低场核磁共振(NMR)有三种通用模式:光谱学,成像,和弛豫测量。在过去的12年里,光谱学的模态,也被称为台式核磁共振,紧凑型核磁共振,或者只是低场核磁共振,由于新的永磁材料和设计,已经经历了仪器的发展。因此,台式NMR已成为用于过程分析控制(PAC)的强大分析工具。然而,NMR设备作为分析工具在多个领域的成功应用与它与不同化学计量学方法的耦合有着内在的联系。这篇综述集中在化学分析中的台式NMR和化学计量学的演变,包括在燃料中的应用,食物,制药,生物化学,毒品,代谢组学,和聚合物。该综述还介绍了用于光谱采集的不同低分辨率NMR方法和用于校准的化学计量学技术,分类,歧视,数据融合,校准转移,多块和多路。
Low-field nuclear magnetic resonance (NMR) has three general modalities: spectroscopy, imaging, and relaxometry. In the last twelve years, the modality of spectroscopy, also known as benchtop NMR, compact NMR, or just low-field NMR, has undergone instrumental development due to new permanent magnetic materials and design. As a result, benchtop NMR has emerged as a powerful analytical tool for use in process analytical control (PAC). Nevertheless, the successful application of NMR devices as an analytical tool in several areas is intrinsically linked to its coupling with different chemometric methods. This
review focuses on the evolution of benchtop NMR and chemometrics in chemical analysis, including applications in fuels, foods, pharmaceuticals, biochemicals, drugs, metabolomics, and polymers. The
review also presents different low-resolution NMR methods for spectrum acquisition and chemometric techniques for calibration, classification, discrimination, data fusion, calibration transfer, multi-block and multi-way.