Oral lesions

口腔病变
  • 文章类型: Case Reports
    Tori是牙槽骨的反应性或发育性局部过度生长,不是癌性的。一个瘦,弱血管化的粘膜围绕着密集的皮质,低密度骨髓块称为托里或外生骨。Tori在中年时更常见。上颌骨(Toruspalatinus)和下颌骨(Torusmandibularis)都表现出Tori。说话困难和其他问题是与托里相关的常见障碍。Tori的直径范围从几毫米到几厘米。托里手术切除是治疗大托里妨碍言语的主要方法,咀嚼,或舌头的位置。以下病例研究包括一名36岁的男性患者,其下颌犬和前磨牙区域与骨生长有关。
    Tori are reactive or developmental localized overgrowths of alveolar bone that are not cancerous. A thin, weakly vascularized mucosa surrounds a densely cortical, low-density mass of bone marrow known as tori or exostosis. Tori are more frequently observed in middle age. Both the maxilla (torus palatinus) and the mandible (torus mandibularis) exhibit tori. Difficulty in speaking and other issues are common obstacles associated with tori. Tori range in diameter from a few millimeters to several centimeters. Surgical excision of tori is the mainstay of treatment for large tori obstructing speech, mastication, or tongue position. The following case study includes a 36-year-old male patient with an association of mandibular canine and premolar regions with bony outgrowth.
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  • 文章类型: Journal Article
    小儿口腔病理学包括影响儿童口腔的多种疾病和病症。在这项研究中,我们对沙特阿拉伯一个学术中心的数据集进行了分析,以调查儿科患者各种口腔病变的患病率。
    为了进行这项研究,我们分析了2012年1月至2022年12月期间在我们机构的口腔病理实验室接受活检的儿科患者(年龄范围:0-18岁)的口腔病理报告。我们收集的数据包括人口统计信息和诊断结果。进行统计分析以确定不同变量的患病率和相关性。
    该研究共分析了183例患有口腔疾病的儿科病例。观察到的最常见的情况是粘液囊肿(12%),根尖周围肉芽肿(7.7%),牙质囊肿(6.6%),和根性囊肿(6.6%)。一些情况显示,患病率因年龄和性别而异。例如,黏液囊肿在6-12岁的女性患者中更为普遍.
    这项回顾性研究为儿童口腔疾病的患病率和人口统计学特征提供了有价值的见解。通过了解该人群的患病率,并认识到与其他研究中引用的分布差异,我们强调了考虑区域和人口影响的重要性。需要进一步的前瞻性研究来调查可能导致这些变化的因素。
    UNASSIGNED: Pediatric oral pathology encompasses a wide range of diseases and conditions affecting the oral cavity in children. In this study we conducted an analysis on a dataset from one academic center in Saudi Arabia to investigate the prevalence of various oral lesions in pediatric patients.
    UNASSIGNED: To conduct this study we analyzed oral pathology reports of pediatric patients (age range: 0-18 years) who underwent biopsies at our institution\'s oral pathology laboratory between January 2012 and December 2022. The data we collected included demographic information and diagnostic findings. Statistical analysis was performed to determine the prevalence rates of and associations between different variables.
    UNASSIGNED: The study analyzed a total of 183 pediatric cases with oral pathologies. The most common conditions observed were mucocele (12 %), periapical granuloma (7.7 %), dentigerous cyst (6.6 %), and radicular cyst (6.6 %). Some conditions showed variations in prevalence based on age and gender. For example, mucoceles were more prevalent among patients who were 6-12 years of age and female.
    UNASSIGNED: This retrospective study provides valuable insights into the prevalence and demographic characteristics of pediatric oral pathologies. By understanding the prevalence of conditions in this population and recognizing differences in distribution compared with those cited in other studies, we highlighted the importance of considering regional and demographic influences. Further prospective studies are needed to investigate factors that may contribute to these variations.
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  • 文章类型: Journal Article
    进行口腔检查时,系统性疾病可能会出现早期症状。自从COVID-19大流行爆发以来,已经发表了几项研究,详细说明了该病毒对口腔的直接影响。本研究旨在确定感染严重急性呼吸道综合症冠状病毒2的个体与对照组之间的口咽表现是否确实存在任何显着差异,以及病毒是否有能力侵入口腔角质形成细胞和成纤维细胞,导致口腔溃疡和浅表病变的发展。本研究概述了疾病早期出现的症状,以及口腔最常受影响的区域,包括舌头,嘴唇,检查腭和口咽。在目前的回顾性研究中,4月之间招募了52名感染COVID-19的患者,2021年10月,2022年。此外,招募52名病毒检测呈阴性的个体作为对照组。该研究是通过全面检查并向所有参与者提供问卷进行的。结果显示,在接受检查的COVID-19组患者队列中(n=52),一个比例(平均,16.15)显示口腔表现。具体来说,COVID-19组中75%的患者描述口腔疼痛,这些患者中有69%的牙齿颜色或龋齿发生变化。总之,相对于对照组,与COVID-19组相比,口咽症状的患病率普遍较低,除了口腔疼痛(30.8%),扁桃体炎(17.3%),出血(34.6%),牙齿颜色变化(36.5%),复发(15.4%)和脓肿(7.7%)。因此,总的来说,无COVID-19的患者口腔表现较少.
    Systemic disorders may exhibit early signs when conducting an oral examination. Since the onset of the COVID-19 pandemic, several studies have been published detailing the direct impact of the virus on the oral cavity. The present study aimed to determine whether indeed there are any significant disparities in oropharyngeal manifestations between individuals infected with severe acute respiratory syndrome coronavirus 2 and a control group, and whether the virus has the ability to invade and reproduce inside oral keratinocytes and fibroblasts, resulting in the development of oral ulcerations and superficial lesions. The present study provides an overview of the symptoms that occur at an early stage of the illness, and the most commonly affected regions of the oral cavity, including the tongue, lips, palate and oropharynx are examined. In the present retrospective study, 52 patients infected with COVID-19 were recruited between April, 2021 and October, 2022. In addition, 52 individuals who tested negative for the virus were recruited as the control group. The study was conducted through a thorough examination and questionnaire provided to all participants. The results revealed that among the cohort of patients from the COVID-19 group examined (n=52), a proportion (mean, 16.15) displayed oral manifestations. Specifically, 75% of the patients in the COVID-19 group described oral cavity pain, and 69% of these patients had changes in teeth color or dental caries. In summary, in relation to the control group, the prevalence of oropharyngeal symptoms was generally lower compared to the COVID-19 group, apart from oral cavity pain (30.8%), tonsillitis (17.3%), bleeding (34.6%), teeth color changes (36.5%), recurrence (15.4%) and abscesses (7.7%). Thus, on the whole, the patients without COVID-19 had fewer oral manifestations.
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  • 文章类型: Journal Article
    烟草主要作为吸烟或无烟烟草消费[SLT]。“无烟烟草”(SLT)术语用于以咀嚼形式消费与其他成分混合的烟草,随地吐痰和蘸水。无烟烟草的消费者咀嚼产品并吐出在口腔中积聚的汁液,这导致口腔的各种恶性和恶性前病变。
    描述性观察研究是通过耳鼻喉科在焦特布尔市进行的,头颈部手术,SN医学院博士,焦特布尔.
    无烟烟草的男女比例几乎相同。年龄的增加与口腔病变的发生有关,在年龄>64岁的组中,有43%的患者发生了口腔病变。持续时间是另一个相关因素,66%的人在使用<10年内出现症状。口腔粘膜下纤维化是最常见的病变。0.3%为恶性病变。大约78%的病例发展了依赖性。糖尿病患者更容易出现口腔病变。
    无烟烟草在口腔中的病变发展取决于各种因素,例如每天的烟草使用量,放烟草的地方和持续时间。了解其致命影响并及时诊断和管理可以挽救许多生命。
    UNASSIGNED: Tobacco is consumed mainly as smoking or smokeless tobacco [SLT]. \"Smokeless tobacco\" (SLT) term is used for the consumption of tobacco mixed with other constituents in form of chewing, spitting and dipping. Consumers of smokeless tobacco chew the products and spit out the juice that builds up in oral cavity which leads to various malignant and pre malignant lesions of oral cavity.
    UNASSIGNED: Descriptive observational study was conducted in the city of Jodhpur through department of ENT, Head & Neck Surgery, Dr. SN medical college, Jodhpur.
    UNASSIGNED: Male to female ratio of smokeless tobacco usage was almost same. Increasing age was associated with occurrence of oral lesions and 43% patients developed oral lesions in the group > 64 yrs of age. Duration was another associating factor and 66% developed symptoms within < 10 years of usage. Oral submucous fibrosis is the most common lesion. Malignant lesions were seen in 0.3% cases. Around 78% cases developed dependency. Diabetic patients were seen more prone to development of oral lesions.
    UNASSIGNED: Development of lesions in the oral cavity by smokeless tobacco depends on various factors such as quantity of tobacco usage per day, place of putting tobacco and duration. Awareness regarding its fatal effects and timely diagnosis and management can save many lives.
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  • 文章类型: Journal Article
    背景:义齿引起的口腔病变(DIOLs)通常在放置或调整新的或重新对齐的义齿后不久出现,经常导致严重的疼痛和不适。
    目的:本研究旨在对DIOLs进行分类,特别强调评估相关疼痛。
    方法:在Hadassah牙科医学院进行了一项前瞻性案例研究,涉及126名患者,这些患者共安装了193个各种类型的假牙。所有患者在义齿交付后1-8周内接受了全面的口腔内检查,完成症状问卷并审查其医疗记录.记录的关键变量包括年龄,性别,整体健康状况,义齿类型,和DIOL的详细描述。描述包括病变位置等因素,形状,颜色,尺寸,边界特征,溃疡性外观,膜覆盖率,3D形态学(升高,浸入和平坦)和患者报告的言语疼痛评分(VPS),当触摸DIOL时,戴假牙的时候,和不戴假牙的时候。
    结果:值得注意的是,25.4%的义齿佩戴者不需要调整,而14.4%的人需要三次以上的修订。大多数(71.8%)的DIOLs病例与下颌全口义齿有关,主要位于牙槽脊。平均VPS表明疼痛强度为7±2.1,两个颌骨中的临时假牙引起的不适最多。种植体支撑的覆盖义齿在下颌骨中放置时特别疼痛。此外,在老年人和有假肢经验的人中,VPS得分较高。观察到疼痛强度与慢性健康状况之间存在显着相关性(0.036)。
    结论:这项研究揭示了DIOL的独特特征,并强调了DIOL发展后疼痛的多因素性质。对患者和义齿特征对DIOL和疼痛强度的影响的见解可以指导医疗保健专业人员优化患者的舒适度和满意度。
    BACKGROUND: Denture-induced oral Lesions (DIOLs) often manifests shortly after the placement or adjustment of new or realigned dentures, frequently resulting in severe pain and discomfort.
    OBJECTIVE: This study aimed to classify DIOLs placing a particular emphasis on assessing the associated pain.
    METHODS: A prospective case study was conducted involving 126 patients who were fitted with a total of 193 dentures of various types at the Hadassah School of Dental Medicine. All patients underwent comprehensive intra-oral examinations within 1-8 weeks following denture delivery, completed symptom questionnaires and had their medical records reviewed. Key variables documented included age, gender, overall health status, denture type, and a detailed description of the DIOLs. The description encompassed factors such as lesion location, shape, colour, size, border characteristics, ulcerative appearance, membrane coverage, 3D morphology (elevated, immersed and flat) and patient-reported Verbal Pain Score (VPS) when touching the DIOLs, when wearing the denture, and when not wearing the denture.
    RESULTS: Notably, 25.4% of denture wearers required no adjustments, while 14.4% necessitated more than three revisions. A majority (71.8%) of DIOLs cases were associated with mandibular complete dentures, primarily situated on the alveolar ridge. The mean VPS indicated a pain intensity of 7 ± 2.1, with temporary dentures in both jaws causing the most discomfort. Implant-supported overdentures were particularly painful when placed in the mandible. Additionally, VPS scores were higher among older individuals and those with prior prosthetic experiences. A significant correlation was observed between pain intensity and presence of chronic health condition (0.036).
    CONCLUSIONS: This study revealed distinct characteristics of DIOLs and highlighted the multifactorial nature of pain experienced following the development of DIOLs. Insights into the influence of patient and denture characteristics on DIOLs and pain intensity can guide healthcare professionals in optimising patient comfort and satisfaction.
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  • 文章类型: Journal Article
    背景:Teledentic是一种新兴的工具,用于交换医疗信息和临床图像以促进诊断,预防,以及口腔疾病的治疗以及患者的保证和教育。考虑到沙特阿拉伯口腔医学专家的短缺,这项研究旨在评估牙科专家在远程口服药方面的经验及其在解决这一短缺方面的潜在适用性。
    方法:这是一个试点项目,从2020年1月至2020年3月在口腔医学领域的专家中进行的横断面研究。共有16例预选的口腔病变,包括临床病史和图像,被开发,已验证,并通过电子邮件与研究参与者分享。每个病例都包括鉴别诊断问题,临时诊断,和管理。记录了回复,分析,并以平均值和百分比表示。
    结果:共有49名受试者参与了这项研究,超过一半的受试者年龄在40岁以下,三分之二为女性。共有23名参与者有远程口服药的经验,主要通过WhatsApp(95.7%),这些病例来自患者,他们的家人,朋友,或其他牙医。对于所有研究案例,正确的诊断分数在73.50到100%之间,正确的管理在51%到98%之间。
    结论:远程口腔医疗是一种有效的工具,可能在口腔医学服务短缺的农村地区的患者管理中发挥重要作用。有必要进行更大样本量的进一步研究,并与国际中心合作,以证实这些发现。
    BACKGROUND: Teledentistry is an emerging tool to exchange medical information and clinical images to facilitate the diagnosis, prevention, and treatment of oral diseases and patient assurance and education. Considering the shortage of oral medicine specialists in Saudi Arabia, this study aims to assess the experiences of dental specialists with tele-oral medicine and its potential applicability in addressing this shortage.
    METHODS: This was a pilot, cross-sectional study conducted among specialists in the field of oral medicine from January 2020 to March 2020. A total of 16 preselected cases with oral lesions, including clinical history and images, were developed, validated, and shared via email with study participants. Each case included questions on differential diagnosis, provisional diagnosis, and management. The responses were recorded, analyzed, and presented as means and percentages.
    RESULTS: A total of 49 subjects participated in this study and more than half were under 40 years of age and two-thirds were women. A total of 23 participants had prior experience with tele-oral medicine, mainly via WhatsApp (95.7%), and these cases were received from patients, their families, friends, or other dentists. For all study cases, the correct diagnosis score ranged between 73.50 and 100%, and correct management ranged between 51 and 98%.
    CONCLUSIONS: Tele-oral medicine is an effective tool that may play an important role in patient management in rural regions with a shortage of oral medicine services. Further studies with larger sample sizes and in collaboration with international centers are warranted to confirm these findings.
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  • 文章类型: Journal Article
    背景:副孢子菌病是拉丁美洲最普遍的全身性真菌病,在巴西发病率很高,哥伦比亚和委内瑞拉,并构成严重的公共卫生问题,工作中常见的发病和残疾原因。细胞死亡的一些机制被描述为感染过程中的重要工具。当细胞凋亡被阻断时,RIPK(受体相互作用蛋白激酶)3依赖性,一种不依赖caspase的细胞死亡形式,可以限制病原体的复制和传播。一些介导坏死性凋亡的分子包括RIPK3,并且由于其信号传导机制和病理功能而被广泛研究。RIPK3激活NLRP1和NLRP3介导的炎性小体形成。Caspase-1在将细胞因子ILβ和IL18加工成它们的活性形式中具有重要作用。这些分子是炎症小体表征的一部分,其依赖caspase-1的激活促进了焦化细胞的死亡和促炎细胞因子的分泌。了解病原体介导的细胞死亡机制有助于了解感染和炎症的发病机理。
    目的:这项工作的目的是通过免疫组织化学方法和RIPK-3,IL1β的鉴定,确定人副角菌病口腔粘膜病变中程序性细胞死亡和炎症体成分的机制。IL18、NLRP-1和胱天蛋白酶-1。包括30个标本,使用苏木精-伊红染色对病变进行组织病理学分析。
    结果:我们关于炎症小体元件的原位表达和程序性细胞死亡的结果显示IL-1β的表达增加,NLRP-1、胱天蛋白酶-1和RIPK-3。我们建议炎性体复合物与RIPK3相互作用,参与副角菌病口腔病变的免疫发病机制。
    BACKGROUND: Paracoccidioidomycosis is the most prevalent systemic mycosis in Latin America, with a high incidence in Brazil, Colombia and Venezuela, and constitutes a serious public health problem, a frequent cause of morbidity and disability for work. Some mechanisms of cell death are described as important tools in infectious processes. When apoptosis is blocked, RIPK (Receptor-interacting protein kinase) 3 dependent, a caspase-independent form of cell death, can limit the replication and spread of pathogens. Some molecules that mediate necroptosis include RIPK3 and have been extensively studied due to their signalling mechanism and pathological function. RIPK3 activates NLRP1 and NLRP3-mediated inflammasome formation. Caspase-1 has an important role in processing the cytokines ILβ and IL18 to their active form. Such molecules are part of the inflammasome characterization, whose caspase-1-dependent activation promotes the death of pyroptotic cells and the secretion of proinflammatory cytokines. Knowledge about the mechanisms of pathogen-mediated cell death can be useful for understanding of the pathogenesis of infections and inflammatory conditions.
    OBJECTIVE: The objective of this work was to identify the mechanisms of programmed cell death and inflammasome components in human oral mucosal lesions of paracoccidioidomycosis through immunohistochemical methods and identification of RIPK-3, IL1β, IL18, NLRP-1 and caspase-1. Thirty specimens were included, and a histopathological analysis of the lesions was performed using haematoxylin-eosin staining.
    RESULTS: Our results on in situ expression of inflammasome elements and programmed cell death showed increased expression of IL-1β, NLRP-1, caspase-1 and RIPK-3. We suggest that inflammasome complex participate in the immunopathogenesis in paracoccidioidomycosis oral lesions in an interplay with RIPK3.
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  • 文章类型: Journal Article
    这项研究的目的是确定一般病理学家对口腔病理学的感知程度,以及在诊断挑战中利用口腔病理学家协助识别口腔病变的需求。
    在合格的普通病理学家中进行了问卷调查,以收集数据。调查项目集中在各个方面,包括口腔病理学作为一个专业的分析,在诊断挑战中聘请口腔病理学家识别口腔病变的重要性,以及处理此类病变时遇到的困难。收集的数据使用描述性和推理统计学进行分析。为了比较工作经验与牙源性囊肿和肿瘤病例的转诊之间的关系,采用卡方检验。显著性水平p﹤0.05被认为是有统计学意义的。
    二百五十名普通病理学家回答了问卷。两百三十二名(92.8%)参与者表现出对口腔病理学的认识。对于口腔的诊断,下巴,唾液腺病理性病变,大多数198名(79.2%)受访者认为需要口腔病理学家进行诊断。关于将病变转诊给口腔病理学家,137(54.8%),参与者没有提及。在口腔病理学的训练方面,所有参与者都同意他们将在口腔病理学中进行短期发布。对于具有挑战性的案件,所有普通病理学家都认为口腔病理学家应该是团队的一部分。
    普通病理学家认为口腔病理学是一个专业,并认为在诊断中需要口腔病理学家的意见。然而,大多数普通病理学家没有将复杂的病例转介给口腔病理学家。因此,鼓励口腔病理学家及其在诊断复杂头颈部病例的组织病理学实验室的聘用至关重要。
    UNASSIGNED: The objective of this study was to identify the degree of perception of oral pathology as a specialty among the general pathologists and the need of utilizing oral pathologists in assisting to identify oral lesions in diagnostic challenges.
    UNASSIGNED: A questionnaire-based survey was conducted among qualified general pathologists to collect the data. The survey items focused on various aspects, including the analysis of oral pathology as a specialty, the importance of employing oral pathologists for identifying oral lesions in diagnostic challenges, and the difficulties encountered in managing such lesions. The data collected was analyzed using descriptive and inferential statistics. For comparing the relationship between work experience and the referral of odontogenic cysts and tumors cases, a Chi-square test was employed. A significance level of p ⩽ 0.05 was deemed as statistically significant.
    UNASSIGNED: Two hundred and fifty general pathologists responded to the questionnaire. Two hundred and thirty two (92.8%) participants showed awareness of oral pathology as a specialty. For the diagnosis of oral, jaws, and salivary glands pathologic lesions, the majority 198 (79.2%) respondents believed that oral pathologists are required for the diagnosis. Regarding the referrals of lesions to oral pathologists, 137 (54.8%), participants did not refer. In terms of training in oral pathology, all of the participants agreed that they would undertake short-term posting in oral pathology. For challenging cases, all the general pathologists believed that oral pathologists should be part of the team.
    UNASSIGNED: The general pathologists recognized oral pathology as a specialty and feel the need for an oral pathologist opinion in diagnosis. However, most of the general pathologists did not refer the complex cases to oral pathologists. Therefore, it is of paramount importance to encourage oral pathologists and their hiring at histopathology laboratories that are diagnosing complex head and neck cases.
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  • 文章类型: Journal Article
    无烟烟草,以及槟榔,导致口腔癌变和癌前病变。印度的传统价值,以及西孟加拉邦不允许女性吸烟,但是没有人反对使用无烟烟草或槟榔。地理和社会文化,西孟加拉邦的北部与南部不同。
    本研究旨在评估不同咀嚼习惯的患病率,习惯产品,西孟加拉邦两个社会文化不同地区的女性与习惯相关的不同口腔病变。
    选择了来自北孟加拉地区的222名妇女和来自南孟加拉地区的173名15岁及以上的妇女。使用结构化问卷进行了面对面访谈。进行口腔检查以排除任何由致癌习惯引起的口腔粘膜改变。
    卡方检验或Fischer\的精确检验用于酌情比较不成对比例。
    在孟加拉北部地区,42.34%的女性是咀嚼者,在孟加拉南部地区,18.50%的女性是咀嚼者。年轻的女性咀嚼者更多来自孟加拉北部地区。女人,居住在孟加拉北部的不同地区有更多的与习惯相关的口腔病变,与孟加拉南部相比。
    应特别注意提高女性对咀嚼习惯相关健康危害的认识,尤其是在北孟加拉地区。
    UNASSIGNED: Smokeless tobacco, as well as areca-nut both, causes cancerous and precancerous lesions of the oral cavity. The traditional value of India, as well as West Bengal do not allow females for smoking, but there is no such disapproval for using smokeless tobacco or areca nut. Geographically and socio-culturally, the Northern part of West Bengal differs from its Southern part.
    UNASSIGNED: This study aimed to assess the prevalence of different chewing habits, habit products, and habit-related different oral lesions among females in two socio-culturally different areas of West Bengal.
    UNASSIGNED: A total of 222 women from areas of North Bengal and 173 women from areas of South Bengal aged 15 years and above were selected. A face-to-face interview was conducted using a structured questionnaire. An oral cavity examination was done to rule out any oral mucosal alterations caused by cancer-causing habits.
    UNASSIGNED: Chi-square test or Fischer\'s exact tests were used to compare unpaired proportions as appropriate.
    UNASSIGNED: In areas of the northern part of Bengal, 42.34% of females were chewers, and in areas of the southern part of Bengal 18.50% of females were chewers. Younger female chewers were more from areas of the northern part of Bengal. Women, residing in different areas of the northern part of Bengal had more habit-related oral lesions, compared to the southern part of Bengal.
    UNASSIGNED: Special attention should be given to increasing awareness regarding chewing habit-related health hazards among females, especially in areas of North Bengal.
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  • 文章类型: Journal Article
    使用鼻烟,一个潮湿的,无烟烟草产品,可能导致鼻烟放置区域的口腔粘膜局部变化。它还可以导致不可逆的牙龈回缩。这项横断面研究旨在调查使用鼻烟之间的关系,挪威青少年口腔粘膜病变(鼻烟引起的病变)和牙龈退缩。
    所有在2015年10月至2016年12月期间在挪威东南部地区就诊的18-20岁青少年均应邀参加。所有参与者(n=1363)在临床检查前填写电子问卷。其中,216每天使用鼻烟。
    在使用参与者的每日鼻烟中观察到79.2%的鼻烟诱导的病变。在调整后的回归分析中,与较不严重的病变相比,1个月内每增加1盒鼻烟,出现更严重病变的几率为1.12倍(p<.01).女性患严重病变的可能性比男性低46%(p=0.03)。在18.4%的参与者中观察到牙龈缩回。每年使用鼻烟,牙科退缩的几率显着提高了34%。
    大多数使用鼻烟的青少年有鼻烟诱导的病变,而大约五分之一有牙龈退缩。病变的严重程度和牙龈回缩随着鼻烟盒的使用量和鼻烟使用的持续时间而增加,分别。
    UNASSIGNED: Use of snus, a moist, smokeless tobacco product, may lead to local changes in the oral mucous membrane in the area where the snus is placed. It can also cause irreversible gingival retraction. This cross-sectional study aimed to investigate the relationship between use of snus, oral mucosal lesions (snus induced lesions) and gingival retractions among adolescents in Norway.
    UNASSIGNED: All 18-20 years olds visiting public dental health clinics in the south-eastern region of Norway between October 2015 and December 2016 were invited to participate. All participants (n = 1363) filled in an electronic questionnaire before a clinical examination. Of these, 216 used snus daily.
    UNASSIGNED: Snus induced lesions were observed in 79.2% of daily snus using participants. In adjusted regression analyses, the odds of having a more severe lesion as opposed to a less severe lesion were 1.12 times greater for each additional box of snus used in a month (p < .01). Women were 46% less likely to have a severe lesion than men (p = .03). Gingival retractions were observed in 18.4% of the participants. The odds for dental retraction were significantly higher by 34% for each year of snus use.
    UNASSIGNED: Most of the adolescents using snus had snus induced lesions, whereas approximately one-fifth had gingival retractions. The severity of the lesion and gingival retraction increased with the amount of snus boxes used and the duration of the snus use, respectively.
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