■马拉克斑病是一种罕见的炎症性疾病,通常发生在免疫受损的个体中,被认为是巨噬细胞杀菌缺陷的继发病。
方法:在本报告中,我们介绍了一例50岁的多胎患者,他出现了慢性盆腔疼痛.超声检查发现可疑的左外侧子宫肿块。腹腔镜探查显示子宫左侧附件有炎症肿块,腹膜,和中乙状结肠。该患者接受了全子宫切除术,双侧输卵管卵巢切除术和腹膜活检。组织学发现与malacopakia的左附件位置一致,细菌学分析显示大肠杆菌感染对环丙沙星敏感。在6个月的随访中,未观察到复发.手术和抗生素治疗后,患者的病情有所改善。
■泌尿生殖道硬斑多见于女性,没有特异性的临床,生物,或放射学特征。诊断基于组织学标准,特别是米迦勒-古特曼尸体的存在。我们对malakopakia病理生理学的理解的进步使得考虑药物治疗方案成为可能,主要通过使用抗生素。然而,在器官受到严重影响的情况下,建议手术切除。
结论:总结一下,附件软化斑是一种非常罕见的疾病,可能被误认为是恶性肿瘤。通过组织学检查确定诊断。通常的治疗方法是手术切除和靶向抗生素治疗相结合,因为通常直到手术后才做出诊断。
UNASSIGNED: Malakoplakia is a rare inflammatory condition that generally occurs in immunocompromised individuals and is thought to be secondary to a bactericidal defect in macrophages.
METHODS: In this report, we present the
case of a 50-year-old multiparous patient who presented with chronic pelvic pain. Ultrasonography revealed a suspicious left lateral-uterine mass. Laparoscopic exploration showed an inflammatory mass in the left adnexa adherent to the uterus, peritoneum, and meso-sigmoid. The patient underwent a total hysterectomy with bilateral salpingo-oophorectomy and peritoneal biopsy. Histological findings were consistent with a left adnexal location of malacopakia, and Bacteriological analysis revealed Escherichia coli infection sensitive to ciprofloxacin. At the 6-month follow-up, no recurrence was observed. The patient\'s condition improved following surgery and antibiotic treatment.
UNASSIGNED: Genitourinary malakoplakia is more common in women and has no specific clinical, biological, or radiological features. Diagnosis is based on histological criteria, notably the presence of Michaelis-Gutmann bodies. Advances in our understanding of the pathophysiology of malakoplakia have made it possible to consider medical treatment options, mainly through the use of antibiotics. However, in cases where the organ is severely affected, surgical excision is recommended.
CONCLUSIONS: To summarize, adnexal malacoplakia is a highly uncommon disease that may be mistaken as a malignant tumor. The diagnosis is established through histological examination. The usual treatment is a combination of surgical excision followed by targeted antibiotic therapy, as the diagnosis is often not made until after surgery.