Lymphatic system

淋巴系统
  • 文章类型: Case Reports
    肠系膜囊性淋巴管瘤是一种罕见的良性腹部淋巴管畸形,估计发病率为1/250,000。临床表现范围从无症状肿块到急性腹痛。诊断调查包括超声波,腹部计算机断层扫描,或者磁共振成像.完整的手术切除是推荐的治疗方法。我们介绍一名11岁女性腹部绞痛,有6个月的逐渐膨胀的历史,便秘,和多尿,没有呕吐的发生。临床检查显示,可移动,触诊时无痛性腹部肿块迟钝。超声显示腹部多腔囊性肿块,对比增强的计算机断层扫描显示,一个大的多腔囊性肿块累及大部分腹部。进行了完整的手术切除,镜检证实诊断为肠系膜囊性淋巴管瘤。该病例强调了在儿科患者腹部肿块的鉴别诊断中考虑肠系膜囊性淋巴管瘤的重要性。即使是在更罕见的年龄组。成像有助于诊断和手术计划。完全切除可以抑制感染和复发的风险。
    Mesenteric cystic lymphangiomas are a rare benign abdominal malformation of lymphatic vessels, with an estimated incidence of 1 per 250,000. Clinical presentation ranges from asymptomatic masses to acute abdominal pain. Diagnostic investigation includes ultrasound, abdominal computed tomography, or magnetic resonance imaging. Complete surgical excision is the recommended treatment. We present an 11-year-old female with abdominal cramps, and a 6-month history of gradually developing distension, constipation, and polyuria, without the occurrence of vomiting. Clinical examination revealed a soft, movable, painless abdominal mass with dullness on palpation. Ultrasound showed multi-cavity cystic masses in the abdomen, and a contrast-enhanced computed tomography scan revealed a large multi-cavity cystic mass involving most of the abdomen. A complete surgical excision was performed, and microscopic examination confirmed the diagnosis of mesenteric cystic lymphangioma. This case underscores the importance of considering mesenteric cystic lymphangiomas in the differential diagnosis of abdominal masses in pediatric patients, even in rarer age groups. Imaging aids in diagnosis and surgery planning. Complete excision curbs the risk of infection and recurrences.
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  • 文章类型: Journal Article
    囊性水瘤(CH)也称为淋巴管瘤,是淋巴管的囊性畸形,可以发生在身体的任何地方。它在成年期的发病率被认为是罕见的,它在颈部的发生甚至更罕见,迄今为止只有少数病例报告可用。我们介绍一例成人颈部CH,并对其进行文献综述。一名30岁男性,颈部左侧无痛性肿胀,持续时间2年。调查显示,颈部左下前部有一个囊性肿块,通过手术切除完整的囊。活检报告证实了诊断。当成人颈部遇到囊性病变时,应考虑CH的鉴别诊断。细胞学和放射学评估对于确定其位置和诊断是必要的。尽管有各种保守的管理方式,他们只在某些情况下被雇用,手术切除CH被认为是黄金标准。复发的几率从15%到20%不等。
    Cystic Hygroma (CH) also referred to as lymphangioma, is a cystic malformation of the lymphatic vessels that can occur anywhere in the body. Its incidence in adulthood is considered rare and its occurrence in the neck is even rarer and only a few case reports are available till date. We present a case of adult CH of the neck and the literature review of the same. A 30-year-old male presented with painless swelling in the left side of the neck of 2 years duration. Investigations showed a cystic mass on the left lower anterior part of the neck which was surgically removed in-toto with the intact capsule. The biopsy report confirmed the diagnosis. A differential diagnosis of CH should be considered when a cystic lesion is encountered in the neck of an adult, cytological and radiological evaluation is necessary for defining its location and diagnosis. Although various conservative modalities of management are available, they are employed only in certain situations, and surgical excision of CH is considered the gold standard. The chances of recurrence range from 15 to 20%.
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  • 文章类型: Case Reports
    囊性水瘤是一种良性的先天性淋巴管畸形,发病率为6000名活产儿中的1名。大多数病例与遗传综合征有关,并可能损害胎儿的生存能力。由于它的稀有性,综合数据有限,主要依靠病例报告。
    方法:一名21岁的孕妇,在妊娠27周时出现腹痛分诊。腹部超声检查显示,一个活的女性胎儿,估计胎儿体重为734g,复杂的囊性肿块导致颈部过度延伸。鉴于预后不良,终止妊娠。肿块的组织病理学证实其为囊性水瘤。
    在有限资源设置中,由于缺乏足够的资源对出生后的母亲和婴儿进行复杂的跨学科干预,因此对巨大的囊性水瘤的管理通常需要终止妊娠。在这种情况下,重点应该转向促进共同决策和敏感的患者咨询。
    结论:产前诊断的囊性湿度瘤通常比出生后诊断的预后较差。囊肿的管理,特别是那些产前诊断的,在资源不足的设置中表示持续的挑战。咨询和治疗建议必须根据肿瘤特征进行调整,预期预后,以及在给定的临床环境中进行医疗或手术干预的可行性。
    UNASSIGNED: Cystic hygroma is a benign congenital malformation of lymphatic and blood vessels, with an incidence of 1 in 6000 live births. Most cases are associated with genetic syndromes and can compromise fetal viability. Due to its rarity, comprehensive data is limited, mainly relying on case reports.
    METHODS: A 21-year-old pregnant woman at 27 weeks\' gestation presented to triage with abdominal pain. Abdominal ultrasound revealed a single living female fetus with an estimated fetal weight of 734 g and a complex cystic mass causing hyper-extension of the neck. The pregnancy was terminated given the poor prognosis. Histopathology of the mass confirmed it to be a cystic hygroma.
    UNASSIGNED: In limited-resource settings, management of huge cystic hygromas often necessitates termination of pregnancy due to a lack of sufficient resources for complex interdisciplinary interventions for the mother and infant after birth. In such cases, focus should be shifted toward promoting shared decision-making and sensitive patient counseling.
    CONCLUSIONS: Cystic hygromas that are diagnosed prenatally generally have a poorer prognosis than those diagnosed after birth. The management of cystic hygramas, particularly those diagnosed prenatally, represents a persistent challenge in low-resourced settings. Counseling and treatment recommendations must be tailored based on tumor characteristics, the expected prognosis, and the feasibility of medical or surgical intervention in a given clinical environment.
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  • 文章类型: Journal Article
    疣状象鼻病(ENV)是慢性淋巴水肿的罕见并发症,导致进行性皮肤肥大和下肢毁容。我们介绍了一个79岁的ENV患者的不寻常病例,谁有丹毒发作治疗和抗生素治愈。患者几年前出现下肢进行性无痛性淋巴水肿,复杂的皮肤变化。生物学和放射学测试不客观的任何原因。对患者提出了压迫治疗。ENV的特征是淋巴水肿和皮肤异常。ENV的管理通常具有挑战性,但是已经报道了各种成功的医学和外科治疗策略。
    Elephantiasis nostras verrucosa (ENV) is a rare complication of chronic lymphedema, leading to progressive cutaneous hypertrophy and disfigured lower extremities. We present an unusual case of a 79-year-old man with ENV, who had an episode of erysipelas treated and cured with antibiotics. The patient presented with progressive painless lymphedema of the lower limb years ago, complicated with skin changes. The biology and radiology test does not objective any causes. The compression therapy was proposed to the patient. ENV is characterized by lymphedema and skin anomaly. Management of ENV is often challenging, but a variety of successful medical and surgical treatment strategies have been reported.
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  • 文章类型: Case Reports
    背景:外生殖器淋巴水肿是一种罕见的疾病,其特征是阴囊皮肤和皮下组织肿胀,由于淋巴引流的病理学。随着时间的推移,纤维化的发展导致患者生活质量的严重损害。虽然保守管理通常是第一线的方法,手术病例可能需要手术干预,以实现全面和持久的改善。
    方法:我们介绍了一例43岁的肥胖男性患者,他主诉持续的双侧阴囊肿胀达三个月。临床检查显示压力惰性,软,两侧阴囊大量肿胀。超声检查结果证实了弥漫性水肿性阴囊壁增厚。建议患者开始物理治疗并坚持保守治疗。由于质量的衰弱大小,患者选择切除阴囊肿胀,然后进行阴囊成形术。
    本案例报告探讨了演示文稿,症状和体征,对患者生活的影响,和阴囊淋巴水肿的各种管理选择。它强调了诊断和治疗决策过程中涉及的复杂性,强调需要一种量身定制的多学科方法。
    结论:首先必须排除危及生命的阴囊淋巴水肿的原因,以确保最佳的患者护理。在整体管理策略中应仔细考虑手术干预措施的整合,以获得最佳和全面的结果。阴囊成形术,在阴囊淋巴水肿的背景下,不仅提高了生活质量,而且对性功能也有积极影响。
    人际交往和沟通技巧,医学知识,病人护理,基于实践的学习和改进。
    BACKGROUND: Lymphedema of the external genitalia is a rare condition characterized by swelling of the scrotal skin and subcutaneous tissue, resulting from a pathology in lymphatic drainage. Over time, the development of fibrosis leads to a considerable impairment in the patient\'s quality of life. While conservative management is generally the first-line approach, surgical cases may necessitate surgical intervention to achieve comprehensive and lasting improvements.
    METHODS: We present the case of a 43-year-old obese male patient who presented to the clinic with a complaint of persistent bilateral scrotal swelling for three months. Clinical examination revealed a pressure-indolent, soft, and massively enlarged swelling of the scrotum on both sides. Ultrasound findings confirmed a diffusely thickened edematous scrotal wall. The patient was advised to start physiotherapy and adhere to conservative management. Due to the debilitating size of the mass, the patient opted for excision of the scrotal swelling followed by scrotoplasty.
    UNASSIGNED: This case report explores the presentation, signs and symptoms, impact on patients\' lives, and various management options for scrotal lymphedema. It underscores the intricacies involved in the diagnosis and treatment decision-making process, emphasizing the need for a tailored and multidisciplinary approach.
    CONCLUSIONS: It is imperative to initially rule out life-threatening causes of scrotal lymphedema to ensure optimal patient care. The integration of surgical interventions should be carefully considered in the overall management strategy for optimal and comprehensive results. Scrotoplasty, in the context of scrotal lymphedema, not only improves the quality of life but also positively influences sexual function.
    UNASSIGNED: Interpersonal and communication skills, Medical knowledge, Patient care, Practice-based learning and improvement.
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  • 文章类型: Case Reports
    乳糜腹水是一种罕见的腹水形式,其特征是富含甘油三酯的乳状液。它与淋巴引流不良有关。我们报告一例乳糜腹水,显示滤泡性淋巴瘤。
    方法:一名73岁的男子,有6个月的腹胀病史,原因是乳糜腹膜炎。胸腹盆腔CT扫描显示大量腹膜内和腹膜后肿块与十二指肠胰腺块分不开,并包围肠系膜血管,下腔静脉和肾血管;腹水丰富,纵隔多发,子宫肠衣,腹膜后,髂和腹股沟腺巨突。通过腹膜后肿块的放射引导活检保留了滤泡性淋巴瘤的诊断。患者每周进行穿刺和免疫化疗。路线不利,两个周期的免疫化疗后,其特征是腹水感染。我们的患者出现严重脓毒症并死亡。
    乳糜腹水合并滤泡性淋巴瘤是一种特殊表现。病理生理机制是由外部压力引起的膈下淋巴引流的障碍,导致扩张的浆膜下淋巴管漏入腹膜腔。组织学确认是治疗淋巴瘤引起的乳糜腹水的基础。
    结论:乳糜腹水显示淋巴瘤是一种独特的疾病。管理的关键是潜在病因的治疗。
    UNASSIGNED: Chylous ascites is an uncommon form of ascites characterized by milky fluid rich in triglycerides. It is associated with poor lymphatic drainage. We report a case of chylous ascites revealing a follicular lymphoma.
    METHODS: A 73-year-old man presented with a 6-month history of abdominal distension attributed to a chylous ascitis. The thoraco-abdomino-pelvic CT scan revealed voluminous intra- and retroperitoneal mass inseparable from the duodeno-pancreatic block and encompassing the mesenteric vessels, inferior vena cava and renal vessels; abundant ascites and multiple mediastinal, coeliomesenteric, retroperitoneal, iliac and inguinal adenomegalia. The diagnosis of follicular lymphoma was retained through a radio-guided biopsy of the retroperitoneal mass. The patient had weekly paracentesis and immuno-chemotherapy. The course was unfavorable, marked by infection of the ascites fluid after two cycles of immuno-chemotherapy. Our patient developed severe sepsis and died.
    UNASSIGNED: Chylous ascites in conjunction with follicular lymphoma is an exceptional presentation. The pathophysiological mechanism is an impediment to subdiaphragmatic lymphatic drainage caused by external pressure, leading to leakage of dilated subserosal lymphatic ducts into the peritoneal cavity. Histological confirmation is fundamental to manage chylous ascites resulting from lymphomas.
    CONCLUSIONS: Chylous ascites revealing lymphoma is a unique condition. The key to management is the treatment of the underlying etiology.
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  • 文章类型: Case Reports
    淋巴管瘤很罕见,无痛,婴儿期或儿童早期的良性肿瘤,由先天性淋巴管畸形引起,临床表现不同。我们报告了一个六岁的男孩,他的舌头表面有一个微结节,一种灼热的感觉,吞咽和咀嚼期间的困难,以及言语干扰。切除的舌头标本的组织学检查显示,固有层的血管瘤性病变包括许多宽的薄壁空间。MRI检查显示T2信号最大直径为2-3cm的不同区域,在舌头的中部和左前部分具有囊性纹理。病变被诊断为淋巴管瘤,并通过术前栓塞和手术进行治疗。舌淋巴管瘤可能会导致美学问题,功能问题(如吞咽困难,气道阻塞,和言语困难),心理障碍,口腔卫生差,偶尔出血与口腔创伤有关。大部分患者也会经历感染,通常导致病变大小的显着增加。术前栓塞和手术切除的组合可以选择考虑其大尺寸和患者的年龄,并进一步消除复发的可能性。早期诊断和根治性治疗在其管理中至关重要。
    Lymphangiomas are rare, painless, benign tumors in infancy or early childhood resulting from a congenital malformation of the lymphatic vessels with variable clinical appearance. We report the case of a six-year-old male child who presented with a micronodular surface of the tongue, a burning sensation, difficulties during swallowing and mastication, as well as speech disturbances. Histological examination of the excised tongue specimen showed an angiomatous lesion of the lamina propria that comprised many wide thin-walled spaces. MRI examination revealed an area of disparate T2 signal maximum diameter of 2-3 cm with cystic texture in the middle and frontal left part of the tongue. The lesion was diagnosed as a lymphangioma and was managed through pre-operative embolization and surgery. Tongue lymphangiomas may lead to aesthetic problems, functional issues (like dysphagia, airway obstruction, and speech difficulties), psychological disturbances, poor oral hygiene, and occasional bleeding associated with oral trauma. A major fraction of patients also experience infections, often leading to a significant increase in lesion size. A combination of preoperative embolization and surgical excision could be chosen considering its large size and the age of the patient, and to further eliminate the possibility of recurrence. Early diagnosis and radical treatment are critical in its management.
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  • 文章类型: Journal Article
    淋巴管瘤是影响淋巴系统的良性先天性缺陷。这些病变通常累及头颈部,主要是后颈三角。淋巴管瘤在上呼吸道引起阻塞性症状,并引起患者的美学关注。临床上,这些病变被视为宫颈肿胀,并通过超声检查做出明确诊断,计算机断层扫描,和组织病理学分析。在这里,作者介绍了一个不寻常的病例,即一个18个月大的儿童,其右侧表现为巨大的宫颈肿胀,并延伸至颈动脉三角形(包括颈部大血管)以及单侧颈部和筋膜毁容。对患者进行了手术治疗,并完全切除了肿块,并获得了出色的美学效果。
    一名18个月大的孩子从出生起就被带到我们教学医院的小儿外科,右侧有一个巨大的宫颈肿块。在完成实验室和成像(计算机断层扫描)诊断方式的工作后,患者准备接受明确治疗。我们的团队通过右颈曲棍球棒切口接近肿块,随着神经血管束的保存,肿块被完全切除。病人两次随访12个月,具有出色的美学效果,没有复发。
    局限于颈后三角的淋巴管瘤是儿童的常见问题。病变延伸到颈部前部,尤其是那些涉及颈部神经血管束的,是不常见的实体。进行硬化治疗或手术切除的决定应该是合理的,前提是,在手术过程中,保留了神经血管束,并且没有一个重要器官(神经血管成分)得到补偿,以达到完全切除的目的。
    Lymphangiomas are benign congenital defects affecting the lymphatic system. These lesions commonly involve the head and neck, predominantly the posterior cervical triangle. Lymphangiomas cause obstructive symptoms in the upper airway and pose an esthetic concern to the patient. Clinically, these lesions are seen as cervical swelling, and a definite diagnosis is made by ultrasonography, computerized tomography scanning, and histopathologic analysis. Herein, the author present an unusual case of an 18-month-old child presenting with a huge cervical swelling on the right side with extension to the carotid triangle (encompassing neck great vessels) as well as unilateral neck and fascial disfigurement. The patient was treated surgically with the complete excision of the mass and followed up with an excellent esthetic result.
    UNASSIGNED: An 18-month-old child was brought to our teaching hospital\'s pediatric surgery department with a huge cervical mass on the right side since birth. Following the completion of work-up with the laboratory and imaging (computerized tomography scan) diagnostic modalities, the patient was prepared for definite treatment. Our team approached the mass through a right neck hockey stick incision, and with the preservation of the neurovascular bundle, the mass was completely excised. The patient was followed up for 12 months on two occasions, with excellent esthetic results and no relapse.
    UNASSIGNED: Lymphangiomas confined to the posterior cervical triangle are a common problem in children. Lesions extending to the anterior of the neck, especially those involving the neck neurovascular bundle, are uncommon entities. The decision to proceed with sclerotherapy or surgical excision should be justified, provided that, during the surgical procedure, the neurovascular bundle is preserved and none of the vital organs (neurovascular components) are compensated with the goal of a complete mass excision.
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  • 文章类型: Case Reports
    未经证实:我们提供一例25岁女性乳糜池增大的病例报告。诊断是在常规腹部超声检查中进行的,然后通过对比增强MRI进行验证。
    未经证实:超声显示,分叶状,消声囊结构薄,光滑的墙壁,缺乏任何固体成分。病灶位于腹膜后间隙,在胰头下面,在部分压缩的下腔静脉和主动脉之间,几乎延伸到主动脉分叉。我们进行了对比增强的MRI检查,证实了超声检查怀疑乳糜池大,显示与胸导管连续性的非增强性囊性病变。
    未经证实:解剖学,讨论了乳糜池的超声和磁共振表现以及鉴别诊断。
    UNASSIGNED: We present a case report of enlarged cisterna chyli in a 25-year-old woman. The diagnosis was made during a routine abdominal ultrasound examination and afterwards verified with contrast-enhanced MRI.
    UNASSIGNED: Ultrasound revealed a large, lobulated, anechoic cystic structure with thin, smooth walls, lacking any solid components. The lesion was located in the retroperitoneal space, beneath the head of the pancreas, between the partially compressed inferior vena cava and the aorta, extending almost to the aortic bifurcation. We performed a contrast-enhanced MRI examination which confirmed the sonographic suspicion of enlarged cisterna chyli, showing a non-enhancing cystic lesion in continuity with the thoracic duct.
    UNASSIGNED: Anatomy, sonographic and magnetic resonance appearance of cisterna chyli as well as differential diagnosis are discussed.
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  • 文章类型: Journal Article
    未经证实:淋巴管瘤是罕见的,淋巴增生引起的先天性畸形。超过90%的病例发生在2岁以下的儿童中。囊性淋巴管瘤通常发生在颈部和腋窝区域,很少延伸到纵隔。
    未经授权:我们介绍一例中年妇女,表现为呼吸困难和发热咳嗽。胸部X线显示右下内侧肺混浊,胸部CT扫描显示纵隔囊性肿块,侵犯上腔静脉并接近气管和主支气管。进行了胸前切开术和肿瘤切除术以缓解压迫症状。最终病理报告证实诊断为纵隔淋巴管瘤。
    未经证实:当胸部X线检查发现纵隔增宽时,应将淋巴管瘤视为鉴别诊断之一。应该通过CT扫描和活检进一步检查。周围结构的浸润可引起压迫症状,并且还可使手术切除更具挑战性。
    结论:淋巴管瘤是儿科人群的良性肿瘤,很少发生在中年成年人中。即使在没有任何症状的情况下,也必须调查在胸部X射线图像上看到的纵隔增大,纵隔淋巴管瘤可以生长到累及附近的解剖结构。虽然是良性的,淋巴管瘤应在诊断时切除,以避免预期的并发症和解剖结构受压导致呼吸困难,声音嘶哑和上腔静脉综合征。完整的手术切除是治疗的主要手段,并提供良好的术后预后。
    UNASSIGNED: Lymphangiomas are rare, congenital malformations arising from lymphatic hyperplasia. More than 90% of cases are found in children under 2 years of age. Cystic lymphangiomas usually occur in the neck and axillary region and only rarely extend to the mediastinum.
    UNASSIGNED: We present the case of a middle-aged woman who presented with dyspnoea and productive cough. A chest x-ray showed right lower medial lung opacity, and a CT scan of the thorax showed a cystic mediastinal mass, encroaching on the superior vena cava and approaching the trachea and mainstem bronchus. An anterior thoracotomy with tumour resection was performed to relieve compression symptoms. The final pathology report confirmed the diagnosis of mediastinal lymphangioma.
    UNASSIGNED: Lymphangioma should be considered as one of the differential diagnoses when mediastinal widening is found on chest x-ray, and it should be investigated further with a CT scan and biopsy. Infiltration of surrounding structures can cause compression symptoms and can also make surgical resection more challenging.
    CONCLUSIONS: Lymphangiomas are benign tumours of the paediatric population that can rarely occur in middle-aged adults as an acquired form.It is essential to investigate mediastinal enlargement seen on chest x-ray images even in the absence of any symptoms, as mediastinal lymphangiomas can grow to involve nearby anatomical structures.Although benign, lymphangiomas should be excised at the time of diagnosis to avoid anticipated complications and compression of anatomical structures causing respiratory difficulty, hoarseness and superior vena cava syndrome.Complete surgical resection is the mainstay of treatment and provides an excellent postoperative prognosis.
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