)和12个月(T2)对驾驶安全进行标准化的道路评估来评估。此外,每月自我报告的驾驶日记将提供有关撞车和事故的数据。该试验有可能确定具有成本效益的方法来提高老年驾驶员的安全性,并有助于基于证据的健康政策。临床实践和指南。
    背景:新南威尔士大学人类研究伦理委员会(HC190439,2019年8月22日)获得了伦理批准。研究结果将在同行评审的期刊和研究会议上传播。
    背景:ACTRN12622001515785。
    BACKGROUND: The growing population of older drivers presents challenges for road safety attributed to age-related declines and increased crash fatality rates. However, enabling older people to maintain their health and independence through continued safe driving is important. This study focuses on the urgent need for cost-effective interventions that reduce crash risk while supporting older drivers to remain driving safely for longer. Our study aims to evaluate the effectiveness of three behavioural interventions for older driver safety. These include an online road-rules refresher workshop, tailored feedback on driving performance and two tailored driving lessons.
    METHODS: A single-blind three-parallel group superiority randomised controlled trial will be conducted with 198 urban licensed drivers aged 65 years and older, allowing for 4% attrition. This sample size provides 80% power to detect a difference with an alpha of 0.05. Participants will be selected based on a standardised on-road test that identifies them as moderately unsafe drivers. Interventions, spanning a 3-month period, aim to improve driving safety. Their effectiveness will be assessed through a standardised on-road assessment of driving safety at 3 months (T1) and 12 months postintervention (T2). Additionally, monthly self-reported driving diaries will provide data on crashes and incidents.This trial has the potential to identify cost-effective approaches for improving safety for older drivers and contribute to evidence-based health policy, clinical practice and guidelines.
    BACKGROUND: Ethical approval was obtained by the University of New South Wales Human Research Ethics Committee (HC190439, 22 August 2019). The results of the study will be disseminated in peer-reviewed journals and research conferences.
    BACKGROUND: ACTRN12622001515785.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目的:关于青少年农村人群听力损失的研究趋势有限,目前的证据表明,扩展高频测听可以作为检测亚临床听力损失的敏感工具。此外,当前的研究强调了在科学中代表不同种族人口的重要性。这项研究旨在确定哥伦比亚农村地区非洲裔哥伦比亚青少年通过常规纯音(0.25-8kHz)和扩展高频(EHF)(9-20kHz)测听法获得的听力损失的患病率。
    方法:观察性,横断面研究。
    方法:230名13-17岁的非洲裔哥伦比亚青少年在卡塔赫纳农村人口中就读高中,哥伦比亚。
    方法:耳镜检查,在2021年2月至3月期间进行了常规(0.25-8kHz)和EHF(9-20kHz)测听测试.社会人口统计学和相关因素问卷也用于评估与EHF听力损失相关的可能因素。
    方法:使用常规和EHF测听法对获得性听力损失的患病率,以及与听力损失相关的因素。
    结果:在符合资格标准的230名青少年中,133人(57.82%)为女性。平均年龄为15.22岁(SD:1.62)。用常规测听法评估的至少一只耳朵的听力损失患病率为21.30%,用EHF测听法评估的听力损失患病率为14.78%。耳镜检查的主要异常结果包括:新鼓膜(1.30%),肌硬化(0.87%)和单体疤痕(0.43%)。通过逻辑回归发现的与EHF听力损失的较高概率相关的因素是年龄较大(患病率比(PR):1.45;95%CI1.16至1.80),每月参加“Picó”四次或更多次(PR:6.63;95%CI2.16至20.30),每月参加酒吧三次以上(PR:1.14;95%CI1.03至1.59)和自我报告听力困难(PR:1.24;95%CI1.22至4.05)。
    结论:我们的研究结果表明,获得性听力损失在农村年轻人群中已经普遍存在。
    OBJECTIVE: Research trends concerning hearing loss within teen rural populations are limited and current evidence suggests that extended high-frequency audiometry can be a sensitive tool to detect subclinical hearing loss. Moreover, current research emphasises the importance of representing different ethnic populations in science. This study aimed to determine the prevalence of acquired hearing loss through conventional pure-tone (0.25-8 kHz) and extended high frequency (EHF) (9-20 kHz) audiometry in Afro-Colombian adolescents from a rural area in Colombia.
    METHODS: Observational, cross-sectional study.
    METHODS: 230 Afro-Colombian adolescents aged 13-17 years who attended high school in a rural population from Cartagena, Colombia.
    METHODS: Otoscopic examination, conventional (0.25-8 kHz) and EHF (9-20 kHz) audiometry tests were performed during February-March 2021. Sociodemographic and associated factor questionnaires were also applied to assess probable factors associated with EHF hearing loss.
    METHODS: Prevalence of acquired hearing loss using conventional and EHF audiometry, and factors associated with hearing loss.
    RESULTS: Of 230 adolescents who met the eligibility criteria, 133 (57.82%) were female. The mean age was 15.22 years (SD: 1.62). The prevalence of hearing loss in at least one ear assessed with conventional audiometry was 21.30% and with EHF audiometry 14.78%. The main abnormal otoscopic findings included: neotympanum (1.30%), myringosclerosis (0.87%) and monomeric scars (0.43%). Factors associated with a higher probability of EHF hearing loss found through logistic regression were older age (prevalence ratio (PR): 1.45; 95% CI 1.16 to 1.80), attending the \'Picó\' four or more times a month (PR: 6.63; 95% CI 2.16 to 20.30), attending bars more than three times a month (PR: 1.14; 95% CI 1.03 to 1.59) and self-reported hearing difficulties (PR: 1.24; 95% CI 1.22 to 4.05).
    CONCLUSIONS: Our results suggest that acquired hearing loss is already widespread among this young rural population.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目标:堪萨斯城的一个基层环境正义组织一直在研究居住在美国最大的分类铁路场的居民对空气污染的不成比例的暴露。先前的分析表明,居住在靠近毒性释放库存(TRI)设施和铁路场的哮喘患者的哮喘恶化风险有限。在这项研究中,我们评估了地理哮喘和环境差异,进一步探索社区层面的差距。
    方法:这是一项针对人群水平哮喘发病率的横断面研究,其中包括所有哮喘发作率和急性哮喘发作率(紧急护理,急诊科,住院)。从人口普查区质心到最近的TRI设施的距离,计算了铁路和高速公路。使用Kendallτ相关和多变量Poisson回归模型检查哮喘发病率和距离之间的关联。
    方法:我们使用地区儿科医院的电子病历数据,人口普查和环境保护局(EPA)空气监测数据。
    方法:在EPA研究时间范围内发现2+哮喘患者。
    结果:住宅与铁路站的距离与总体(-0.36(CI-0.41至-0.32))和急性(-0.27(CI-0.32至-0.22))哮喘发生率呈显著负相关。与南部方向性相比,最近的铁路场以北的地区的哮喘发生率升高(发生率比:1.38;CI1.35至1.41)。距最近的铁路站3公里的距离增加与总哮喘发生率降低26%有关。
    结论:观察到接近所有污染源类型与哮喘发病率之间存在显著负相关。这项社区一级的研究已成为社区参与的工具,并将用于支持拟议的地方政策。环境司法工作解决了涉及小,有限的数据集,如果数据存在。学术流行病学平台可能会重新考虑可接受的小人口研究方法,以便更好地为最需要的社区提供服务。
    OBJECTIVE: A grassroots environmental-justice organisation in Kansas City has been examining the disproportionate exposure to air pollution experienced by residents living fenceline to the largest classification railyard in the USA. Prior analyses showed limited increased risk for asthma exacerbation for patients with asthma living closer to toxic release inventory (TRI) facilities and railyards. In this study, we assessed geographical asthma and environmental disparities, to further explore community-level disparities.
    METHODS: This is a cross-sectional study of population-level asthma rates, which included rates for all asthma encounters and acute asthma encounters (urgent care, emergency department, inpatient admission). Distances from census-tract centroids to nearest TRI facilities, railyards and highways were calculated. The association between asthma rates and distances was examined using Kendall\'s τ correlation and multivariable Poisson regression models.
    METHODS: We used electronic medical record data from the regional paediatric hospital, census and Environmental Protection Agency (EPA) air monitoring data.
    METHODS: Patients with 2+ asthma encounters during the EPA study timeframe were identified.
    RESULTS: Residential distance from railyards exhibited a significant negative correlation with overall (-0.36 (CI -0.41 to -0.32)) and acute (-0.27 (CI -0.32 to -0.22)) asthma rates. Asthma rates were elevated among tracts north of the closest railyard (incident rate ratio: 1.38; CI 1.35 to 1.41) when compared with southern directionality. An increased distance from the nearest railyard of 3 km was associated with a decrease in overall asthma rates of 26%.
    CONCLUSIONS: Significant negative associations between proximity to all pollution source types and asthma rates were observed. This community-level research has served as a tool for community engagement and will be used to support proposed local policy. Environmental justice work addresses local concerns involving small, limited datasets, if the data exist at all. The academic epidemiological platform may reconsider acceptable approaches to small population research in order to better serve communities with the most need.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Clinical Trial Protocol
    背景:由于文化认同与历史的纠缠,在更孤立的地区理解自杀是一个挑战,地理和社会文化的特殊性。这些知识是在法国海外领土(FOT)等地区实施有针对性的预防策略的必要前提,关于自杀危险因素的数据仍然不完整。我们旨在通过将新颖的人类学和心理语言学方法整合到心理尸检方法中来解决社会文化和临床自杀风险因素。本文介绍了临床研究的协议“心理尸检对理解法国海外自杀行为的贡献”(AUTOPSOM研究),旨在识别四个FOT中常见或新的特定自杀风险因素。
    方法:将在四个FOT中进行多中心流行病学研究(法属波利尼西亚,马提尼克岛,留尼汪岛和法属圭亚那)以及法国大陆(LaSomme)的比较站点。该方法将基于混合方法(定量和定性)方法,使用心理尸检来收集死者生命中的临床数据和生活事件。我们实施了一种探索性的多方法策略,结合了一系列流行病学,人类学,心理语言学和心理学方法,对自杀亲属的话语进行半自动分析。
    背景:研究方案(第一版)由法国伦理委员会批准(CPPOUESTII,批准#22.04267.000122)和法属波利尼西亚伦理委员会(2022年4月5日JOPF;2022年3月29日CEPF意见n°91)。研究结束时建立的总体结果和观点将根据他们的意愿传达给失去亲人的亲属,并用于当地的自杀预防目的。
    背景:NCT05773898。
    BACKGROUND: Understanding suicide in more isolated territories is a challenge because of the entanglement of cultural identity with historical, geographical and sociocultural specificities. This knowledge is a necessary precondition for the implementation of targeted prevention strategies in regions such as the French overseas territories (FOT), where data concerning suicidal risk factors is still incomplete. We aim to untangle sociocultural and clinical suicide risk factors by integrating a novel anthropological and psycholinguistic approach into the psychological autopsy method. This article describes the protocol of the clinical study \'Contribution of Psychological Autopsy to the Understanding of Suicidal Behaviours in Overseas France\' (AUTOPSOM study), designed to identify common or new specific suicide risk factors in four FOT.
    METHODS: A multicentre epidemiological study will be carried out in four FOTs (French Polynesia, Martinique, La Reunion and French Guiana) and at a comparison site in mainland France (La Somme). The methodology will be based on a mixed-methods (quantitative and qualitative) approach using a psychological autopsy to collect clinical data and life events in the deceased\'s life. We implemented an exploratory multimethod strategy that combines a succession of epidemiological, anthropological, psycholinguistic and psychological methods with a semiautomated analysis of the discourse of relatives bereaved by suicide.
    BACKGROUND: The study protocol (first version) was approved by the French Ethics Committee (CPP OUEST II, approval #22.04267.000122) and the Ethics Committee of French Polynesia (JOPF of 5 April 2022; CEPF opinion n°91 of 29 March 2022). The overall results and the perspectives established at the end of the study will be communicated to the bereaved relatives according to their will and serve for local suicide prevention purposes.
    BACKGROUND: NCT05773898.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

公众号