目的:母马繁殖后处理是母马繁殖管理中最常见的做法。催产素,子宫灌洗,和宫内(I/U)抗生素通常用作预防性治疗。这项研究旨在确定在环状阿拉伯母马的自然繁殖过程中采用的六种治疗方案中最有效的预防性治疗方案。
方法:当前的研究是针对被细分为三个年龄类别(n=968)的环状阿拉伯母马进行的:I类(5-10岁,n=380),第二类(11-15年,n=361),和第三类(≥16岁,n=227)。繁殖4小时后,进行了6种预防性处理。根据治疗方案,经治疗的母马(n=483)分为六个治疗组:A(n=80),用I/U抗生素(1克庆大霉素)治疗;B(n=81),I/U灌洗(生理盐水500mL);C(n=83),肌内(I/M)催产素(10IU);D(n=82),I/U抗生素和I/M催产素;E(n=78),I/U灌洗和I/M催产素;和F(n=79),用I/U抗生素和I/M催产素进行I/U灌洗。未处理的母马被分类为对照(n=485)。在交配后30天和60天进行超声检查以监测妊娠母马,和母马被跟踪直到产卵。
结果:妊娠和产胎结果显示,在I类年龄中,单独使用催产素或I/U灌洗的催产素治疗显示最高的妊娠率和产胎率(p<0.01)。在第二类年龄中,灌洗治疗的妊娠率和产胎率最高(p<0.01),然而,在第三类年龄,在催产素和I/U灌洗治疗中监测了良好的妊娠率和产胎率(p<0.01)。
结论:全身I/M催产素治疗在早期年龄组母马(5-10岁)中是理想的治疗方法。然而,无论年龄类别如何,所有母马在繁殖后4小时接受全身I/M催产素和生理盐水(0.9%)I/U灌洗治疗后,均表现出较高的妊娠率和产胎率。
OBJECTIVE: Post-breeding treatment is the most common practice in the reproductive management of mares. Oxytocin, uterine lavage, and intrauterine (I/U) antibiotic are usually used as prophylactic therapy. This
study aimed to determine the most efficient prophylactic treatment regimen among six treatment protocols applied during natural breeding of cyclic Arabian mares.
METHODS: The current
study was conducted on cyclic Arabian mares that were subdivided into three age categories (n=968): Category I (5-10 years, n=380), Category II (11-15 years, n=361), and Category III (≥16 years, n=227). Six prophylactic treatments were applied after 4 h of breeding. According to the treatment regimen, treated mares (n=483) were divided into six treatment groups: A (n=80), treated with I/U antibiotic (1 g gentamicin); B (n=81), I/U lavage (normal saline 500 mL); C (n=83), intramuscular (I/M) oxytocin (10 IU); D (n=82), I/U antibiotic and I/M oxytocin; E (n=78), I/U lavage and I/M oxytocin; and F (n=79), I/U lavage with I/U antibiotic and I/M oxytocin. Non-treated mares were classified as controls (n=485). Ultrasonography was performed to monitor pregnant mares 30 and 60 days after mating, and mares were followed until foaling.
RESULTS: Pregnancy and foaling results reveals that in age Category I, treatment with oxytocin alone or oxytocin with I/U lavage showed the highest pregnancy and foaling rates (p<0.01). In age Category II, the highest pregnancy and foaling rates were observed in lavage treatment (p<0.01), whereas, in age Category III, the good pregnancy and foaling rates were monitored in treatment with oxytocin and I/U lavage (p<0.01).
CONCLUSIONS: Treatment with systemic I/M oxytocin is ideal in early age group mares (5-10 years of age). However, irrespective of the age categories, all mares exhibited high pregnancy and foaling rates after treatment with systemic I/M oxytocin and I/U lavage with normal saline (0.9%) 4 h post-breeding.