■产后卵巢功能障碍[卵巢囊肿(OC)和持续性卵泡(PF)]一直是一个重要问题。寻找有效的激素治疗以改善奶牛的繁殖性能已成为必要。
■通过针对OC和PFs的特定定制治疗,改善产后奶牛的繁殖性能和卵巢活动。
■该研究包括48头母牛,在第14天P,它接受了两个剂量的500μgIM氯前列醇,间隔14天作为预同步方案。最后一次注射后14天进行超声卵巢扫描,持续4周。根据卵巢状态将奶牛分为三组:OC(n=14),PF(n=12),和NE(n=22)。在OC组,接受500μgIM氯前列醇和100μgIMcystoriline,14天后服用第二剂氯前列醇,36小时后服用第二剂贝司他林,和24小时后的AI(GnRH+PG/PG/GnRH)。在PF组中,装有孕酮释放阴道内装置(PRID)9天;同一天,他们接受了100μg的半胱氨酸,然后在7天后接受了500μg的氯前列醇,在PRID移除AI56小时后(PRID+GnRH/PG)。在NE组中,根据发情检测,进行人工授精至28天。
■卵巢活动受到定制治疗的极大影响,导致卵泡和黄体活动增强,特别是在PGF2α注射后。OC和PF组的发情反应分别为71.43%和75.02%,分别,在AI时间。而NE组排卵率为54.5%,妊娠率为31.8%,治疗组的生殖表现显着改善。OC和PF组的排卵率分别为71.43%和75%,第一次人工授精时的妊娠率分别为64.28%和66.7%。
■提高繁殖性能并最大程度地减少首次服务时间是对OC和PFs产后奶牛进行早期病例特异性治疗的可能优势。
UNASSIGNED: Postpartum ovarian dysfunction [ovarian cyst (OC) and persistent follicle (PF)] has been an important issue. Finding effective hormonal treatments to improve reproductive performance in dairy cows has become a necessity.
UNASSIGNED: Improve reproductive performance and ovarian activity in postpartum cows with specific customized treatment for OC and PFs.
UNASSIGNED: The study included 48 cows at 14 days P.P, which received two dosages of 500 μg IM cloprostenol, 14 days apart as presynchronization protocol. Ultrasound ovarian scans 14 days after the last injection for 4 weeks. The cows were divided into three groups according to ovarian status: OC (n = 14), PF (n = 12), and NE (n = 22). In the OC group, received 500 μg IM cloprostenol and 100 μg IM cystoriline, a second dose of cloprostenol 14 days later and a second dose of cystoriline 36 hours later, and AI after 24 hours (GnRH+ PG/PG/GnRH). In the PF group, was fitted with progesterone-releasing intravaginal device (PRID) for 9 days; the same day, they received 100 μg cystoreline then 500 μg cloprostenol 7 days later, after PRID removal AI 56 hours later (PRID + GnRH/PG). In the NE group, artificial insemination was implemented until 28 days depending on estrus detection.
UNASSIGNED: The ovarian activity was greatly affected by the customized treatments, leading to enhanced follicular and luteal activity, particularly after the PGF2α injection. The OC and PF groups showed substantial estrus responses of 71.43% and 75.02%, respectively, during AI time. While the NE group had an ovulation rate of 54.5% and a pregnancy rate of 31.8%, the treatment groups showed marked improvements in reproductive performance. The ovulation rates in the OC and PF groups were 71.43% and 75% and the pregnancy rates at the 1st artificial insemination were 64.28% and 66.7%.
UNASSIGNED: Improving reproductive performance and minimizing the time to first service are possible advantages of early case-specific treatment for postpartum cows with OC and PFs.