Minimally invasive surgical procedures

微创外科手术
  • 文章类型: Journal Article
    本系统综述和荟萃分析讨论了微创手术技术的效果。特别是ReverdinIsham截骨术,关于中度Hallux外翻患者的功能和放射学结果,常见的足部畸形。该综述包括随机和非随机对照试验,以及病例报告,评估成人中度至重度Hallux外翻的截骨术。直到2023年7月,在MEDLINE和WebofScience等电子数据库中进行了搜索,并使用JoannaBriggs研究所的关键评估工具来评估偏差风险。荟萃分析采用小样本校正的随机效应模型,将结果呈现为标准平均差和平均差以及95%置信区间.包括7项研究,涉及554名患者和643名手术脚,显示AOFAS评分显著改善(从28.61到45.16平均改善36分)和放射学角度的减少,例如手术后的远部跖骨角和外翻角(IMA从-4.68提高-3.07°到-1.46,DMAA从-9.52提高-6.12°到-2.71,HVangle从-17.98提高-15.27°)。尽管取得了这些积极成果,大多数研究都表现出偏见和其他方法学局限性的风险,影响结果的泛化性。总的来说,研究结果强调了ReverdinIsham截骨术在改善中度Hallux外翻患者的功能和放射学参数方面的功效,尽管需要进一步的研究来巩固这些结果。这项研究没有收到具体资金,并且该协议在PROSPERO上注册,编号为CRD-42023445886。
    This systematic review and meta-analysis addresses the effects of minimally invasive surgical techniques, specifically the Reverdin Isham osteotomy, on functional and radiological outcomes in patients with moderate Hallux Valgus, a common foot deformity. The review included randomized and non-randomized controlled trials, as well as case reports, assessing the osteotomy in adults with moderate to severe Hallux Valgus. Searches were conducted in electronic databases such as MEDLINE and Web of Science up until July 2023, and the Joanna Briggs Institute\'s critical appraisal tool was used to assess the risk of bias. Meta-analytical analyses employed a random-effects model with small-sample correction, presenting results as standardized mean differences and mean differences with 95% confidence intervals. Seven studies involving 554 patients and 643 operated feet were included, showing significant improvements in AOFAS scores (an average improvement of 36 points from 28.61 to 45.16) and reductions in radiological angles such as the distal metatarsal angle and hallux valgus angle post-surgery (IMA improved by - 3.07° from - 4.68 to - 1.46, DMAA by - 6.12° from - 9.52 to - 2.71, and HVangle by - 15.27° from - 17.98 to - 12.57). Despite these positive outcomes, most studies exhibited risks of bias and other methodological limitations, impacting the generalizability of the results. Overall, the findings highlight the efficacy of the Reverdin Isham osteotomy in improving both functional and radiological parameters in patients with moderate Hallux Valgus, although further research is warranted to solidify these results. No specific funding was received for this study, and the protocol was registered on PROSPERO with the number CRD-42023445886.
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  • 文章类型: Journal Article
    比较微创和开放式中央胰腺切除术的手术效果。进行了符合PRISMA声明标准的系统评价,以识别和分析比较微创(腹腔镜或机器人)中央胰腺切除术与开放入路的手术结果的研究。使用意图处理数据的随机效应建模,和个体患者作为分析单位,用于分析。包括289名患者的7项比较研究被纳入。两组在基线特征方面具有可比性。微创方法与术中出血量减少相关(平均差异[MD]:-153.13mL,p=0.0004);然而,这并不意味着输血需求减少(比值比[OR]:0.30,p=0.06).微创方法导致术后B-C级胰瘘减少(OR:0.54,p=0.03);通过敏感性分析,这并不一致。两种方法的手术时间没有差异(MD:60.17分钟,p=0.31),Clavien-Dindo≥3种并发症(OR:1.11,p=0.78),术后死亡率(风险差异:-0.00,p=0.81),和住院时间(MD:-3.77天,p=0.08)。微创中央胰腺切除术可能与开放方法一样安全;然而,它是否比开放方法更具优势仍然是辩论的主题。2型错误是一种可能性,因此,需要足够的动力研究才能得出明确的结论;未来的研究可能会使用我们的数据进行动力分析.
    To compare the procedural outcomes of minimally invasive and open central pancreatectomy. A systematic review in compliance with PRISMA statement standards was conducted to identify and analyze studies comparing the procedural outcomes of minimally invasive (laparoscopic or robotic) central pancreatectomy with the open approach. Random effects modeling using intention to treat data, and individual patient as unit of analysis, was used for analyses. Seven comparative studies including 289 patients were included. The two groups were comparable in terms of baseline characteristics. The minimally invasive approach was associated with less intraoperative blood loss (mean difference [MD]: -153.13 mL, p = 0.0004); however, this did not translate into less need for blood transfusion (odds ratio [OR]: 0.30, p = 0.06). The minimally invasive approach resulted in less grade B-C postoperative pancreatic fistula (OR: 0.54, p = 0.03); this did not remain consistent through sensitivity analyses. There was no difference between the two approaches in operative time (MD: 60.17 minutes, p = 0.31), Clavien-Dindo ≥ 3 complications (OR: 1.11, p = 0.78), postoperative mortality (risk difference: -0.00, p = 0.81), and length of stay in hospital (MD: -3.77 days, p = 0.08). Minimally invasive central pancreatectomy may be as safe as the open approach; however, whether it confers advantage over the open approach remains the subject of debate. Type 2 error is a possibility, hence adequately powered studies are required for definite conclusions; future studies may use our data for power analysis.
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  • 文章类型: Journal Article
    目的:孤立性纤维性肿瘤(SFT)是一种少见的良性肿瘤。然而,多达20%的病例显示出局部浸润或转移的恶性趋势。通常出现在胸腔,文献中只有少数病例报道了直肠系膜组织的SFT。完整的手术切除,传统上通过后路,是治疗的选择。这篇综述的目的是证明经肛门微创手术(TAMIS)作为切除良性直肠旁实体瘤的手术方法的安全性和适用性。
    方法:我们报告一例52岁男性患者,该患者偶然诊断为远端直肠系膜SFT。进行TAMIS切除。基于这个案子,我们描述了该程序的步骤和潜在益处,并对文献进行了全面回顾.
    结果:组织病理学证实SFT完全切除。在顺利的术后过程和第四天出院后,多学科委员会建议通过临床检查和MRI进行随访,其中显示愈合良好的瘢痕,在切除后3年内没有复发。
    结论:直肠系膜的SFT是一种非常罕见的实体。据我们所知,这是关于SFT的TAMIS切除术的第一份报告,被证明是完全切除良性直肠旁实体瘤的安全方法。
    OBJECTIVE: Solitary fibrous tumors (SFT) are a rare entity of in majority benign neoplasms. Nevertheless, up to 20% of cases show a malignant tendency with local infiltration or metastasis. Commonly arising in the thoracic cavity, only few cases of SFT of the mesorectal tissue have been reported in the literature. Complete surgical resection, classically by posterior approach, is the treatment of choice. The purpose of this review is to demonstrate the safety and suitability of transanal minimally invasive surgery (TAMIS) as a surgical approach for the resection of benign pararectal solid tumors.
    METHODS: We report the case of a 52-year-old man who was diagnosed incidentally with SFT of the distal mesorectum. Resection by TAMIS was performed. Based on this case, we describe the steps and potential benefits of this procedure and provide a comprehensive review of the literature.
    RESULTS: Histopathology confirms the completely resected SFT. After uneventful postoperative course and discharge on day four, follow-up was recommended by a multidisciplinary board by clinical examination and MRI, which showed a well-healed scar and no recurrence up to 3 years after resection.
    CONCLUSIONS: SFT of the mesorectum is a very rare entity. To our knowledge, this is the first report on a TAMIS resection for SFT, demonstrated as a safe approach for complete resection of benign pararectal solid tumors.
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  • 文章类型: Systematic Review
    目的:自然孔口标本提取(NOSE)是常规经腹取出的替代方法。我们旨在比较微创腹部手术中经阴道标本提取(TVSE)和经腹部标本提取(TASE)的结果。
    方法:PubMed的电子数据库搜索,Embase和CENTRAL从成立到2023年3月进行。包括评估成年女性患者中TVSE与TASE的比较研究。涉及经肛门鼻的研究,腔内手术,或同时行子宫切除术的TVSE被排除.分别估计连续和二分结果的加权平均差(WMD)和比值比。主要结果是术后第1天(POD1)疼痛和住院时间(LOS)。次要结果是手术时间,抢救镇痛,发病率,和宇宙。性的审查,肿瘤学,并完成了技术成果。
    结果:13项研究(2项随机试验,11项回顾性队列研究),涉及1094名患者(TASE583,TVSE511),包括在分析中。七项研究涉及结直肠疾病,六项评估了妇科疾病。TVSE导致POD1疼痛显着降低(WMD1.08,95%CI:0.49,1.68)和较短的LOS(WMD1.18天,95%CI:0.14,2.22),与TASE相比。两组手术时间相似,需要使用TVSE进行术后抢救镇痛的患者较少。总体发病率,以及伤口相关和非伤口相关并发症的发生率在TVSE更好,而吻合口的发病率相当。TVSE的化妆品评分较高。TVSE没有导致较差的性或肿瘤结果。
    结论:与TASE相比,由熟练的腹腔镜操作人员执行TVSE可能是可行和有益的,使用适当的选择标准。继续评估前瞻性研究是必要的。
    OBJECTIVE: Natural orifice specimen extraction (NOSE) is an alternative to conventional transabdominal retrieval. We aimed to compare outcomes following transvaginal specimen extraction (TVSE) and transabdominal specimen extraction (TASE) in minimally invasive abdominal surgery.
    METHODS: An electronic database search of PubMed, Embase and CENTRAL was performed from inception until March 2023. Comparative studies evaluating TVSE versus TASE in adult female patients were included. Studies involving transanal NOSE, endoluminal surgery, or TVSE with concomitant hysterectomy were excluded. Weighted mean differences (WMD) and odds ratio were estimated for continuous and dichotomous outcomes respectively. Primary outcomes were postoperative day 1 (POD1) pain and length of stay (LOS). Secondary outcomes were operative time, rescue analgesia, morbidity, and cosmesis. A review of sexual, oncological, and technical outcomes was performed.
    RESULTS: Thirteen studies (2 randomised trials, 11 retrospective cohort studies), involving 1094 patients (TASE 583, TVSE 511), were included in the analysis. Seven studies involved colorectal disease and six assessed gynaecological conditions. TVSE resulted in significantly decreased POD1 pain (WMD 1.08, 95% CI: 0.49, 1.68) and shorter LOS (WMD 1.18 days, 95% CI: 0.14, 2.22), compared to TASE. Operative time was similar between both groups, with fewer patients requiring postoperative rescue analgesia with TVSE. Overall morbidity rates, as well as both wound-related and non-wound related complication rates were better with TVSE, while anastomotic morbidity rates were comparable. Cosmetic scores were higher with TVSE. TVSE did not result in worse sexual or oncological outcomes.
    CONCLUSIONS: TVSE may be feasible and beneficial compared to TASE when performed by proficient laparoscopic operators, using appropriate selection criteria. Continued evaluation with prospective studies is warranted.
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  • 文章类型: Systematic Review
    背景:经皮穿刺肌腱切开术是一种有前途的方法,可以通过微创干预直接进入肌腱。它们可以快速进行,无需大切口或全身麻醉。然而,报告的程序是不同的,目前在没有指南的情况下进行.
    目的:我们的目的是确定目前文献中描述的经皮穿刺肌腱切开术的适应症。我们的次要目标是确定报告的不同程序,以及它们的功效和安全性。
    方法:遵循PRISMA指南进行了系统评价,以确定提及人类经皮针张力切开术的原始文章,并报告了其应用,描述,有效性或不良事件。不包括非经皮肌腱外科手术和不合格的设计。Downs和Black检查表用于评估偏见的风险。
    结果:共有540项研究来自MEDLINE,Embase,科克伦图书馆,和PEDro数据库。14项临床研究符合纳入标准,并被发现具有可接受的质量(674名个体,1664张力切开术)。我们的结果表明,在儿童和成人中,经皮穿刺性肌腱切开术有多种适应症。我们强调了24条肌腱是上肢和下肢的合格目标。使用16-或18-Ga针进行肌腱切开术,持续1到30分钟,并使用各种程序进行。其疗效主要通过术后触诊时突出显示肌腱不连续性的临床结果进行评估。据报道,上肢和下肢肌腱切开术后的被动活动范围增加,估计并发症发生率为5%。
    结论:这是第一次系统地综合所有关于适应症的现有证据的综述,程序,仅用针进行经皮肌腱切开术的有效性和安全性。目前的证据表明,手术对于治疗各种畸形是安全有效的。
    CRD42022350571。
    BACKGROUND: Percutaneous needle tenotomies constitute a promising approach that enables direct access to tendons through minimally invasive interventions. They can be performed rapidly without need for large incisions or general anaesthesia. However, the reported procedures are heterogeneous and currently conducted without guidelines.
    OBJECTIVE: We aimed to determine the indications for percutaneous needle tenotomies described in the current literature. Our secondary aim was to identify the different procedures reported, as well as their efficacy and their safety.
    METHODS: A systematic review following PRISMA guidelines was conducted to identify original articles that mentioned percutaneous needle tenotomy in humans and reported its application, description, effectiveness or adverse events. Non-percutaneous tendinous surgical procedures and ineligible designs were excluded. The Downs and Black checklist was used to assess the risk of bias.
    RESULTS: A total of 540 studies were identified from the MEDLINE, Embase, Cochrane Library, and PEDro databases. Fourteen clinical studies met the inclusion criteria and were found to have an acceptable quality (674 individuals, 1664 tenotomies). Our results indicated a wide variety of indications for percutaneous needle tenotomies in children and in adults. We highlighted 24 tendons as eligible targets in the upper and lower limbs. Tenotomies were performed with either 16- or 18-Ga needles, lasted from 1 to 30 min, and were performed using various procedures. Their efficacy was mainly assessed through clinical outcomes highlighting tendon discontinuity on palpation after the procedure. Passive range-of-motion gains after tenotomy were reported for both upper and lower limbs with an estimated 5 % complication rate.
    CONCLUSIONS: This is the first review to systematically synthesize all the available evidence on the indications, procedures, efficacy and safety of percutaneous tenotomies exclusively performed with needles. Current evidence suggests that procedures are safe and effective for treating various deformities.
    UNASSIGNED: CRD42022350571.
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  • 文章类型: Journal Article
    当与医疗保健压力相结合时,机器人辅助手术(RAS)的指数增长影响了英国的培训成果,包括能力的学习曲线。目的:确定RAS的当前规定,并调查英国各地在获得最低限度手术(MAS)设施和培训方面的差异。进行了双臂电子调查。第一方对有关机器人实践和未来培训规定的临床线索提出了质疑。第二个调查了受训者和培训师对MAS培训和设施的看法。64%(52/81)的回应信托使用机器人系统。大多数(68%)计划在3年内扩展或购买系统。收集了来自112家英国和爱尔兰共和国医院的171份回复。腹腔镜类别询问受训者是否可以使用正式课程,培训日和sim-boxes。大多数顾问(51.9%)和受训人员(51.6%)报告说,没有正式的机器人手术培训课程。综合反应显示42.1%(n=195/463)表示“是”,39.5%(n=183)“不”和18.4%(n=85)“不知道”。对于组合机器人类别(模拟,培训天数和手术名单)28.3%(n=134/473)回答“是”,51.6%(n=244)说“不”,20.1%(n=95)说“不知道”。这项研究提供了对英国信托机构当前提供的机器人辅助手术的见解,并强调了在正式课程中促进定期临床培训和公平访问MAS模拟的必要性。这可以帮助与机器人实践的扩展并行地调节训练,并且避免显著的技能获取差距和对患者安全的风险。
    When combined with healthcare pressures, the exponential growth of robotic-assisted surgery (RAS) has impacted UK-based training outcomes, including the learning curve to competency. Aim: To ascertain the current provision of RAS and investigate differences in access to minimal access surgical (MAS) facilities and training across the UK. A two-armed electronic survey was conducted. The first arm questioned clinical leads regarding robotic practice and future training provisions. The second investigated trainee and trainers\' perceptions of MAS training and facilities. 64% (52/81) of responding trusts utilise a robotic system. The majority (68% [55/81]) have plans to expand or acquire a system within 3 years. 171 responses from 112 UK and Republic of Ireland hospitals were collected for Arm 2. Laparoscopic categories queried whether trainees had access to a formal curriculum, training days and sim-boxes. Most consultants (51.9%) and trainees (51.6%) reported that there was no formal local training curriculum for robotic surgery. Combined responses demonstrated 42.1% (n = 195/463) said \"yes\", 39.5% (n = 183) \"no\" and 18.4% (n = 85) \"don\'t know\". For combined robotic categories (simulation, training days and operative lists) 28.3% (n = 134/473) responded \"yes\", 51.6% (n = 244) said \"no\" and 20.1% (n = 95) said \"don\'t know\". This study provides insight into the current provision of robotic-assisted surgery at UK trusts and highlights the need to facilitate regular clinical training and equitable access to MAS simulation within a formal curriculum. This may aid regulation of training in parallel with the expansion of robotic practice and avoid a significant skill acquisition gap and risks to patient safety.
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  • 文章类型: Systematic Review
    背景:中央胰腺切除术是一种良性和低度恶性肿瘤的手术方法,位于胰腺的颈部和近端,有利于保存胰腺内分泌和外分泌功能,但发病率高,尤其是术后胰瘘(POPF)。本系统评价和荟萃分析的目的是根据围手术期结果评估微创中央胰腺切除术(MICP)和开放式中央胰腺切除术(OCP)之间的安全性和有效性。
    方法:2003年10月至2023年10月在PubMed上进行了广泛的文献检索,以比较MICP和OCP,Medline,Embase,WebofScience,还有Cochrane图书馆.基于异质性选择固定效应模型或随机效应,并计算了具有95%置信区间(CI)的合并比值比(OR)或平均差(MD)。
    结果:共纳入10项研究,共510名患者。MICP和OCP的POPF差异无统计学意义(OR=0.95;95%CI[0.64,1.43];P=0.82),术中失血量(MD=-125.13;95%CI[-194.77,-55.49];P<0.001)和住院时间(MD=-2.86;95%CI[-5.00,-0.72];P=0.009)与OCP相比,MICP是有利的,MICP的术中输血率明显低于OCP(MD=0.34;95%CI[0.11,1.00];P=0.05)。两组之间的其他结局没有显着差异。
    结论:MICP与OCP一样安全有效,术中出血量少,住院时间短。然而,需要进一步的研究来确认结果。
    BACKGROUND: Central pancreatectomy is a surgical procedure for benign and low-grade malignant tumors which located in the neck and proximal body of the pancreas that facilitates the preservation of pancreatic endocrine and exocrine functions but has a high morbidity rate, especially postoperative pancreatic fistula (POPF). The aim of this systematic review and meta-analysis was to evaluate the safety and effectiveness between minimally invasive central pancreatectomy (MICP) and open central pancreatectomy (OCP) basing on perioperative outcomes.
    METHODS: An extensive literature search to compare MICP and OCP was conducted from October 2003 to October 2023 on PubMed, Medline, Embase, Web of Science, and the Cochrane Library. Fixed-effect models or random effects were selected based on heterogeneity, and pooled odds ratios (ORs) or mean differences (MDs) with 95% confidence intervals (CIs) were calculated.
    RESULTS: A total of 10 studies with a total of 510 patients were included. There was no significant difference in POPF between MICP and OCP (OR = 0.95; 95% CI [0.64, 1.43]; P = 0.82), whereas intraoperative blood loss (MD = - 125.13; 95% CI [- 194.77, -55.49]; P < 0.001) and length of hospital stay (MD = - 2.86; 95% CI [- 5.00, - 0.72]; P = 0.009) were in favor of MICP compared to OCP, and there was a strong trend toward a lower intraoperative transfusion rate in MICP than in OCP (MD = 0.34; 95% CI [0.11, 1.00]; P = 0.05). There was no significant difference in other outcomes between the two groups.
    CONCLUSIONS: MICP was as safe and effective as OCP and had less intraoperative blood loss and a shorter length of hospital stay. However, further studies are needed to confirm the results.
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  • 文章类型: Journal Article
    背景:微创手术,包括腹腔镜和机器人,在全球范围内显着改善了普通外科(GS)实践。虽然非洲大部分地区尚未采用机器人辅助的GS实践,腹腔镜检查已被用于改善手术效果。本研究旨在回顾腹腔镜GS手术(LGSP)进行和评估结果,如转换为开放手术,发病率,和非洲的死亡率。
    方法:四个数据库(PubMed,谷歌学者,WOS,和AJOL)被搜索,识别8022种出版物。筛选后,在非洲进行了40项报告LGSP(n≥2)的研究,结果符合纳入标准。使用R统计软件进行的荟萃分析以95%的转换CI估计了合并的患病率,发病率,和死亡率。
    结果:本研究共分析了在15个非洲国家进行的6381例手术。多数,72.89%,这些程序在塞内加尔进行,南非,和尼日利亚。主要手术为胆囊切除术(37.09%),阑尾切除术(33.36%),和诊断性腹腔镜检查(9.98%)。荟萃分析显示转化率为5%[95%CI:4,7]。附着力(28.13%),出血(16.67%),技术难度(12.50%),设备故障(11.46%)是转换的主要指征。手术部位感染(42.75%)是发病的主要原因。发病率和死亡率分别为7%[95%CI:5,10]和0.12%[95%CI:0,0.29],分别。
    结论:进行了广泛的基础和高级LGSP。获得的结果表明腹腔镜方法的成功实施。重要的是,本研究为非洲微创手术的进一步研究奠定了基础.
    BACKGROUND: Minimally invasive surgery, including laparoscopy and robotics, has significantly improved general surgical (GS) practice globally. While robot-assisted GS practice is yet to be adopted in the majority of Africa, laparoscopy has been utilized to improve surgical outcomes. This study aims to review the laparoscopic GS procedures (LGSPs) performed and evaluate outcomes such as conversion to open surgery, morbidity, and mortality in Africa.
    METHODS: Four databases (PubMed, Google Scholar, WoS, and AJOL) were searched, identifying 8022 publications. Following screening, 40 studies across Africa that reported LGSPs (n ≥ 2) performed and outcomes met the inclusion criteria. A meta-analysis conducted using R statistical software estimated the pooled prevalences with the 95% CI of conversion, morbidity, and mortality.
    RESULTS: A total of 6381 procedures performed in 15 African countries were analyzed in this study. Majority, 72.89%, of the procedures were performed in Senegal, South Africa, and Nigeria. The major procedures performed were cholecystectomy (37.09%), appendicectomy (33.36%), and diagnostic laparoscopy (9.98%). The meta-analysis revealed a conversion rate of 5% [95% CI: 4, 7]. Adhesion (28.13%), hemorrhage (16.67%), technical difficultly (12.50%), and equipment failure (11.46%) were the predominant indications for conversion. Surgical site infection (42.75%) was the major cause of morbidity. The prevalences of morbidity and mortality were 7% [95% CI: 5, 10] and 0.12% [95% CI: 0, 0.29], respectively.
    CONCLUSIONS: A wide range of basic and advanced LGSPs were performed. The outcomes obtained indicate successful implementation of the laparoscopic approach. Importantly, this study serves as a foundational work for further research on minimally invasive surgery in Africa.
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  • 文章类型: Journal Article
    背景:经导管主动脉瓣置换术(TAVR)是高度危重的主动脉瓣狭窄(AS)患者的首选治疗方法,这是一个困难而复杂的过程,给患者和国民健康保险留下了沉重的经济负担。极简TAVR可以简化一部分操作程序,但手术疗效和安全性仍在争论中。
    目的:探讨极简TAVR治疗主动脉瓣狭窄患者的有效性和安全性。
    方法:对PubMed的系统搜索,WebofScience,和Embase数据库进行了涉及在严重主动脉瓣狭窄患者中应用极简TAVR的研究,两名研究人员独立筛选了文献,提取数据,采用STATA16.0软件进行Meta分析。
    结果:九项研究,共涉及3148名AS患者,包括在内。与标准化TAVR相比,极简主义TAVR具有相似的手术成功率,术中透视时间,造影剂的剂量,总手术时间优于标准TAVR。关于手术并发症,两种TAVR的永久性起搏器置入和中度至重度瓣周漏发生率相似,在极简TAVR中,主要血管并发症和主要出血事件的风险显著低于标准TAVR.整体死亡的风险,中风,两种手术在30天内与心血管相关的再入院相似.
    结论:重度主动脉瓣狭窄患者接受极简TAVR治疗的短期疗效和30天临床结局与标准TAVR相似,而最低限度的TAVR可以降低主要血管并发症和出血并发症的风险。
    BACKGROUND: Transcatheter aortic valve replacement (TAVR) is a preferred treatment for patients with highly critical aortic stenosis (AS), which is a difficult and complicated procedure, leaving a heavy economical burden on patients and national health insurance. Minimalist TAVR can simplify a part of the operation procedures, but the surgical efficacy and safety are still under debated.
    OBJECTIVE: Explore the effectiveness and safety of minimalist TAVR in the treatment of patients with aortic stenosis.
    METHODS: A systematic search of PubMed, Web of Science, and Embase databases was conducted for studies involving application of minimalist TAVR in patients with severe aortic stenosis, two researchers independently screened the literature, extracted data and Meta-analysis was performed using STATA 16.0 software.
    RESULTS: Nine studies, involving a total of 3,148 AS patients, were included. Minimalist TAVR has similar surgical success rates compared to standardized TAVR, intraoperative fluoroscopy time, dosage of contrast agent, and total operative time were superior to standard TAVR. Regarding surgical complications, the incidence of permanent pacemaker placement and moderate to severe paravalvular leakage were similar for both TAVR, the risk of major vascular complications and major bleeding events in the minimalist TAVR was significantly lower than the standard TAVR. The risk of overall death, stroke, and cardiovascular-related readmission within 30 days was similar in both procedures.
    CONCLUSIONS: Patients with severe aortic stenosis treated with minimalist TAVR have similar short-term efficacy as well as 30-day clinical outcomes to standard TAVR, while minimalist TAVR could reduce the risk of major vascular complications and bleeding complications.
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  • 文章类型: Journal Article
    腰椎管狭窄(LCS)是影响老年人的常见脊柱疾病。主要是无症状,直到出现神经源性跛行。微创手术(MIS)技术用于治疗腰椎管狭窄(LSS)患者,而具有替代多级减压的管状系统专门用于那些背部疼痛最小且动态成像无机械不稳定性的患者。该研究的目的是评估中东人群激流回旋手术的手术效果和并发症。2015年至2021年之间,有105例腰椎管狭窄症患者(男性61例,女性44例)接受了手术治疗,这些患者在指数手术后六个月使用术前和术后COMI评分(核心结果指标)进行了定期随访。COMI评分从术后平均7分逐步改善至术后6个月的平均3分。术后并发症为硬膜撕裂(6.67%),术后感染(3.81%),机械不稳定性(1.9%),术后神经炎(8.57%)和死亡(1.9%)。
    Lumbar canal stenosis (LCS) is a common spinal disease affecting the elderly. Primarily it is asymptomatic until there is neurogenic claudication. Minimally invasive surgical (MIS) techniques are used to treat patients with lumbar spinal stenosis (LSS), while tubular system with alternative multilevel decompression is specifically used for those with minimal back pain and no mechanical instability on dynamic imaging. The aim of the study is to evaluate surgical outcome of Slalom procedure and complications in Middle East population. One hundred and five patients with lumbar stenosis (61 males and 44 females) underwent the procedure between 2015-2021 who were regularly followed-up using preoperative and postoperative COMI score (the core outcome measure index) at six months after index surgery. Progressive improvement in COMI score from average seven pre-op score to an average of three after six months of index surgery. The postoperative complications were dural tear (6.67%), Postoperative infection (3.81%), mechanical instability (1.9%), postoperative neuritis (8.57%) and death (1.9%).
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