Mammogram

乳房 X 线照片
  • 文章类型: Journal Article
    目的:自动计算机辅助乳房X线照片分类系统对于女性患者检测和诊断癌症区域非常重要。在这项工作中,乳房X线照片图像分为三种情况:健康,良性和癌症,使用提出的资源高效卷积神经网络(RECNN架构)。
    方法:提出的乳房X线照片图像分类系统由数据增强(DA)模块和空间变换模块以及带有分割模块的CNN架构组成。使用DA方法来增加乳房X线照片图像计数,并且使用空间Gabor变换作为用于将空间像素变换为空间频率像素的空间变换模块。然后,所提出的RECNN架构用于将乳房X线照片图像分类为健康的,良性和癌症病例。Further,在这项工作中,使用所提出的RECNN架构,癌症乳房X线照片图像被诊断为“早期”或“严重”。
    结果:建议的MCDS获得98.65%的SeDR,对于DDSM数据集上的良性病例乳房X线照片图像,98.93%的SpDR和98.84%的ADR,还获得了98.84%的SeDR,DDSM数据集上良性病例乳房X线照片图像的98.7%SpDR和98.92%ADR。拟议的MCDS获得98.94%的SeDR,对于DDSM数据集上的良性病例乳房X线照片图像,98.86%的SpDR和98.96%的ADR,还获得98.89%的SeDR,对于MIAS数据集上的良性病例乳房X线照片图像,98.88%的SpDR和99.03%的ADR。
    结论:在来自DDSM和MIAS数据集的乳房X线照片图像上测试了该提出的方法,并将实验结果与本文中其他类似的乳房X线照片分类工作进行了比较。基于几种绩效评估措施,实验结果表明,MCDS优于目前用于诊断和检测乳腺X线摄影癌症的最新方法。
    OBJECTIVE: The automatic computer-assisted mammogram classification system is important for women patients to detect and diagnose the cancer regions. In this work, the mammogram images are classified into three cases: healthy, benign and cancer, using the proposed Resource Efficient Convolutional Neural Network (RECNN architecture).
    METHODS: The proposed mammogram image classification system consists of Data Augmentation (DA) module and Spatial transformation module and CNN architecture with a segmentation module. The DA methods are used to increase the mammogram image count and Spatial Gabor Transform is used as the spatial transformation module for transforming the spatial pixels into spatial-frequency pixels. Then, the proposed RECNN architecture is used to perform the classification of mammogram images into healthy, benign and cancer cases. Further, the cancer mammogram images are diagnosed as either \'Early\' or \'Severe\' using the proposed RECNN architecture in this work.
    RESULTS: The proposed MCDS obtains 98.65% SeDR, 98.93% SpDR and 98.84% ADR for benign case mammogram images on DDSM dataset and also obtains 98.84% SeDR, 98.7% SpDR and 98.92% ADR for benign case mammogram images on DDSM dataset. The proposed MCDS obtains 98.94% SeDR, 98.86% SpDR and 98.96% ADR for benign case mammogram images on DDSM dataset and also obtains 98.89% SeDR, 98.88% SpDR and 99.03% ADR for benign case mammogram images on MIAS dataset.
    CONCLUSIONS: This proposed method is tested on the mammogram images from DDSM and MIAS datasets and the experimental results are compared with other similar mammogram classification works in this paper. Based on several performance evaluation measures, the experimental results show that MCDS outperforms the state-of-the-art methods currently used for the diagnosis and detection of mammography cancer.
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  • 文章类型: Journal Article
    已经开发了几种基于图像的诊断方法来检查女性乳腺病变的特征,而通过双峰乳腺检查系统结合触诊成像和超声检查的价值仍然未知。
    在福建省妇幼保健院和福建省妇产科医院就诊的424名患者中进行了一项真实世界研究,并使用了双峰乳腺检查(BBE)系统,该系统结合了触诊成像和超声成像。其中,97名患者接受了额外的超声检查,乳房X线照片,或病理检查。这些患者用于评估BBE在解释乳腺病变特征方面的一致性和有效性,与超声检查结果相比,乳房X线照片,和病理检查。
    BBE系统通过触诊成像检测到1517个病变,超声检查1126个病灶(950个实性病灶和176个囊肿),391个非肿块性病变。其中,404例患者诊断为良性,20例诊断为恶性肿瘤。然而,12、9和4例超声诊断为恶性肿瘤,乳房X线照片和病理检查,分别。与超声的综合结果相比,乳房X线照片和病理学,BBE的灵敏度为55.6%,特异性为90.9%,卡帕系数为0.387(0.110,0.665),表明适度的一致性。
    在临床实践中,BBE可用于具有高特异性的乳腺病变特征的评估。诊断效能与超声的综合结果相当,乳房X线照相术,和病理检查。
    UNASSIGNED: Several image-based diagnostic methods have been developed to examine the features of breast lesions among women, while the value of combining palpation imaging and ultrasound by a bimodal breast examination system is still unknown.
    UNASSIGNED: A real-world study was conducted among 424 patients who visited Fujian Maternal and Child Health Hospital and Fujian Obstetrics and Gynecology Hospital, and used the Bimodal Breast Exam (BBE) systems which combines palpation imaging and ultrasound imaging. Among them, 97 patients had additional ultrasound, mammogram, or pathological examination. These patients were used to evaluate the consistency and efficacy of the BBE in interpreting the features of breast lesions as compared to results of ultrasound, mammogram, and pathological examinations.
    UNASSIGNED: The BBE system detected 1517 lesions with palpation imaging, 1126 lesions with ultrasound examination (950 solid lesions and 176 cysts), and 391 non mass lesions. Among them, 404 patients were diagnosed as benign and 20 were diagnosed as malignant tumor. However, 12, 9 and 4 cases were diagnosed as malignant tumors by ultrasound, mammogram and pathological examination, respectively. Compared with the integrative results of ultrasound, mammogram and pathology, the sensitivity of BBE is 55.6%, and the specificity is 90.9%, with a kappa coefficient of 0.387 (0.110, 0.665), indicating moderate consistency.
    UNASSIGNED: In clinical practice, BBE can be used to evaluate features of breast lesions with a high specificity. The diagnostic efficacy is comparable to the integrative results of ultrasound, mammography, and pathological examination.
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  • 文章类型: Journal Article
    目的:这项定性的描述性研究利用了从参与一项全国性研究(n=60)的15名女性子样本中收集的数据,该研究探索了75岁以上女性的乳腺癌筛查动机和行为。该研究旨在了解为什么生活在农村和偏远地区的妇女尽管不在目标年龄范围内,仍可能继续接受移动乳腺癌筛查。
    方法:设置范围从大型城镇到非常偏远的社区(根据莫纳什改良模型(MMM)分类3-7),在这些社区中可以使用BreastScreenAustralia移动筛查服务。
    方法:本研究利用了来自农村和偏远地区15名75岁以上使用移动筛查服务的女性的访谈数据。
    方法:通过电话或在线平台(Zoom)进行了深入的个人访谈。这些被逐字转录并导入到NVivo软件中,以便进行主题分析以确定关键主题。
    结果:许多农村和偏远地区75岁以上的女性表达了继续乳腺癌筛查的明确意图,尽管不再被邀请这样做。他们认为移动服务具有巨大的价值,并且对此表示高度赞赏,但承认有关正在进行的筛查过程的信息来源有限。
    结论:农村和偏远地区的妇女很少与全科医生(GP)讨论正在进行的乳腺癌筛查。需要更多信息来告知女性持续筛查的风险和益处。没有邀请参加筛查的农村妇女报告说,很难知道何时可以提供这项服务。建议不断通知农村地区75岁以上妇女是否有流动服务。
    OBJECTIVE: This qualitative descriptive study draws on data collected from a sub-sample of 15 women participating in a national study (n = 60) exploring the breast cancer screening motivations and behaviours of women aged ≥75 years. The study aimed to understand why women living in rural and remote areas might continue accessing mobile breast cancer screening despite being outside the targeted age range.
    METHODS: Settings ranged from large towns to very remote communities (according to Monash Modified Model (MMM) classification 3-7) where BreastScreen Australia mobile screening services were available.
    METHODS: Interview data from 15 women aged ≥75 years living in rural and remote locations who had used mobile screening services was utilised for this study.
    METHODS: In-depth individual interviews were conducted via telephone or online platform (Zoom). These were transcribed verbatim and imported into NVivo software to enable thematic analysis to identify key themes.
    RESULTS: Many women aged ≥75 years in rural and remote areas expressed clear intentions to continue breast cancer screening, despite no longer being invited to do so. They perceived great value in the mobile service and were highly appreciative for it yet acknowledged limited sources of information about the process of ongoing screening.
    CONCLUSIONS: Few women in rural and remote areas had discussed ongoing breast cancer screening with their general practitioner (GP). More information is required to inform women about the risks and benefits of ongoing screening. Without an invitation to attend screening rural women reported difficulty in knowing when the service would be available. Ongoing notification of the availability of mobile services for women aged ≥75 years in rural areas is recommended.
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  • 文章类型: Case Reports
    在无症状患者的乳房X线筛查照片上发现了一例广泛的气肿,该患者于2周前因上臂松弛而接受了氦等离子体治疗。
    皮下气肿罕见并发症,在氦等离子体处理之后,已经进行了讨论,以强调这种肺气肿通常是自限性的。
    A case is presented of extensive pneumomastia seen on a screening mammogram of an asymptomatic patient who had helium plasma treatment 2 weeks earlier for flabby upper arms.
    UNASSIGNED: Rare complications of subcutaneous emphysema, following helium plasma treatment, have been discussed to highlight that such emphysema is usually self-limiting.
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  • 文章类型: Journal Article
    背景:结核性乳腺炎(TBM),是一种罕见的肺外结核.结核性乳腺炎与恶性肿瘤和其他肉芽肿性疾病的临床和放射学重叠,连同它的低杆菌性质,让它成为诊断挑战。在我们的研究中,我们的目的是评估一个流行国家的微生物阴性肉芽肿性乳腺炎病例对抗结核治疗(ATT)的放射学反应.
    方法:分析87例乳腺活检显示肉芽肿性病变的患者。其中,我们的研究包括49例接受ATT治疗并至少进行了两次连续超声随访的患者。乳房X线照片和超声用于初始成像。随后,超声用于连续随访.Mantoux皮肤测试,抗酸染色和组织样本的组织学检查是其他使用的研究。
    结果:放射学,在超声波上,在18例患者中注意到界限清楚的低回声肿块,其次是15例带有管状延伸的不明确集合,脓肿8例,局灶性异质性8例。ATT之后,17例患者在4周内表现出放射学分辨率,其中18人在3个月时,6个月内有9个.
    结论:对ATT的出色和迅速的放射学反应,表明需要高度怀疑结核性乳腺炎(TBM),在流行国家,即使微生物测试结果可能是阴性的。
    BACKGROUND: Tuberculous mastitis (TBM), is an uncommon form of extra-pulmonary tuberculosis. Clinical and radiological overlap of tuberculous mastitis with malignancy and other granulomatous conditions, along with its paucibacillary nature, make it a diagnostic challenge. In our study, we aim to assess the radiological response of microbiologically negative granulomatous mastitis cases to anti-tuberculous treatment (ATT) in an endemic country.
    METHODS: Eighty-seven cases demonstrating granulomatous lesions on breast biopsy were identified. Of these, 49 patients who were treated with ATT and had at least two serial ultrasound follow-ups were included in our study. Mammogram and ultrasound were used for initial imaging. Subsequently, ultrasound was used for serial follow-up. Mantoux skin test, acid fast staining and histological examination of tissue sample were the other investigations used.
    RESULTS: Radiologically, on ultrasound, well-circumscribed hypoechoic masses were noted in 18 patients, followed by ill-defined collections with tubular extensions in 15 cases, abscesses in 8, and a focal heterogeneity in 8 patients. Following ATT, 17 patients showed radiological resolution in 4 weeks, 18 of them at 3 months, and nine of them in 6 months.
    CONCLUSIONS: Excellent and prompt radiological response to ATT, indicates the need for a high degree of suspicion for tuberculous mastitis (TBM), in endemic countries, even though microbiological tests may turn out negative.
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  • 文章类型: Journal Article
    分析COVID-19大流行是否对筛查有影响,在帕拉州50岁以下女性乳腺癌的诊断和治疗。
    回顾性,采用定量方法的横断面研究,使用巴西统一卫生系统信息技术部的数据。(数据)。大流行前(2018-2019)和大流行(2020-2021)期间进行的考试数量根据百分比变化进行了分析,对检查时间和治疗开始时间应用卡方检验和G检验。
    在大流行期间,有更多的筛查乳房X线照片(+3.68%),细胞学(+23.68%),组织学(10.7%)和较低的诊断性乳房X线照片(-38.7%)。在大流行期间,进行检查的时间间隔长达30天,用于筛查和诊断检查,超过60天开始治疗。
    尽管结果表明,在大流行期间,乳腺癌的筛查和诊断程序数量有所增加,除了诊断性乳房X线照相术,当考虑概率值时,该研究指出,从统计学上讲,COVID-19大流行并没有干扰乳腺癌的作用,50岁以上的女性,在帕拉州。考虑到护理的自主性及其在公共卫生中的作用,由负责初级保健计划的专业人员在危机时期实施应急计划,以使人口不会得不到帮助。
    UNASSIGNED: To analyze whether the COVID-19 pandemic had an impact on the screening, diagnosis and treatment of breast cancer in women up to 50 years of age in the state of Pará.
    UNASSIGNED: Retrospective, cross-sectional study with a quantitative approach, using data from the Information Technology Department of the Brazilian Unified Health System. (DATASUS). The number of exams carried out in the pre-pandemic (2018-2019) and pandemic (2020-2021) period was analyzed based on the percentage variation, application of the chi-square test and G test for the time of exams and start time of treatment.
    UNASSIGNED: During the pandemic period, there was a greater number of screening mammograms (+3.68%), cytological (+23.68%), histological (+10.7%) and a lower number of diagnostic mammograms (-38.7%). The time interval for carrying out the exams was up to 30 days for screening and diagnostic exams and more than 60 days to start treatment during the pandemic period.
    UNASSIGNED: Although the results indicate an increase in the number of screening and diagnostic procedures for breast cancer during the pandemic period, with the exception of diagnostic mammography, when considering probability values, the study points out that statistically the COVID-19 pandemic did not interfere with actions of breast cancer, in women over 50 years of age, in the state of Pará. Considering the autonomy of nursing and its role in public health, it is up to the professionals who are in charge of primary care programs to implement contingency plans in periods of crisis so that the population is not left unassisted.
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  • 文章类型: Journal Article
    该质量改进项目实施了护士主导的高风险筛查转诊方案,以更早地识别乳腺癌风险增加的女性。乳腺癌风险评估工具用于MA。
    This quality improvement project implemented a nurse-led high-risk screening referral protocol for earlier identification of women at increased risk for breast cancer. The Breast Cancer Risk Assessment Tool was used at the ma.
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  • 文章类型: Journal Article
    由乳腺放射科医师确定并且还通过应用自动估计的乳腺密度已经被广泛研究。然而,尚未有研究阐明乳腺放射科医师使用这些应用是否能提高阅读效能.因此,本研究旨在评估乳腺放射科医师使用应用的有效性.柯尼卡美能达开发的乳腺密度评估应用程序(App),Inc.(东京,日本)被使用。进行独立和顺序测试以评估当前和第二看模式的有用性。使用顺序和独立测试对50和100例进行了评估,分别。每个数据集是基于由制定日本乳腺密度指南的专业乳腺放射科医师的评估来配置的。九位乳腺放射科医生评估了乳腺含量比率和乳腺密度;计算了观察者之间和专家与观察者之间的变异性。还记录完成实验所需的时间。观察者之间的差异与应用程序有关,正如独立测试所揭示的那样。应用程序的使用显着改善了观察者对乳腺含量比率的反应与专家的反应之间的一致性,使观察者评估100个病例所需的平均时间减少了186.9秒。然而,序贯测试的结果并不表明该App的有效性.这些发现表明,应用程序的并发使用提高了阅读效率。
    Breast density determined by breast radiologists and also automatically estimated by applications has been widely investigated. However, no study has yet clarified whether the use of these applications by breast radiologists improves reading efficacy. Therefore, this study aimed to assess the usefulness of applications when used by breast radiologists. A Breast Density Assessment application (App) developed by Konica Minolta, Inc. (Tokyo, Japan) was used. Independent and sequential tests were conducted to assess the usefulness of the concurrent- and second-look modes. Fifty and 100 cases were evaluated using sequential and independent tests, respectively. Each dataset was configured based on the evaluation by an expert breast radiologist who developed the Japanese guidelines for breast density. Nine breast radiologists evaluated the mammary gland content ratio and breast density; the inter-observer and expert-to-observer variability were calculated. The time required to complete the experiments was also recorded. The inter-observer variability was significant with the App, as revealed by the independent test. The use of the App significantly improved the agreement between the responses of the observers for the mammary gland content ratio and those of the expert by 6.6% and led to a reduction of 186.9 seconds in the average time required by the observers to evaluate 100 cases. However, the results of the sequential test did not suggest the effectiveness of the App. These findings suggest that the concurrent use of the App improves reading efficiency.
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  • 文章类型: Case Reports
    Rosai-Dorfman-Destombes(RDD)疾病也被称为伴有大量淋巴结病的窦组织细胞增生症。它是儿童和年轻人罕见的异质性疾病。大多数RDD患者通常表现为无痛性淋巴结病,而结外和多系统表现的疾病是不寻常的。诊断基于影像学与临床病理相关性。Flourine-18氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描对于RDD病变的初始分期很有用,具有类似的外观和亲和力,如中度和高度淋巴瘤。这里,我们介绍了一例55岁女性患者的左乳腺肿块,结果是结外Rosai-Dorfman病.
    Rosai-Dorfman-Destombes (RDD) disease is also known as sinus histiocytosis with massive lymphadenopathy. It is an uncommon heterogeneous disease of children and young adults. Most of the patients with RDD generally present with painless lymphadenopathy, while extranodal and multisystem manifestation of the disease is unusual. The diagnosis is based on the imaging with clinicopathological correlation. Flourine-18 fluorodeoxyglucose positron emission tomography/computed tomography is useful for the initial staging of the RDD lesions, which have similar appearance and avidity like intermediate and high-grade lymphomas. Here, we present the case of a 55-year-old female presented with left breast mass that turned out to be the extranodal Rosai-Dorfman disease.
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  • 文章类型: Journal Article
    乳房X光检查的比较解释变得越来越重要,发展乳房X线照片的减法处理和配准方法至关重要。然而,非刚性图像配准很少应用于仅用软组织构造的受试者,比如乳房X线照片.我们检查了是否可以使用非刚性图像配准来执行用于乳房X线照片比较解释的减法处理。作为一项初步研究,我们通过将非刚性图像配准应用于正常乳房X光检查来评估减法处理的结果,假设左乳和右乳之间的比较解释。中外侧斜视乳房X线照片取自非癌症患者,并分为1000例进行训练,100例用于验证,和500个案例进行测试。应用非刚性图像配准以将水平翻转的左乳房乳房X线照片与右乳房X线照片对齐。我们比较了在应用和不应用非刚性图像配准的情况下,双边图像(DifferenceImage)差异的绝对差异之和(SAD)。统计上,应用非刚性图像配准后的平均SAD显著低于未应用非刚性图像配准的平均SAD(无:0.0692;有:0.0549(p<0.001)).在使用乳房区域的四个亚组中,乳腺密度,压缩乳房厚度,和没有非刚性图像配准的差异图像,在非刚性图像配准的情况下,差异图像的平均SAD也显著低于无刚性图像配准的情况(p<0.001)。发现非刚性图像配准在对齐双侧乳房X线照片中足够有用,预计它将成为开发乳房X线照片比较解释支持系统的重要工具。
    A comparative interpretation of mammograms has become increasingly important, and it is crucial to develop subtraction processing and registration methods for mammograms. However, nonrigid image registration has seldom been applied to subjects constructed with soft tissue only, such as mammograms. We examined whether subtraction processing for the comparative interpretation of mammograms can be performed using nonrigid image registration. As a preliminary study, we evaluated the results of subtraction processing by applying nonrigid image registration to normal mammograms, assuming a comparative interpretation between the left and right breasts. Mediolateral-oblique-view mammograms were taken from noncancer patients and divided into 1000 cases for training, 100 cases for validation, and 500 cases for testing. Nonrigid image registration was applied to align the horizontally flipped left-breast mammogram with the right one. We compared the sum of absolute differences (SAD) of the difference of bilateral images (Difference Image) with and without the application of nonrigid image registration. Statistically, the average SAD was significantly lower with the application of nonrigid image registration than without it (without: 0.0692; with: 0.0549 (p < 0.001)). In four subgroups using the breast area, breast density, compressed breast thickness, and Difference Image without nonrigid image registration, the average SAD of the Difference Image was also significantly lower with nonrigid image registration than without it (p < 0.001). Nonrigid image registration was found to be sufficiently useful in aligning bilateral mammograms, and it is expected to be an important tool in the development of a support system for the comparative interpretation of mammograms.
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