背景:本研究的目的是了解唾液酸酶阳性细菌性阴道病中常见病原体谱的特征和支原体的耐药性。
方法:对2018年8月至2018年10月收集的用于细菌性阴道病(BV)分析的阴道分泌物标本进行了各种技术。这些包括常规白带检查,细菌性阴道病唾液酸酶检测,常见病原体的常规培养,质谱鉴定,和支原体耐药性测试。
结果:共确定了238例BV患者。清洁度等级主要为清洁(+)和清洁(2+),占38.24%和30.67%,分别。阴道分泌物细菌性阴道病检测220例白细胞酯酶阳性,阳性率为92.44%。分析了常规培养的频谱,并将其分为四组:A,B,C,A组为念珠菌阴道炎(13.45%);B组为阴道加德纳菌阴道炎(32.77%);C组为革兰阴性杆菌阴道炎(46.22%);D组为无乳链球菌阴道炎(7.56%)。支原体的鉴定和药敏试验结果表明,BV的检出率较高,阳性率为86.13%。解脲脲原体和人型支原体对四环素类药物有很高的敏感性,但对大环内酯类和喹诺酮类药物有很高的抗性。
结论:细菌性阴道病以各种复杂形式存在,包括念珠菌,阴道加德纳菌,革兰氏阴性杆菌,和无乳链球菌类型。此外,人型支原体的多药耐药呈上升趋势。因此,重视这种情况,并根据病原学特征和常见的抗菌药物敏感性试验做出准确的判断至关重要。这将能够实施有效的治疗干预措施。
BACKGROUND: The objective of this study is to understand the characteristics of the common spectrum of pathogen and the resistance of
Mycoplasma in Sialidase-positive bacterial vaginosis.
METHODS: The vaginal secretion specimens collected from August 2018 to October 2018 for the analysis of bacterial vaginosis (BV) were subjected to various techniques. These included routine leukorrhea examination, bacterial vaginosis sialidase testing, routine culture for common pathogens, mass spectrometry identification, and
Mycoplasma resistance testing.
RESULTS: A total of 238 patients with BV were identified. The cleanliness grading was mostly clean (+) and clean (2+), accounting for 38.24% and 30.67%, respectively. The bacterial vaginosis test for vaginal secretions showed leukocyte esterase positivity in 220 cases, resulting in a positivity rate of 92.44%. The spectrum of routine culture was analyzed and divided into four groups: A, B, C, and D. Group A consisted of Candidal vaginitis (13.45%); group B consisted of Gardnerella vaginalis vaginitis (32.77%); group C consisted of gram-negative bacillus vaginitis (46.22%); and group D consisted of Streptococcus agalactiae vaginitis (7.56%). The identification and antimicrobial susceptibility testing results for
Mycoplasma showed a high detection rate of BV, with a positivity rate of 86.13%. There was a high sensitivity to tetracyclines for Ureaplasma urealyticum and
Mycoplasma hominis, but a high resistance to macrolides and quinolones.
CONCLUSIONS: Bacterial vaginosis existed in various complex forms, including Candida, Gardnerella vaginalis, Gram-negative bacillus, and Streptococcus agalactiae types. Moreover, there was an increasing trend of multi-drug resistance in
Mycoplasma hominis. Therefore, it is crucial to pay attention to this condition and make accurate judgments based on the etiological characteristics and common antimicrobial susceptibility tests. This will enable the implementation of effective therapeutic interventions.