由毛孢菌引起的骨科真菌感染的报道极为稀少,因此,我们旨在描述一个案例系列,并回顾文献中发表的案例。如果以前的骨培养,关节或软组织对Trichosporon物种呈阳性,以及骨科感染的临床诊断。包括8名患者,在不同的骨科条件下,其中大多数是骨髓炎。主要的分离物种是Trichosporonasahii。所有患者均接受抗真菌药物治疗,主要是伏立康唑,和手术管理,导致较高的临床改善率和较低的相关死亡率。
关于毛孢菌引起的骨科感染的报道很少。我们描述了由Trichosporon物种引起的一系列骨科感染病例,并回顾了以前发表的文献。我们观察到较高的临床改善率和较低的相关死亡率。
Reports of orthopedic fungal infections caused by Trichosporon species are extremely scarce, thus we aimed to describe a case series and
review the cases published in the literature. Patients were retrospectively included if a previous culture of bone, joint, or soft tissues had resulted positive for Trichosporon species along with a clinical diagnosis of an orthopedic infection. Eight patients were included with diverse orthopedic conditions, most of them cases of osteomyelitis. The main isolated species was Trichosporon asahii. All patients were treated with antifungals, mainly voriconazole, and surgical management, resulting in high rates of clinical improvement and low associated mortality.
Reports of orthopedic infections caused by Trichosporon species are scarce. We described a case series of orthopedic infections caused by Trichosporon species and reviewed the previous published cases in the literature. We observed a high rate of clinical improvement and a low associated mortality.