Mesentery

肠系膜
  • 文章类型: Case Reports
    在这份报告中,我们介绍了一名亚裔男性患者,30岁,因胰腺炎入院.在做CT扫描时,在病人的腹部意外发现了一个孤立的肿块。病人的腹痛,是由胰腺炎引起的,在接受手术切除肿块之前已经解决了。随后,患者根据病理诊断为Castleman病。发生在肠系膜的Castleman病非常罕见。因此,我们回顾了有关Castleman病的基本信息,发现关键部分在于诊断和考虑基于不同类型的不同治疗策略.
    In this report, we present an Asian male patient who was 30 years old and admitted to the hospital due to pancreatitis. While undergoing a CT scan, an isolated mass was unexpectedly discovered in the patient\'s abdomen. The patient\'s abdominal pain, which was caused by pancreatitis, had resolved before he underwent surgical resection to remove the mass. Subsequently, the patient was diagnosed with Castleman disease based on pathology. Castleman disease occurring in the mesentery is exceptionally rare. Therefore, we have reviewed the essential information regarding Castleman disease and have found that the crucial part lies in the diagnosis and the consideration of distinct treatment strategies based on different types.
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  • 文章类型: Journal Article
    了解腹部疾病扩散的关键是将腹膜与腹膜外分离。这些区域具有独特的解剖结构,具有明确的单独路径。腹膜由连接的凹陷组成,这些凹陷是潜在的空间,通常不成像,除非含有过量的液体或空气。腹膜凹陷由相对的腹膜表面形成,并通过韧带和肠系膜与顶叶腹膜的连接而细分。疾病通过腹部压力的变化在凹槽内流动。这形成了独特的传播模式。传统上,腹膜外由肾筋膜分层进入肾旁前后间隙和肾周间隙。筋膜包含并引导从所包含的器官与隔室扩散。每个空间都有一个由包含筋膜定义的独特扩散模式。腹膜外连接到形成腹膜下间隙的肠系膜和韧带。这个空间将腹膜外与肠系膜连接起来,允许正常的血管连续体,淋巴管,和神经,但也形成了疾病双向传播的途径。
    Essential to understanding disease spread in abdomen is to separate the peritoneum from the extraperitoneum. These areas have distinct anatomy with well-define separate pathways. The peritoneum is comprised of connected recesses that are potential spaces, normally not imaged except when containing excess fluid or air. Peritoneal recesses are formed by the opposing peritoneal surfaces and subdivided by the attachments of the ligaments and mesenteries to the parietal peritoneum. Disease flows within the recesses by changes in abdominal pressure. This forms a distinct spread pattern. The extraperitoneum is traditionally stratified by the renal fascia into the anterior and posterior pararenal spaces and the perirenal space. The fascia contains and directs spread from the contained organs with the compartments. Each space has a unique spread pattern defined by the containing fascia. The extraperitoneum is connected to the mesenteries and ligaments forming the subperitoneal space. This space interconnects the extraperitoneum with the mesenteries allowing for the normal continuum of blood vessels, lymphatics, and nerves but also forms the pathways for bidirectional spread of disease.
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  • 文章类型: Case Reports
    纤维瘤(DT)是一种罕见的局部侵袭性但非转移性间充质软组织肿瘤,主要发生在腹壁,腹腔,和四肢。它在肠系膜的发生相对罕见。
    本文报道了胃肠外科治疗的两例硬纤维瘤,潍坊市人民医院.第一个病例是一名59岁的男性患者,他之前曾接受过食管胃结合部癌的手术。术后,他的腹内肿块在三个月内迅速增大。第二例是一名60岁的男性患者,偶然发现左下腹部有肿块。两名患者都接受了手术治疗,术后病理诊断为肠系膜纤维瘤。
    硬纤维瘤的治疗仍然具有挑战性。简单的手术切除通常会产生不令人满意的结果,辅助放疗和化疗的疗效也有限。进一步的研究和临床实践是必要的,以改善诊断和治疗策略,旨在提高患者的生存和生活质量。
    UNASSIGNED: Desmoid tumor (DT) is a rare locally aggressive but non-metastatic mesenchymal soft tissue neoplasm that predominantly occurs in the abdominal wall, abdominal cavity, and extremities. Its occurrence in the mesentery is relatively uncommon.
    UNASSIGNED: This article reports two cases of desmoid tumor treated at the Department of Gastrointestinal Surgery, Weifang People\'s Hospital. The first case was a 59-year-old male patient who had previously undergone surgery for esophagogastric junction cancer. Postoperatively, he developed an intra-abdominal mass that rapidly increased in size within three months. The second case was a 60-year-old male patient who incidentally discovered a mass in the left lower abdomen. Both patients underwent surgical treatment, and the postoperative pathological diagnosis was mesenteric desmoid tumor.
    UNASSIGNED: The treatment of desmoid tumor remains challenging. Simple surgical resection often yields unsatisfactory outcomes, and the efficacy of adjuvant radiotherapy and chemotherapy is also limited. Further research and clinical practice are necessary to improve diagnostic and therapeutic strategies, aiming to enhance patient survival and quality of life.
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  • 文章类型: Systematic Review
    小肠神经内分泌肿瘤(SI-NET)是最常见的小肠肿瘤。这些肿瘤的一个特别具有挑战性的子集是那些涉及肠系膜上动脉或静脉的肿瘤,手术的作用和可行性经常受到质疑。本系统综述旨在确定和评估用于这些复杂SI-NET的管理策略。确定的研究显示手术和多模式治疗的积极结果。
    Small intestinal neuroendocrine tumours (SI-NETs) are the most common small intestinal tumours. A particularly challenging subset of these tumours is those that involve the superior mesenteric artery or vein for which the role and feasibility of surgery are often questioned. This systematic review aimed to identify and evaluate the management strategies used for these complex SI-NETs. The identified studies showed positive outcomes with surgery and multimodality therapy.
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    文章类型: Journal Article
    肠系膜脂膜炎(MP)是一种良性疾病,其特征是主要是小肠系膜的脂肪组织的慢性炎症和纤维化。MP通常在腹部的横断面成像上偶然发现,并且在将近一半的患者中可以无症状。据报道,最常见的临床症状是腹痛,其次是腹胀/扩张,腹泻,便秘,呕吐,厌食症,减肥,发烧,萎靡不振,和恶心。在计算机断层扫描中,MP被视为小肠系膜内脂肪衰减增加的团块样区域,通常位于腹部的左上腹。该块状区域包裹肠系膜血管并移位相邻的肠段。淋巴结常见于肠系膜异常区域。MP最常见的鉴别诊断之一是淋巴瘤,和正电子发射断层扫描/计算机断层扫描,如果怀疑并发潜在的恶性肿瘤,可以进行。由于MP的良性性质,治疗决策应以症状的严重程度和并发症的存在为指导.一线药物治疗是泼尼松和他莫昔芬。手术保留用于复发性肠梗阻的病例。本文提供了MP的评论,包括它的流行病学,病理生理学,临床表现,影像学发现,和治疗。
    Mesenteric panniculitis (MP) is a benign condition characterized by chronic inflammation and fibrosis of adipose tissue mainly of the small bowel mesentery. MP is commonly detected incidentally on cross-sectional imaging of the abdomen and can be asymptomatic in up to nearly half of patients. The most frequent clinical symptom reported is abdominal pain, followed by bloating/distention, diarrhea, constipation, vomiting, anorexia, weight loss, fever, malaise, and nausea. On computed tomography, MP is seen as a mass-like area of increased fat attenuation within the small bowel mesentery, usually located in the left upper quadrant of the abdomen. This mass-like area envelops mesenteric vessels and displaces adjacent bowel segments. Lymph nodes are frequently seen within the area of mesenteric abnormality. One of the most common differential diagnoses of MP is lymphoma, and positron emission tomography/computed tomography may be performed if there is suspicion of a concurrent underlying malignancy. Because of the benign nature of MP, treatment decisions should be guided by severity of symptoms and presence of complications. First-line medical treatment is prednisone and tamoxifen. Surgery is reserved for cases of recurrent bowel obstruction. This article provides a review of MP, including its epidemiology, pathophysiology, clinical presentation, imaging findings, and treatment.
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  • 文章类型: Meta-Analysis
    背景:大约三分之一的急性A型主动脉夹层(ATAAD)患者存在术前灌注不良综合征(MPS)。其中,肠系膜灌注不良是患者短期死亡率增加的最大风险.在选定的患者中,通过首先治疗肠系膜灌注不良,提供分阶段的方法可能是可行的,在重症监护环境中优化患者,然后,随后进行中央主动脉修复。本系统综述的目的是总结队列研究,评估术前干预对肠系膜灌注不良的作用。
    方法:对5个数据库进行电子文献检索,以确定所有相关研究,这些研究提供了在中央主动脉修复术之前接受血管内或开放性肠系膜缺血血运重建的患者短期死亡率的研究。主要结果是全因,短期死亡率。次要结果是延迟修复与延迟修复之间的比较死亡率。主动脉修复优先策略,术后剖腹手术率,肠切除术,延迟主动脉修复后的死亡率。
    结果:搜索策略确定了8项符合纳入条件的研究,共有180例患者在肠系膜MPS的情况下接受了延迟主动脉手术。首先是肠系膜血运重建后的加权短期死亡率,延迟主动脉手术策略为22.5%.与中央修复优先策略相比,该策略的死亡率也显着降低(OR0.07,95%CI0.02-0.27),术后剖腹手术/肠切除术的发生率显着降低(OR0.05,95%CI0.02-0.14)。如果病人存活下来接受中央修复,术后加权短期死亡率较低(2.1%).
    结论:对这一证据的总结显示,血流动力学稳定的肠系膜灌注不良患者的短期死亡率较低,随着术后剖腹手术/肠切除术的减少。在那些幸存下来接受中央修复的患者中,在选定的血流动力学稳定患者组中,短期死亡率仍然很低.需要进一步的具有随机或倾向匹配数据的高质量研究来验证这些结果。
    BACKGROUND: Approximately one third of patients with Acute Type A Aortic Dissection (ATAAD) present with pre-operative malperfusion syndromes (MPS). Of these, mesenteric malperfusion represents the greatest risk to patients with respect to increased short-term mortality. In select patients, it may be feasible to offer a staged approach by treating the mesenteric malperfusion first, optimizing the patient in the intensive care setting and then, following with a central aortic repair. The aim of this systematic review is to summarize cohort studies assessing the role of pre-operative interventions for mesenteric malperfusion.
    METHODS: An electronic literature search of five databases was performed to identify all relevant studies providing studies examining short-term mortality on patients who underwent either endovascular or open revascularisation of mesenteric ischemia prior to central aortic repair. The primary outcome was all-cause, short-term mortality. Secondary outcomes were comparative mortality between a delayed repair vs. aortic repair first strategy, rates of postoperative laparotomy, bowel resection, and mortality following delayed aortic repair.
    RESULTS: The search strategy identified 8 studies qualifying for inclusion, with a total of 180 patients who underwent delayed aortic surgery in the setting of mesenteric MPS. The weighted short-term mortality following a mesenteric revascularisation first, delayed aortic surgery strategy was 22.5%. This strategy was also associated with a significantly lower mortality than a central repair first strategy (OR 0.07, 95% CI 0.02-0.27), and a significantly lower rate of postoperative laparotomy/bowel resection (OR 0.05, 95% CI 0.02-0.14). If patients survive to receive central repair, the weighted short-term mortality postoperatively is low (2.1%).
    CONCLUSIONS: A summary of this evidence reveals a lower short-term mortality in hemodynamically stable patients with mesenteric malperfusion, along with a reduction in postoperative laparotomy/bowel resections. Of those patients who survive to receive central repair, short-term mortality remains very low in the select group of hemodynamically stable patients. Further high-quality studies with randomized or propensity matched data are required to verify these results.
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  • 文章类型: English Abstract
    The successful report of total mesorectal excision (TME)/complete mesocolic excision (CME) has encouraged people to apply this concept beyond colorectal surgery. However, the negative results of the JCOG1001 trial denied the effect of complete resection of the \"mesogastrium\" including the greater omentum on the oncological survival of gastric cancer patients. People even believe that the mesentery is unique in the intestine, because they have a vague understanding of the structure of the mesentery. The discovery of proximal segment of the dorsal mesogastrium (PSDM) proved that the greater omentum is not the mesogastrium, and further revised the structure (definition) of the mesentery and revealed its container characteristics, i.e. the mesentery is an envelope-like structure, which is formed by the primary fascia (and serosa) that enclose the tissue/organ/system and its feeding structures, leading to and suspended on the posterior wall of the body. Breakdown of this structure leads to the simultaneous reduction of surgical and oncological effects of surgery. People quickly realized the universality of this structure and causality which cannot be matched by the existing theories of organ anatomy and vascular anatomy, so a new theory and surgical map- membrane anatomy began to form, which led to radical surgery upgraded from histological en bloc resection to anatomic en bloc resection.
    结直肠外科全直肠系膜切除和完整结肠系膜切除的成功报道,推动了人们将这一理念应用到肠外区域,而JCOG1001试验的阴性结果,否认了基于大网膜切除的“胃系膜”完整切除对胃癌患者术后生存的作用。人们甚至以为系膜为肠道独有,其背后的原因是人们对系膜的结构认识模糊。胃背侧系膜近侧段的发现,证明了大网膜不是胃系膜,进而订正了系膜的结构(定义)和“载体”特征,即系膜是固有筋膜和浆膜,包绕着组织、器官、系统及其供养系统,通向和悬挂于体后壁的信封样结构,并揭示了打破该结构将导致手术的外科学和肿瘤学效果同步降低。据此人们很快意识到,这种结构和因果的普遍性,是已有的器官解剖和血管解剖理论无法解释的。于是,新的解剖理论和手术版图——“膜解剖”开始形成,使长期以来强调的“组织学整块切除”理念上升至解剖学整块切除的维度。.
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  • 文章类型: Meta-Analysis
    内疝是腹腔镜Roux-en-Y胃旁路术(LRGB)引起的令人担忧的并发症,有潜在的小肠坏死和梗阻。Medline的电子数据库搜索,Embase,并进行了Pubmed。所有研究调查肠系膜缺损闭合患者的内疝发生率与分析了LRGB期间未关闭的情况。计算赔率比以评估内部疝发生率的差异。共包括14项研究,共20,553名接受LRGB的患者。内疝发生率(220/12,445(2%)与闭合509/8108(6%)未闭合)和小肠梗阻的再次手术(86/5437(2%)闭合与当缺陷闭合时,300/3132(10%)非闭合)减少。与夹子/U形钉相比,当使用缝合线闭合缺损时没有观察到差异。
    Internal hernias are a worrying complication from laparoscopic Roux-en-Y gastric bypass (LRGB), with potential small bowel necrosis and obstruction. An electronic database search of Medline, Embase, and Pubmed was performed. All studies investigating the internal hernia rates in patients whose mesenteric defects were closed vs. not closed during LRGB were analysed. Odds ratios were calculated to assess the difference in internal hernia rate. A total of 14 studies totalling 20,553 patients undergoing LRGB were included. Internal hernia rate (220/12,445 (2%) closure vs. 509/8108 (6%) non-closure) and re-operation for small bowel obstruction (86/5437 (2%) closed vs. 300/3132 (10%) non-closure) were reduced when defects were closed. There was no difference observed when sutures were used to close the defects compared to clips/staples.
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  • 文章类型: Journal Article
    诊断肠和肠系膜创伤对放射科医师提出了重大挑战。尽管这些伤害相对罕见,当它们发生时,可以立即剖腹手术。延迟诊断和治疗与发病率和死亡率增加有关;因此,及时准确的管理至关重要。此外,采用策略区分需要手术干预的重大损伤和认为可通过非手术治疗管理的轻微损伤非常重要.肠和肠系膜损伤是创伤腹部计算机断层扫描(CT)最常被忽视的损伤,在手术治疗之前,高达40%的确诊手术肠和肠系膜损伤未报告。这种高比例的假阴性术前诊断可能是由于几个因素,包括这些伤害的相对罕见,CT上的细微和非特异性外观,放射科医生对伤害的认识有限。为了提高对肠和肠系膜损伤的认识和诊断,这篇文章概述了最常见的伤害,成像评估,CT表现,诊断珍珠和陷阱。增强诊断成像意识将提高术前诊断率,这将节省时间,钱,和生活。
    Diagnosing bowel and mesenteric trauma poses a significant challenge to radiologists. Although these injuries are relatively rare, immediate laparotomy may be indicated when they occur. Delayed diagnosis and treatment are associated with increased morbidity and mortality; therefore, timely and accurate management is essential. Additionally, employing strategies to differentiate between major injuries requiring surgical intervention and minor injuries considered manageable via non-operative management is important. Bowel and mesenteric injuries are among the most frequently overlooked injuries on trauma abdominal computed tomography (CT), with up to 40% of confirmed surgical bowel and mesenteric injuries not reported prior to operative treatment. This high percentage of falsely negative preoperative diagnoses may be due to several factors, including the relative rarity of these injuries, subtle and non-specific appearances on CT, and limited awareness of the injuries among radiologists. To improve the awareness and diagnosis of bowel and mesenteric injuries, this article provides an overview of the injuries most often encountered, imaging evaluation, CT appearances, and diagnostic pearls and pitfalls. Enhanced diagnostic imaging awareness will improve the preoperative diagnostic yield, which will save time, money, and lives.
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  • 文章类型: Case Reports
    一名原本健康的4个月大女孩因腹部扩张而被送往社区卫生服务中心。在接下来的两个月里,女孩的腹部逐渐膨胀。她的检查值得注意的是腹部扩张,mobile,非触痛的腹部肿块。腹部超声图像和随后获得的CT图像显示,外接囊性和实性肿块。这导致肠系膜畸胎瘤的推定诊断。在剖腹手术中完全切除了肿块。病理学,以及手术发现和影像学检查,导致最终诊断。
    An otherwise healthy 4-month-old girl presented to the community health service center because her abdomen was distended. Over the next 2 months, the girl\'s abdomen gradually became more distended. Her examination was notable for abdominal distention with a large, mobile, non-tender abdominal mass. Abdominal ultrasound images and subsequently obtained CT images showed a large, circumscribed cystic and solid mass. This led to the presumptive diagnosis of teratoma of the mesentery. The mass was completely resected during a laparotomy. The pathology, along with the surgical findings and imaging, led to the final diagnosis.
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