Neurodevelopmental disability

神经发育障碍
  • 文章类型: Journal Article
    儿科前流口水对儿童和护理人员的日常生活有重大影响。A型肉毒神经毒素(BoNT-A)注射被认为是减少流口水的有效治疗方法。然而,对于应注射哪些主要唾液腺以获得最佳治疗效果,同时将副作用的风险降至最低,国际上尚无共识。这项范围审查旨在探索颌下注射BoNT-A和同时进行颌下和腮腺(即四腺)注射的证据,分别,并评估是否可以在不同研究中比较结局,以改善关于儿科前流口性最佳初始BoNT-A治疗方法的决策。PubMed,Embase,搜索和WebofScience以确定有关颌下或四腺注射BoNT-A治疗神经发育障碍儿童前流口性的相关研究(直到2023年10月1日)。治疗上的异同,病人,结果,并评估随访特征。确定了28篇论文;7例报告了颌下注射,21例报告了四腺注射。没有发现治疗程序或随访时间的重大差异。然而,患者特征报告不佳,结果测量有很大的变化,副作用的评估没有明确描述.结论:这篇综述强调了儿科BoNT-A注射研究中结局指标和患者人群描述符的异质性,限制了在颌下注射和四腺注射之间比较治疗效果的能力。这些发现强调需要更广泛和统一的患者特征报告和实施核心结果测量集,以允许比较研究之间的结果并促进临床实践指南的优化。已知:•关于最初注射BoNT-A治疗小儿流口水的唾液腺没有国际共识。新内容:•基于文献得出最佳初始BoNT-A治疗的结论目前是不可行的。用于量化前流口水的结果指标存在相当大的异质性。通常没有足够的报道和接受腺内BoNT-A治疗的儿童的临床特征。•应制定和实施基于共识的结果测量和患者特征集。
    Paediatric anterior drooling has a major impact on the daily lives of children and caregivers. Intraglandular botulinum neurotoxin type-A (BoNT-A) injections are considered an effective treatment to diminish drooling. However, there is no international consensus on which major salivary glands should be injected to obtain optimal treatment effect while minimizing the risk of side effects. This scoping review aimed to explore the evidence for submandibular BoNT-A injections and concurrent submandibular and parotid (i.e. four-gland) injections, respectively, and assess whether outcomes could be compared across studies to improve decision making regarding the optimal initial BoNT-A treatment approach for paediatric anterior drooling. PubMed, Embase, and Web of Science were searched to identify relevant studies (until October 1, 2023) on submandibular or four-gland BoNT-A injections for the treatment of anterior drooling in children with neurodevelopmental disabilities. Similarities and differences in treatment, patient, outcome, and follow-up characteristics were assessed. Twenty-eight papers were identified; 7 reporting on submandibular injections and 21 on four-gland injections. No major differences in treatment procedures or timing of follow-up were found. However, patient characteristics were poorly reported, there was great variety in outcome measurement, and the assessment of side effects was not clearly described.   Conclusion: This review highlights heterogeneity in outcome measures and patient population descriptors among studies on paediatric BoNT-A injections, limiting the ability to compare treatment effectiveness between submandibular and four-gland injections. These findings emphasize the need for more extensive and uniform reporting of patient characteristics and the implementation of a core outcome measurement set to allow for comparison of results between studies and facilitate the optimization of clinical practice guidelines. What is Known: • There is no international consensus on which salivary glands to initially inject with BoNT-A to treat paediatric drooling. What is New: • Concluding on the optimal initial BoNT-A treatment based on literature is currently infeasible. There is considerable heterogeneity in outcome measures used to quantify anterior drooling.and clinical characteristics of children treated with intraglandular BoNT-A are generally insufficiently reported. • Consensus-based sets of outcome measures and patient characteristics should be developed and implemented.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Review
    背景:患有神经发育障碍的儿童的睡眠问题发生率高于典型人群。关于COVID-19对这种人群睡眠问题的影响知之甚少方法:这项综合评价旨在描述COVID-19大流行(2020-2022年)期间的研究,涉及患有神经发育障碍的儿童和青少年睡眠问题的患病率和管理。全面的数据库搜索被用来识别文章,31项研究被认为适合本综述.
    结果:大多数研究报告在COVID-19限制期间睡眠障碍恶化。所有研究都是在诊所关闭时进行的;只有两项研究涉及音乐疗法和睡眠卫生教育等治疗选择,并发现睡眠问题有所改善。
    结论:未来的研究需要专注于开发干预措施,以远程帮助家庭,并在危机时期为家庭提供准备工具包。
    Sleep issues occur at higher rates in children with neurodevelopmental disorders than in the typical population. Little is known about the impact of COVID-19 on sleep issues in this population METHOD: This integrative review aimed to characterize studies during the COVID-19 pandemic (2020-2022) addressing the prevalence and management of sleep issues in children and youth with neurodevelopmental disorders.Comprehensive database searches were used to identify articles, and 31 studies were considered suitable for this review.
    Most studies reported worsening sleep disturbances during COVID-19 restrictions. All studies were conducted when clinics were closed; only two studies addressed treatment options such as music therapy and sleep hygiene education and found improvement in sleep issues.
    Future research needs to concentrate on developing interventions to assist families remotely and empower families with a toolkit of preparedness in times of crisis.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    背景:家庭全面参与神经发育和智力障碍(NDID)儿童的日常护理。鉴于NDID儿童的普遍流行和日益增加,以及家庭护理对心理的影响,社会,以及对孩子和家庭的经济影响,理解和支持这些家庭是一个重要的公共卫生问题。目标:我们对同伴支持网络进行了范围审查,以了解它们对家庭的影响。考虑到NDID患病率的增加,了解现有网络的含义对于改善和培育未来的支持网络至关重要,这些网络可以补充和减轻现有正式支持系统的负担。设计:对多个数据库进行全面搜索。文章由两名审稿人筛选,任何分歧由第三名审稿人解决。我们探索了关于父母对父母对等支持网络的现有研究,其中包括非正式发展的网络以及涉及团体人际交往过程的正式促进者的网络。研究设计没有限制,文章的日期和设置。我们纳入了所有英文研究,其中包括(i)“对等支持网络”的标识符,“(ii)”神经发育和智力障碍儿童“和(iii)”家庭照顾者的结果。“结果:我们确定了36篇文章。大部分研究是在北美进行的,并且是面对面的网络。其中包括有各种NDID的儿童家庭。从不同的研究中提取的相关信息突出了同行支持网络的特点和发展过程,参加这些网络的家庭护理人员的需求,影响照顾者参与的因素以及同伴支持网络对家庭照顾者的影响。这些网络代表了加强家庭护理人员的一种方式,发展韧性和社会交往。分享相似经历的家庭护理人员互相支持,并相互提供关键信息。虽然结果令人鼓舞,未来的研究需要结合改进的研究设计,以更好地评估同伴支持网络的有效性.此外,在儿童得到支持的同时,同伴支持网络有机发展的研究是有必要的。结论:尽管获得的结果令人鼓舞,我们的研究结果支持需要对同伴支持网络进行进一步的研究研究,并提供更好的设计和对开发中涉及的因素的更详细的描述。
    Background: Families are integrally involved in day-to-day caregiving of children with neurodevelopmental and intellectual disabilities (NDID). Given the widespread and increasing prevalence of children with NDID and the impact of family caregiving on psychological, social, and economic implications for both the child and family, understanding and supporting these families is an important public health concern. Objective: We conducted a scoping review on peer support networks to understand their implications on families. Considering increasing prevalence of NDID\'s, understanding the implications of existing networks is critical to improve and nurture future support networks that can complement and reduce the burden on existing formal support systems. Design: A comprehensive search of multiple databases was conducted. Articles were screened by two reviewers and any disagreements were resolved by a third reviewer. We explored existing research on parent-to-parent peer support networks, which included networks that developed informally as well as those that involved a formal facilitator for the group interpersonal processes. There were no limits on the study design, date and setting of the articles. We included all research studies in English that included an identifier for (i) \"peer support networks,\" (ii) \"children with neurodevelopmental and intellectual disabilities\" and (iii) \"family caregiver outcomes.\" Results: We identified 36 articles. Majority of the studies were conducted in North America, and were face to face networks. They included families of children with a wide range of NDIDs. Relevant information extracted from different studies highlighted peer support network characteristics and development process, needs of family caregivers attending these networks, factors affecting caregiver participation and the impact of peer support networks on family caregivers. These networks represent a way to strengthen family caregivers, developing resilience and social interactions. Family caregivers sharing similar experiences support one another and provide critical information to each other. Although results are encouraging, future studies incorporating improved study designs are needed to better evaluate the effectiveness of peer support networks. Furthermore, studies where peer support networks develop organically while the child is supported are warranted. Conclusion: Although results obtained are encouraging, our findings support the need for further research studies of peer support networks with better designs and more detailed description of the factors involved in the development.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

公众号