Nitrogen dioxide (NO2)

二氧化氮 (NO2)
  • 文章类型: Journal Article
    目前的证据表明,空气中的污染物通过出现小于胎龄(SGA)或足月低出生体重(TLBW)对胎儿生长产生不利影响。该研究的目的是批判性地评估有关环境污染与SGA或TLBW发生率之间关联的现有文献。在Pubmed/MEDLINE进行了全面的文献检索,WebofScience,科克伦图书馆,EMBASE,和谷歌学者使用预定义的纳入和排除标准。该方法符合PRISMA准则。系统评价方案在PROSPERO注册,ID号:CRD42022329624。因此,69篇选定的论文描述了环境污染物对SGA和TLBW发生的影响,颗粒物≤10μm(PM10)的赔率(ORs)为1.138,颗粒物≤2.5μm(PM2.5)为1.338,1.173代表臭氧(O3),1.287二氧化硫(SO2),一氧化碳(CO)为1.226。分析的所有8项研究都验证了暴露于挥发性有机化合物(VOCs)是SGA或TLBW的危险因素。SGA发生的高危人群中的孕妇,即,那些生活在城市地区或接近污染源的人,并发症的风险增加。了解孕妇的确切暴露时间有助于改善产前护理和对SGA胎儿的及时干预。然而,我们的研究结果中强调的普遍空气污染表明,迫切需要在日常生活中采取适应性措施来减轻全球环境污染。
    Current evidence suggests that airborne pollutants have a detrimental effect on fetal growth through the emergence of small for gestational age (SGA) or term low birth weight (TLBW). The study\'s objective was to critically evaluate the available literature on the association between environmental pollution and the incidence of SGA or TLBW occurrence. A comprehensive literature search was conducted across Pubmed/MEDLINE, Web of Science, Cochrane Library, EMBASE, and Google Scholar using predefined inclusion and exclusion criteria. The methodology adhered to the PRISMA guidelines. The systematic review protocol was registered in PROSPERO with ID number: CRD42022329624. As a result, 69 selected papers described the influence of environmental pollutants on SGA and TLBW occurrence with an Odds Ratios (ORs) of 1.138 for particulate matter ≤ 10 μm (PM10), 1.338 for particulate matter ≤ 2.5 μm (PM2.5), 1.173 for ozone (O3), 1.287 for sulfur dioxide (SO2), and 1.226 for carbon monoxide (CO). All eight studies analyzed validated that exposure to volatile organic compounds (VOCs) is a risk factor for SGA or TLBW. Pregnant women in the high-risk group of SGA occurrence, i.e., those living in urban areas or close to sources of pollution, are at an increased risk of complications. Understanding the exact exposure time of pregnant women could help improve prenatal care and timely intervention for fetuses with SGA. Nevertheless, the pervasive air pollution underscored in our findings suggests a pressing need for adaptive measures in everyday life to mitigate worldwide environmental pollution.
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  • 文章类型: Systematic Review
    越来越多的证据表明间质性肺病(ILD)与空气污染之间存在因果关系,都是为了疾病的发展,并推动疾病进展。我们的目标是提供关于空气污染之间关联的全面文献综述,ILD,包括特发性肺纤维化(IPF)。
    我们从六个在线数据库中进行了系统搜索。两名独立作者(DL和CF)选择了研究,并使用纽卡斯尔-渥太华量表(NOS)严格评估了偏倚的风险。研究结果通过叙事综合和荟萃分析呈现。当至少有三项研究检查相同的污染物-健康结果对时,仅进行荟萃分析。所有评估污染物浓度的等效增量,使用随机效应模型。
    确定了在13个国家或地区进行的24项观察性研究。正在调查的污染物包括臭氧(O3),二氧化氮(NO2),直径为10微米或更小(PM10)和2.5微米或更小(PM2.5)的颗粒物,二氧化硫(SO2),一氧化碳(CO),一氧化氮(NO)和氮氧化物(NOx)。我们进行了荟萃分析,以评估急性加重(AE)-IPF的估计风险比(RR)与暴露于空气污染物浓度每增加10μg/m3有关。包括O3、NO2、PM10和PM2.5。荟萃分析显示,PM2.5中AE-IPF的风险增加之间存在显着关联,RR为1.94(95%CI1.30-2.90;p=0.001)。所有纳入研究的结果表明,暴露于空气污染物的增加可能与ILD患者的一系列健康问题有关。
    关于空气污染物和ILD关系的现有研究的匮乏强调了在该领域进行进一步全面研究的必要性。现有数据表明,降低大气中PM2.5的水平可能会降低ILD患者的AE频率和严重程度。
    UNASSIGNED: There is a growing body of evidence suggesting a causal relationship between interstitial lung disease (ILD) and air pollution, both for the development of the disease, and driving disease progression. We aim to provide a comprehensive literature review of the association between air pollution, and ILD, including idiopathic pulmonary fibrosis (IPF).
    UNASSIGNED: We systematically searched from six online database. Two independent authors (DL and CF) selected studies and critically appraised the risk of bias using the Newcastle-Ottawa Scale (NOS). Findings are presented through a narrative synthesis and meta-analysis. Meta-analyses were performed exclusively when there was a minimum of three studies examining identical pollutant-health outcome pairs, all evaluating equivalent increments in pollutant concentration, using a random effects model.
    UNASSIGNED: 24 observational studies conducted in 13 countries or regions were identified. Pollutants under investigation encompassed ozone (O3), nitrogen dioxide (NO2), Particulate matter with diameters of 10 micrometers or less (PM10) and 2.5 micrometers or less (PM2.5), sulfur dioxide (SO2), carbon monoxide (CO), nitric oxide (NO) and nitrogen oxides (NOx). We conducted meta-analyses to assess the estimated Risk Ratios (RRs) for acute exacerbations (AE)-IPF in relation to exposure to every 10 μg/m3 increment in air pollutant concentrations, including O3, NO2, PM10, and PM2.5. The meta-analysis revealed a significant association between the increased risk of AE-IPF in PM2.5, yielding RR 1.94 (95% CI 1.30-2.90; p = 0.001). Findings across all the included studies suggest that increased exposure to air pollutants may be linked to a range of health issues in individuals with ILDs.
    UNASSIGNED: A scarcity of available studies on the air pollutants and ILD relationship underscores the imperative for further comprehensive research in this domain. The available data suggest that reducing levels of PM2.5 in the atmosphere could potentially reduce AE frequency and severity in ILD patients.
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  • 文章类型: Journal Article
    Owing to the excellent sensitivity to gases, metal-oxide semiconductors (MOS) are widely used as materials for gas sensing. Usually, MOS gas sensors have some common shortages, such as relatively poor selectivity and high operating temperature. Graphene has drawn much attention as a gas sensing material in recent years because it can even work at room temperature, which reduces power consumption. However, the low sensitivity and long recovery time of the graphene-based sensors limit its further development. The combination of metal-oxide semiconductors and graphene may significantly improve the sensing performance, especially the selectivity and response/recovery rate at room temperature. In this review, we have summarized the latest progress of graphene/metal-oxide gas sensors for the detection of NO2, NH3, CO and some volatile organic compounds (VOCs) at room temperature. Meanwhile, the sensing performance and sensing mechanism of the sensors are discussed. The improved experimental schemes are raised and the critical research directions of graphene/metal-oxide sensors in the future are proposed.
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