Needle biopsy

针吸活检
  • 文章类型: Case Reports
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  • 文章类型: Case Reports
    背景:卵泡树突状细胞肉瘤(FDCS)于1986年首次发现;该疾病的特异性是其稀有性,发病率仅为0.4%,许多医生对它缺乏了解,影像诊断的准确性不高,这很容易延误治疗。本文总结了FDCS的几种特征性影像学表现,为影像医师提供对这种罕见疾病的影像学特性的认识。面对复杂的案件,放射科医师可以考虑这种疾病,并将其纳入鉴别诊断。FDCS主要发生在淋巴结,主要在头部和颈部。主要症状是疲劳,局部疼痛,或无痛肿块。治疗方法不统一,但是学者们一致认为,我们应该尽可能地争取手术的机会。
    方法:本文报告1例术后3年盆腔复发的FDCS。病人在当地医院经术后病理怀疑为淋巴瘤,建议患者定期复查。最近在左盆腔中再次发现软组织肿块。增强CT检查后,放射科医生对之前的淋巴瘤诊断持怀疑态度.随后,北京大学首钢医院进行了穿刺活检。在咨询其他医院后,病理结果拒绝了淋巴瘤的先前诊断,患者被诊断为FDCS。
    结论:FDCS的影像学表现缺乏绝对特异性,但它也具有成像特性,比如巨大肿块中大面积的坏死,肿块中有粗糙的肿块钙化,增强扫描显示“快进慢出”模式,肿瘤里有血管.FDCS主要发生于淋巴结,易误诊为GIST。炎性成肌细胞瘤,淋巴瘤等。放射科医师应继续收集这种疾病的病例,并将疑似病例纳入临床工作的鉴别诊断中。
    Follicular Dendritic Cell Sarcomas (FDCS)was first found in 1986; the specificity of the disease is its rarity, with an incidence of only 0.4%, numerous doctors for its lack of understanding, the accuracy of imaging diagnosis is not great, which is easy to delay the treatment. This article summarizes several characteristic imaging manifestations of FDCS to provide imaging physicians with an understanding of the imaging properties of this rare disease. When faced with complex cases, the radiologist can consider this disease and include it in the differential diagnosis. FDCS occurs mainly in lymph nodes, mainly in the head and neck. The main symptoms are fatigue, local pain, or painless mass. The treatment method is not uniform, but scholars agree that we should strive for the opportunity of surgery as much as possible.
    This paper reported a case of FDCS with pelvic recurrence 3 years after surgery. The patient was suspected to have lymphoma by postoperative pathology in the local hospital, and it is recommended that the patient be reexamined regularly. A soft tissue mass was recently found again in the left pelvic cavity. After an enhanced CT examination, the radiologist was skeptical of the previous diagnosis of lymphoma. Subsequently, a needle biopsy was performed at Peking University Shougang Hospital. The pathological results rejected the prior diagnosis of lymphoma after consultation with additional hospitals, and the patient was diagnosed with FDCS.
    The imaging manifestations of FDCS lack absolute specificity, but it also has imaging characteristics, such as large areas of necrosis in the huge mass, rough mass calcification in the mass, enhanced scan showed \"fast in and slow out\" mode, and there were blood vessels in the tumor. FDCS mainly occurs in lymph nodes and is easily misdiagnosed as GIST, inflammatory myoblastoma, lymphoma, etc. Radiologists should continue to collect cases of this disease and include suspected cases in the differential diagnosis in clinical work.
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  • 文章类型: Journal Article
    我们介绍了一名患有眼眶肿块病变的患者,该病变是头皮骨癌的转移性病变,患者逐渐恶化。一名78岁的男性表现为功能下降,头皮病变迅速增长,持续时间为3个月。除了头皮病变,计算机断层扫描显示偶然发现左外侧眶壁肿瘤。两个病变的细针抽吸显示具有相似形态的恶性细胞。头皮病变的穿刺活检显示出提示腺癌的组织学特征。患者接受了姑息性放疗和免疫疗法,随后死于该疾病。
    We present a patient who presented with an orbital mass lesion which was a metastatic lesion from a porocarcinoma of the scalp with progressive deterioration of the patient.A 78-year-old male presented with functional decline and a rapidly growing scalp lesion of 3 months duration. In addition to the scalp lesion, Computed Tomography showed an incidental finding of a left lateral orbital wall tumour. Fine-needle aspiration of the two lesions revealed malignant cells with similar morphologies. Punch biopsy of the scalp lesion showed histological features suggestive of a porocarcinoma. Patient underwent palliative radiotherapy and immunotherapy and subsequently succumbed to the disease.
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  • 文章类型: Case Reports
    CT-guided percutaneous transthoracic needle biopsy (PTNB) plays a key role in the diagnosis of pulmonary abnormalities. Although the procedure is considered safe and effective, there exists a potential for complications, such as pneumothorax, hemorrhage, hemoptysis, air embolism, and tumor seeding. However, pneumatoceles after CT-guided PTNB have been rarely reported. Herein, we report two cases of pneumatoceles that developed immediately after PTNB for primary lung cancer. A pneumatocele filled with hematoma should be considered in cases with a newly developed nodule along the needle tract during short-term follow-up CT after PTNB.
    컴퓨터단층촬영 유도 경피적 바늘 생검은 폐 이상 진단에 중요한 역할을 하며, 안전하고 효과적이지만 기흉, 출혈, 객혈, 공기 색전증 및 종양 파종과 같은 합병증의 위험이 있다고 알려져 있다. 그러나 시술 후 발생한 기종에 대한 증례 보고는 드물다. 저자들은 원발성 폐암의 경피적 바늘 생검 직후 발생한 기종 2예를 보고하고자 한다. 시술 후 단기 추적검사 컴퓨터단층촬영에서 바늘 경로를 따라 새로 생긴 결절의 경우 혈종으로 찬 기종을 의심해야 한다.
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  • 文章类型: Case Reports
    背景:单核细胞增生李斯特菌(L.单核细胞增多性)是一种机会性兼性厌氧病原体,在自然界中广泛分布。脑感染(脑膜炎和脑膜脑炎)和菌血症是老年人和免疫功能低下个体中李斯特菌病的常见临床表现。由单核细胞增生李斯特菌引起的脑脓肿极为罕见。在这项研究中,我们描述了一个由李斯特菌感染引起的脑脓肿的老年男性病例。
    方法:我们报告一例59岁男性,曾被诊断为急性脑梗死。脓肿穿刺活检和单核细胞增生李斯特菌培养后,诊断发生了变化。患者首先凭经验使用广谱抗生素美罗培南12天(2gQ8h),直到获得培养结果。然后改用口服甲氧苄啶/磺胺甲恶唑160/800mg/12h,持续2周。言语不清的症状,麻木和右腿肌肉力量受损改善。术后2周进行计算机断层扫描(CT)和磁共振成像(MRI)检查,显示脓肿较小,病灶周围水肿减少。患者继续口服甲氧苄啶/磺胺甲恶唑8周。其余右臂功能障碍恢复。六个月后,患者已恢复正常的日常活动,仅表现出右手手指无力。
    结论:有李斯特菌病危险因素的患者应考虑单核细胞增生利斯特菌引起的脑脓肿。病原体感染,包括单核细胞增生李斯特菌,当免疫功能受损的患者出现偏瘫和失语时,应予以考虑。免疫功能正常的患者也应考虑李斯特菌感染。早期根据药敏试验进行穿刺活检或病灶切除,并开始抗生素治疗是治疗此类疾病的关键。
    BACKGROUND: Listeria monocytogenes (L. monocytogenes) is an opportunistic facultative anaerobic pathogen that is widely distributed in nature. Brain infection (meningitis and meningoencephalitis) and bacteremia are common clinical manifestations of listeriosis in elderly and immunocompromised individuals. Brain abscesses caused by L. monocytogenes are extremely rare. In this study, we describe a case of an older male who with a brain abscess caused by Listeria infection.
    METHODS: We report a case of a 59-year-old male who was once diagnosed with acute cerebral infarction. The diagnose was changed after needle biopsy of the abscess and culture of L. monocytogenes. The patient was first empirically used the broad-spectrum antibiotic meropenem for 12 days (2 g Q8 h) until culture results were available, and then switched to oral trimethoprim/sulfamethoxazole 160/800mg/12h for further 2 weeks. The symptoms of slurred speech, numbness and impaired muscle strength of the right leg improved. Computed tomography (CT) and Magnetic resonance imaging (MRI) examination were performed 2 weeks after operation showed smaller abscess and reduced perifocal edema. The patient was continued oral trimethoprim/ sulfamethoxazole for 8 weeks. The remaining right arm dysfunction recovered. After six months, the patient had returned to normal daily activities and only exhibited weakness of the right fingers.
    CONCLUSIONS: Brain abscess caused by L. monocytogenes should be considered in patients who have risk factors for listeriosis. Pathogen infection, including with Listeria monocytogenes, should be taken into account when patients with impaired immune function exhibit hemiplegia and aphasia. Listeria infection should also be considered in immunocompetent patients. Performing needle biopsy or lesion resection and starting antibiotic therapy according to drug susceptibility testing in the early stage is key to treating this kind of disease.
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  • 文章类型: Case Reports
    未经证实:霍奇金淋巴瘤(HL)是一种罕见的血液系统恶性肿瘤,主要发生在年轻人中,而较少发生在老年人中。HL具有来源于B淋巴细胞的特征性细胞(已知的Reed-Sternberg(HRS)细胞)。原发性肝霍奇金病非常罕见,占病例的不到0.4%。由于其罕见的发生,PHL的发病机制尚不清楚,临床表现,实验室发现,和成像特征通常是非特异性的,很难诊断。
    未经授权:69岁沙特女性,已知的高血压病例出现在我们医院,有发热史,黄疸,食欲不振约2周,体重明显下降。
    未经评估:实验室检查结果显示胆汁淤积型,总胆红素107.2mg/dl,碱性磷酸酶2076IU/l,AST153IU/l和ALT73IU/l。超声成像显示肝脏大小正常,弥漫性回声增加,MRCP显示胆囊内有多个结石,没有梗阻或CBD扩张的证据,而泛计算机断层扫描(CT)显示轻度增大和脂肪肝。CT引导下细针穿刺细胞学(FNAC)和肝脏活检与原发性肝霍奇金淋巴瘤一致。
    UNASSIGNED:患者接受了5个周期的ABVD。
    UNASSIGNED:完成5个周期后,患者对治疗表现出良好的反应,肝功能正常化,肝脏CT大小消退。
    未经证实:PHL是一种罕见的疾病。临床表现是可变的,放射学特征不是特异性的。组织学是明确诊断的必要条件。PHL的最佳治疗和结果仍不清楚。ABVD是最经常使用的化疗方案。包括手术和放疗在内的多种方法是另一种选择。
    UNASSIGNED: Hodgkin lymphoma (HL) is an uncommon hematological malignancy that primarily occurs in young adults and less frequently in elderly individuals. HL has characteristics cells derived from B lymphocytes (known Reed-Sternberg (HRS) cells). Primary hepatic Hodgkin disease is very rare presentation accounting for less than 0.4% of the cases. Due to its rare occurrence, the pathogenesis of PHL is still unclear, Clinical manifestations, laboratory findings, and imaging features are usually nonspecific, making it difficult to diagnose.
    UNASSIGNED: 69 years old Saudi Female, known case of Hypertension presented to our hospital with history of fever, jaundice, and poor appetite for about 2 weeks with significant weight loss.
    UNASSIGNED: Laboratory findings showed cholestatic pattern with total bilirubin 107.2 mg/dl, alkaline phosphatase 2076 IU/l, AST 153 IU/l and ALT 73 IU/l. Imaging with US revealed normal liver size with diffuse increase echogenicity, MRCP showed multiple stones within the gallbladder without evidence of obstruction or CBD dilatation and pan-computed tomography (CT) revealed mildly enlarged and fatty liver. CT-guided fine needle aspiration cytology (FNAC) and biopsy from the liver were consistent with primary hepatic Hodgkins lymphoma.
    UNASSIGNED: The patient received 5 cycles of ABVD.
    UNASSIGNED: After the completion of the 5 cycles patient showed good response to the treatment with normalization of her liver function and regression in the size of liver on CT.
    UNASSIGNED: PHL is a rare disease. The clinical presentation is variable and radiological features are not specific. Histology is mandatory for definitive diagnosis. The optimal therapy and outcomes for PHL is still unclear. ABVD is the most frequently used chemotherapy regimen. Multidisplinary approach including surgery and radiotherapy is another option.
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  • 文章类型: Case Reports
    低度子宫内膜间质肉瘤(LGESS)是一种罕见的子宫肿瘤,占所有子宫癌病例的<1%。LGESS有几种变异,表现出平滑肌分化的肿瘤的频率是LGESS病例的10-30%,使这种情况更加罕见。本报告描述了患有平滑肌分化的LGESS患者的病例,经术前穿刺活检诊断为子宫平滑肌瘤,然后接受腹腔镜手术。患者是一名41岁的女性。MRI结果在T2加权图像上显示出弥漫性高强度子宫肿瘤,因此进行了穿刺活检。这个肿瘤最初被诊断为平滑肌瘤,由于活检标本的病理结果,其具有呈梭形排列在脐带中的肿瘤细胞,平滑肌肌动蛋白免疫染色呈阳性。随后对患者进行了随访,29个月后MRI显示肿瘤生长。再次进行穿刺活检,结果与第一次活检相同;因此,该肿瘤被诊断为平滑肌瘤,并进行了腹腔镜子宫切除术。然而,切除子宫的病理结果为小圆形肿瘤细胞和CD10免疫染色阳性,因此肿瘤最终被诊断为LGESS。患者要求随访,手术后20个月无复发迹象。在这种情况下的回顾性检查结果表明,在SMA和CD10的免疫染色分析中仅CD10阳性的区域的存在对于具有平滑肌分化的LGESS的针吸活检诊断很有用。
    Low-grade endometrial stromal sarcoma (LGESS) is a rare uterine tumor, accounting for <1% of all uterine cancer cases. LGESS has several variations and the frequency of tumors exhibiting smooth muscle differentiation is 10-30% of LGESS cases, making such cases even rarer. The present report described the case of a patient with LGESS with smooth muscle differentiation, who was diagnosed as having uterine leiomyoma by preoperative needle biopsy and then underwent laparoscopic surgery. The patient was a 41-year-old woman. MRI findings revealed a diffusely hyperintense uterine tumor on T2-weighted images, thus needle biopsy was performed. This tumor was initially diagnosed as leiomyoma, due to the pathological findings of the biopsied specimen, which possessed tumor cells with spindle-shaped nuclei arranged in a cord and positive immunostaining for smooth muscle actin. The patient was subsequently followed up, and MRI findings after 29 months showed tumor growth. Needle biopsy was performed again and the findings were the same as those of the first biopsy; therefore, this tumor was diagnosed as a leiomyoma and laparoscopic hysterectomy was performed. However, the pathological findings of the excised uterus showed small round tumor cells and CD10 immunostaining positivity, thus the tumor was finally diagnosed as LGESS. The patient requested to be followed up and has shown no signs of recurrence 20 months after surgery. The results of retrospective examination in this case suggested that the presence of regions where only CD10 was positive in immunostaining analysis for SMA and CD10 was useful for needle biopsy diagnosis of LGESS with smooth muscle differentiation.
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  • 文章类型: Case Reports
    医源性脊柱附件神经(SAN)损伤是一种罕见的并发症。它最常见于开放淋巴结活检后。针活检被认为对SAN的风险较低。然而,我们描述了一例66岁的男性患者,他接受了淋巴结肿大的芯针活检,随后出现了同侧肩关节无力和疼痛.体格检查显示肩部凹陷,肩胛骨外侧翼,运动范围减小。随后的研究和磁共振成像显示SAN肌肉完全瘫痪和神经支配。损伤后3个月,通过腓肠神经移植修复了无功能的SAN。患者表现出改善的肩部力量,运动范围,6个月随访时疼痛减轻。SAN损伤的诊断可能具有挑战性,需要及时的手术干预。此病例代表了经腓肠神经移植治疗的芯针活检后SAN完全破坏和麻痹的不寻常病例。我们回顾了医源性SAN损伤的文献,诊断策略,SAN外科修复选项,和结果。SAN损伤的诊断可能具有挑战性,但可以根据SAN损伤的机制和类型提示手术选择。
    Iatrogenic spinal accessory neve (SAN) injury is a rare complication. It most commonly occurs after open lymph node biopsies. Needle biopsy is thought to present lower risk to the SAN. However, we describe a case of a 66-year-old man who underwent core needle biopsy for lymphadenopathy and subsequently experienced ipsilateral shoulder weakness and pain. Physical examination revealed shoulder depression, lateral scapular winging, and decreased range of motion. Subsequent studies and magnetic resonance imaging demonstrated complete paralysis and denervation of SAN muscles. The nonfunctional SAN was repaired by sural nerve grafting 3 months after the injury. The patient demonstrated improved shoulder strength, range of motion, and decreased pain at 6-month follow-up. SAN injuries can be challenging to diagnose and require prompt surgical intervention. This case represents an unusual case of complete SAN disruption and palsy after core needle biopsy treated with sural nerve grafting. We review the literature on iatrogenic SAN injuries, diagnostic strategies, options for SAN surgical repair, and outcomes. SAN injuries can be challenging to diagnose but are amenable to prompt surgical options based on the mechanism and type of SAN injury.
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  • 文章类型: Case Reports
    背景:乳腺癌患者皮肤转移率高。然而,关于治疗乳腺癌皮肤转移的报道很少。
    方法:我们报告一例乳腺癌骨癌的治疗过程,肺,和皮肤转移。该患者是一名43岁的女性,患有晚期乳腺癌和皮肤转移。她通过穿刺活检进行病理诊断以指导治疗。当疾病进展时,通过穿刺活检确定了新的病理诊断,以指导治疗。病人接受了化疗,内分泌治疗,和光动力动力疗法,其次是声动力疗法。
    结论:晚期乳腺癌伴皮肤转移应反复穿刺,以便在疾病进展时获得病理并直接确定诊断。治疗应集中于控制全身转移,而不是当地的疾病。
    BACKGROUND: Breast cancer patients have a high skin metastasis rate. However, reports on treatment of cutaneous metastases of breast cancer are scarce.
    METHODS: We report the treatment process for one breast cancer case with bone, lung, and skin metastases. The patient was a 43-year-old woman with advanced breast cancer and skin metastasis. She underwent pathological diagnosis by needle biopsy to guide the treatment. When the disease progressed, a new pathological diagnosis was determined by needle biopsy to guide the treatment. The patient received chemotherapy, endocrine therapy, and photodynamic dynamic therapy, followed by sonodynamic therapy.
    CONCLUSIONS: Repeated puncture should be performed for advanced breast cancer with skin metastasis, in order to obtain the pathology and directly determine diagnosis when the disease progresses. The treatment should focus on controlling the systemic metastasis, rather than the local disease.
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  • 文章类型: Case Reports
    Cryptococcal granulomatous prostatitis is extremely rare, and there have been few reports of its diagnosis by prostate needle biopsy. The patient, an 81-year-old man, was receiving immunosuppressive treatment for rheumatoid arthritis. He had an oropharyngeal ulcer, and it was diagnosed alongside a methotrexate-related diffuse large B-cell lymphoma. A systemic imaging examination revealed a prostatic tumor-like mass clinically suspected to be prostatic cancer, and a needle biopsy was performed. The biopsy specimen showed various types of inflammatory cell infiltration, and suppurative granuloma and caseous granuloma were observed. Both granulomas showed multiple round and oval organisms that were revealed with Grocott methenamine silver staining. Acid-fast bacilli were not detected by Ziehl-Neelsen staining. We histologically diagnosed granulomatous prostatitis caused by Cryptococcus infection. Caseous granulomas often develop in the prostate after bacillus Calmette-Guerin immunotherapy for bladder cancer, although the possibility of cryptococcal granulomatous prostatitis should also be considered.
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