Orthopedic infection

骨科感染
  • 文章类型: Case Reports
    人类sc疮是由Sarcoptesscabiei螨引起的传染性皮肤病,导致皮肤损伤和随后的机械刺激刮伤。这种受损的皮肤完整性使个体易于皮肤感染。虽然由金黄色葡萄球菌和化脓性链球菌引起的sc疮和皮肤感染之间的关联是有据可查的,关于此类病例中手术部位感染风险的文献有限.
    方法:本病例报告旨在探讨这一风险,该病例是一例在1例sc疮感染患者的复杂肘部损伤手术后由化脓性链球菌引起的手术部位感染。
    结论:镰刀菌感染导致细菌的直接传播,并有助于细菌感染。此外,由sc疮引起的补体抑制和菌群失调可能会促进这些细菌感染的发生。
    结论:皮肤感染经常发生在sc疮感染中。手术前应仔细评估首选切口。需要进一步的研究才能就此问题得出明确的结论。
    UNASSIGNED: Human scabies is a contagious skin condition caused by the Sarcoptes scabiei mite, leading to skin damage and subsequent mechanical irritation from scratching. This impaired skin integrity predisposes individuals to skin infections. While the association between scabies and skin infections caused by Staphylococcus aureus and Streptococcus pyogenes is well-documented, there is limited literature on the risk of surgical site infections in such cases.
    METHODS: This case report aims to explore this risk by presenting a case of surgical site infection caused by Streptococcus pyogenes following surgery for a complex elbow injury in a patient with scabies infestation.
    CONCLUSIONS: Scabies infestation leads to direct spread of bacteria and contributes to bacterial infection. Furthermore, complement inhibition and dysbiosis induced by the scabies may facilitate the occurrence of these bacterial infections.
    CONCLUSIONS: Skin infections are frequently encountered in scabies infestations. Preferred incision should be evaluated meticulously before surgery. Further studies are needed to reach a definitive conclusion on this subject.
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  • 文章类型: Review
    由毛孢菌引起的骨科真菌感染的报道极为稀少,因此,我们旨在描述一个案例系列,并回顾文献中发表的案例。如果以前的骨培养,关节或软组织对Trichosporon物种呈阳性,以及骨科感染的临床诊断。包括8名患者,在不同的骨科条件下,其中大多数是骨髓炎。主要的分离物种是Trichosporonasahii。所有患者均接受抗真菌药物治疗,主要是伏立康唑,和手术管理,导致较高的临床改善率和较低的相关死亡率。
    关于毛孢菌引起的骨科感染的报道很少。我们描述了由Trichosporon物种引起的一系列骨科感染病例,并回顾了以前发表的文献。我们观察到较高的临床改善率和较低的相关死亡率。
    Reports of orthopedic fungal infections caused by Trichosporon species are extremely scarce, thus we aimed to describe a case series and review the cases published in the literature. Patients were retrospectively included if a previous culture of bone, joint, or soft tissues had resulted positive for Trichosporon species along with a clinical diagnosis of an orthopedic infection. Eight patients were included with diverse orthopedic conditions, most of them cases of osteomyelitis. The main isolated species was Trichosporon asahii. All patients were treated with antifungals, mainly voriconazole, and surgical management, resulting in high rates of clinical improvement and low associated mortality.
    Reports of orthopedic infections caused by Trichosporon species are scarce. We described a case series of orthopedic infections caused by Trichosporon species and reviewed the previous published cases in the literature. We observed a high rate of clinical improvement and a low associated mortality.
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  • 文章类型: Journal Article
    OBJECTIVE: Shoulder arthroplasty (SA) has been performed by many years for the treatment of several conditions, including osteoarthritis and proximal humeral fractures following trauma. Surgical site infection (SSI) following Shoulder arthroplasty remains a challenge, contributing to increased morbidity and costs. Identification of risk factors may help implementing adequate strategies to prevent infection. We aimed to identify pre- and intra-operative risk factors associated with deep infections after Shoulder arthroplasty.
    METHODS: An unmatched case-control study was conducted to describe the prevalence, clinical and microbiological findings, and to evaluate patient and surgical risk factors for prosthetic shoulder infection (PSI), among 158 patients who underwent SA due to any reason, at a tertiary public university institution. Risk factors for PSI was assessed by uni- and multivariate analyses using multiple logistic regression.
    RESULTS: 168 SA from 158 patients were analyzed, with an overall infection rate of 9.5% (16/168 cases). Subjects undergoing SA with American Society of Anesthesiologists (ASA) grade III or higher (odds ratio [OR]=5.30, 95% confidence interval [CI]=1.58-17.79, p<0.013) and presenting local hematoma after surgery (odds ratio [OR]=7.10, 95% confidence interval [CI]=1.09-46.09, p=0.04) had higher risk for PSI on univariate analysis. However, only ASA score grade III or higher remained significant on multivariate analysis (OR=4.74, 95% CI=1.33-16.92, p=0.016). Gram-positive cocci and Gram-negative bacilli were equally isolated in 50% of cases; however, the most commonly detected bacterium was Pseudomonas aeruginosa (18.7%).
    CONCLUSIONS: This study provides evidence suggesting that patient-related known factors such as higher ASA score predisposes to shoulder arthroplasty-associated infection. Furthermore, unusual pathogens associated with PSI were identified.
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