■这项研究旨在通过将人工智能(AI)应用于眼底图像来自动和定量分析视盘的特征。
■这项横断面研究共招募了1084名本科生。视神经盘区域,杯盘比(C/D),光盘倾斜,和该地区,宽度,使用AI自动定量检测乳头周围萎缩(PPA)的高度。基于轴向长度(AL),参与者分为5组:第1组(AL≤23mm);第2组(23mm
■共999名本科生被纳入分析。视盘倾斜和PPA的患病率分别为47.1%和92.5%,分别,并随着近视的严重程度而增加。平均视盘面积,PPA区域,C/D,和视盘倾斜比分别为1.97±0.46mm2、0.84±0.59mm2、0.18±0.07和0.81±0.08。在第5组中,平均视盘面积(1.84±0.41mm2)和视盘倾斜比(0.79±0.08)明显小于其他组,PPA面积(1.12±0.61mm2)明显大于其他组。AL与视盘面积和视盘倾斜率呈负相关(r=-0.271,-0.219;均p<0.001),与PPA面积呈正相关,宽度,和身高(r=0.421,0.426,0.345;所有p<0.01)。较大的AL(β=0.284,p<0.01)和较小的视盘倾斜比(β=-0.516,p<0.01)与较大的PPA面积有关。
■使用AI可以合理,有效地提取视盘的特征。视盘的量化可能为临床医生评估近视程度提供新的指标。
UNASSIGNED: This study aimed to automatically and quantitatively analyse the characteristics of the optic disc by applying artificial intelligence (AI) to fundus images.
UNASSIGNED: A total of 1084 undergraduates were recruited in this cross-sectional study. The optic disc area, cup-to-disc ratio (C/D), optic disc tilt, and the area, width, and height of peripapillary atrophy (PPA) were automatically and quantitatively detected using AI. Based on axial length (AL), participants were divided into five groups: Group 1 (AL ≤ 23 mm); Group 2 (23 mm < AL≤ 24 mm); Group 3 (24 mm < AL≤ 25 mm); Group 4 (25 mm < AL< 26 mm) and Group 5 (AL ≥ 26 mm). Relationships between ocular parameters and optic disc characteristics were analysed.
UNASSIGNED: A total of 999 undergraduates were included in the analysis. The prevalence of optic disc tilting and PPA were 47.1% and 92.5%, respectively, and increased with the severity of myopia. The mean optic disc area, PPA area, C/D, and optic disc tilt ratio were 1.97 ± 0.46 mm2, 0.84 ± 0.59 mm2, 0.18 ± 0.07, and 0.81 ± 0.08, respectively. In Group 5, the average optic disc area (1.84 ± 0.41 mm2) and optic disc tilt ratio (0.79 ± 0.08) were significantly smaller and the PPA area (1.12 ± 0.61 mm2) was significantly larger than those in the other groups. AL was negatively correlated with optic disc area and optic disc tilt ratio (r=-0.271, -0.219; both p < 0.001) and positively correlated with PPA area, width, and height (r = 0.421, 0.426, 0.345; all p < 0.01). A greater AL (β = 0.284, p < 0.01) and a smaller optic disc tilt ratio (β=-0.516, p < 0.01) were related to a larger PPA area.
UNASSIGNED: The characteristics of the optic disc can be feasibly and efficiently extracted using AI. The quantization of the optic disc might provide new indicators for clinicians to evaluate the degree of myopia.