■精油(EO)由于其作为抗菌剂和抗炎剂的更广泛潜力,在治疗牙科疾病中具有相当大的治疗和预防作用。EO喜欢初榨椰子油,桉树油,薄荷油百里香油,丁香油,当组合使用时,可以进一步增强抗菌作用。然而,关于这些油组合使用时的协同作用的信息有限,特别是主要的牙周病原体牙龈卟啉单胞菌。
■本研究旨在比较市售EO对牙周病原体的抗菌功效,牙龈卟啉单胞菌,与氯己定(CHX)相比。
■在不同浓度下评估EO和CHX对牙周病原体牙龈卟啉单胞菌的抗菌功效。通过评价最小抑菌浓度(MIC)和最小杀菌浓度(MBC)。
■P.发现牙龈在100μg/ml的MIC和50μg/ml的EO浓度下敏感,这被认为是EO对牙龈卟啉单胞菌和CHX的MIC在0.4μg/ml时有效抑制微生物生长。
■EO的组合对牙龈卟啉单胞菌具有有效的抗菌活性,抗菌效果随着EO浓度的增加而增加。
UNASSIGNED: Essential oils (EOs) have a considerable amount of therapeutic and preventive effect in treating dental diseases due to their wider potential as antibacterial and anti-inflammatory agents. EOs like virgin coconut oil, eucalyptus oil, peppermint oil thyme oil, and clove oil, when used in combination, may further have enhanced antimicrobial effects. However, limited information exists on the synergistic effect of these oils when used in combination, especially on the primary periodontal pathogen Porphyromonas gingivalis.
UNASSIGNED: The current
study aims to compare the antimicrobial efficacy of commercially available EO on the periodontal pathogen, P. gingivalis, in comparison to chlorhexidine (CHX).
UNASSIGNED: Antimicrobial efficacy of EO and CHX was assessed at various concentrations against the periodontal pathogen P. gingivalis, by evaluating the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC).
UNASSIGNED: P. gingivalis was seen to be sensitive at a MIC of 100 μg/ml and 50 μg/ml concentration of the EO, which is regarded as the MIC of EO against P. gingivalis and CHX effectively inhibited microbial growth at 0.4 μg/ml.
UNASSIGNED: A combination of EOs possesses a potent antibacterial activity against P. gingivalis, and the antibacterial efficacy increases with increasing concentration of EOs.