一只8岁的Pygora母鹿被赠送给加州大学戴维斯分校,兽医教学医院由于2周的面部肿胀不愈合。尽管接受了治疗,但病变仍在增长,导致咀嚼不适,右鼻通道几乎没有气流,导致了安乐死.粗略检查,发现了一个大的面部肿块,有通过皮肤和硬腭的引流道。在截面上,质量是棕色粉红色的,同质,而且易碎.在肺和肾脏中发现了脓肿样肿块。面部的组织病理学,包括口腔和鼻腔,唾液腺,和淋巴结,以及肺部和肾脏的病变,显示大面积坏死,有许多宽带状,大部分是无菌的,真菌菌丝与合子菌一致。对福尔马林固定的真菌生物进行PCR,面部石蜡包埋的组织确定了Mucorales和曲霉属的Lichtheimiacorymbifera(以前称为Absidiacorymbifera)。怀疑病变是由于真菌鼻炎或牙科饲料嵌塞而开始的,随后扩散到面部并全身扩散到肺和肾脏。我们在这里描述了与山羊面部毛霉菌病相关的病变,并提供了兽医物种中的紫草菌感染和山羊中的真菌感染的文献综述。
An 8-y-old Pygora doe was presented to the University of California-Davis, Veterinary Medical Teaching Hospital because of non-healing facial swelling of 2-wk duration. The lesion grew despite medical treatment, causing discomfort masticating, little-to-no airflow from the right nasal passage, and led to euthanasia. On gross examination, a large facial mass with a draining tract through the skin and hard palate was identified. On section, the mass was brown-pink, homogeneous, and friable. Abscess-like masses were identified in the lungs and kidney. Histopathology of the face, including oral and nasal cavities, salivary glands, and lymph nodes, as well as the lung and kidney lesions, revealed large areas of necrosis with numerous wide ribbon-like, mostly aseptate, fungal hyphae consistent with zygomycetes. PCR for fungal organisms performed on formalin-fixed, paraffin-embedded tissue from the face identified Lichtheimia corymbifera (formerly Absidia corymbifera) of the order Mucorales and an Aspergillus sp. The lesion was suspected to have started either as a fungal rhinitis or dental feed impaction, subsequently spreading to the face and systemically to the lungs and kidney. We describe here the lesions associated with facial mucormycosis in a goat and present a literature
review of L. corymbifera infection in veterinary species and fungal infections in goats.