■地中海贫血是一种常见疾病，其治疗通常基于脾切除术。与全脾切除术相关的风险刺激部分脾切除术作为潜在的替代疗法。
■一名45岁女性患者因β地中海贫血中期长期随访开始出现脾功能亢进和铁超负荷征象。进行了部分脾切除术，观察到血液学明显改善，同时保留了所需的脾功能。
■部分脾切除术证明在保持脾吞噬功能完整性的同时，溶血率持续下降，表现为全脾切除术的有效替代方案。在接受部分脾切除术后，我们的患者经历了持续的溶血控制,并且没有出现脾功能亢进或铁超负荷的迹象.未观察到脾再生或感染并发症。部分脾切除术的主要缺点是术中和术后出血的风险增加，脾残余扭转和脾再生。
■部分脾切除术是治疗成人中间型β地中海贫血患者的一种替代方法，避免了与全脾切除术相关的风险。
UNASSIGNED: Thalassemia is a common disease which treatment is often based on splenectomy. The risks associated with total splenectomy stimulated partial splenectomy as a potentially alternative therapy.
UNASSIGNED: A 45 year-old female patient with long term follow-up for β thalassemia intermedia started to develop signs of hypersplenism and iron overload. A partial splenectomy was performed and was observed a marked hematologic improvement while preserving the desired splenic function.
UNASSIGNED: Partial splenectomy proved to provide a persistent decrease in hemolytic rate while preserving the integrity of splenic phagocytic function, presenting itself as an effective alternative to total splenectomy. After being subjected to partial splenectomy, our patient experienced a sustained control of hemolysis and showed no signs of hypersplenism or iron overload. No splenic regrowth or infectious complications were observed. The major drawbacks of partial splenectomy are the increased risk of intra- and postoperative bleeding, splenic remnant torsion and splenic regrowth.
UNASSIGNED: Partial splenectomy is an alternative to total splenectomy for the treatment of adult β Thalassemia intermedia patients avoiding the risks associated with total splenectomy.
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