Oligella ureolytica

  • 文章类型: Case Reports
    解脲大肠杆菌是一种革兰氏阴性杆菌,alcaligenaceae家族的成员,以前从未被报道为致命的。在这里,据报道,一名怀疑患有膀胱癌的老年妇女中,由溶尿Oligella引起的致命感染病例。通过细菌16SrRNA序列的Sanger测序确认了物种鉴定,并将其与已发表的序列进行系统发育分析。开始使用头孢曲松和苯唑西林的初始抗生素治疗,但由于耐药性而不得不转换。头孢吡肟联合甲硝唑给药,不幸的是未能阻止病人的死亡。需要进一步的研究来探索影响溶尿Oligella感染临床结局的其他因素。
    Oligella ureolytica is a Gram-negative bacillus, a member of the Alcaligenaceae family, that had never previously been reported as lethal. Herein, a case of fatal infection caused by Oligella ureolytica in an elderly woman with suspected bladder cancer is reported. The species identification was confirmed through Sanger sequencing of the bacterial 16S rRNA sequence and compared to published sequences for phylogenetic analysis. Initial antibiotic therapy with ceftriaxone and oxacillin was initiated but had to be switched due to resistance. Cefepime in combination with metronidazole was administered, unfortunately failing to prevent the patient\'s death. Further studies are needed to explore additional factors influencing clinical outcomes in Oligella ureolytica infections.
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  • 文章类型: Case Reports
    Oligella是人类泌尿道的共生菌属,很少引起临床感染。我们报告了一名无症状的24岁男性,有Tourette综合征病史,并且最近放置了深部脑刺激器导线,在硬件植入过程中发现与Oligella物种共感染。这是第一例报道的Oligella深部脑刺激器感染病例,一种潜在的认识不足和新兴的机会细菌。我们回顾了先前发表的泌尿生殖道外Oligella感染病例,并详细介绍了这种罕见病原体的临床管理。
    Oligella is a commensal bacteria genus of the human urinary tract that rarely precipitates clinical infections. We report the case of an asymptomatic 24-year-old male with a medical history of Tourette syndrome and the recent placement of deep brain stimulator leads, which were found to be co-infected with Oligella species during hardware implantation. This is the first reported case of a deep brain stimulator infection by Oligella, a potentially under-recognized and emerging opportunistic bacteria. We review the previously published cases of extra-genitourinary Oligella infections and detail the clinical management of this uncommon pathogen.
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  • 文章类型: Case Reports
    A case of Oligella ureolytica infection of a cervical lymph node is presented and previous cases of oligella infection reported in the literature are reviewed. Underlying malignancy and urinary tract obstruction were observed in many of the cases. All patients responded to antimicrobial therapy and, in those cases associated with urinary tract obstruction, surgical relief of the obstruction. The microbiology and clinical features of oligella infections are reviewed.
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