Reinke's水肿(RE)是声带的良性病理性非炎性病症,临床表现广泛。我们的目的是调查莱因克水肿与一些常见的吸入剂滥用之间的关系。在这项病例对照研究中,主观包括23例RE患者(病例),和50例鼻窦炎患者(对照组)在耳鼻咽喉科接受手术,2015年至2020年。人口特征,一些相关疾病的历史,方法,和香烟的持续时间,鸦片消费是通过病人档案收集的。进行卡方(χ²)检验,分析分类和分类的差异,独立样本T检验用于比较来自无关组的两个样本均值。显著水平(P值)被认为小于0.05。平均年龄为54±12岁,42±11年,分别用于莱因克水肿和鼻窦炎。更多的妇女被记录在RE组,与男人相比。过敏,无原则地使用声音和健谈,喉部手术史,疾病类型与RE相关(p<0.05)。此外,吸烟与莱因克水肿显著相关。平均每天的香烟数量,吸烟的持续时间,RE中鸦片的消耗频率更高(P<0.05)。90%的RE和4%的鼻窦炎患者是鸦片消费者。两组病例和对照组的物质使用方法差异有统计学意义(p<0.0001)。在不同的方法中,扑克和石头方法是最常见的(69.6%),鸦片烟斗是第二常见的方法。这项研究还证实了吸烟和吸入阿片类药物在咽喉病变形成中的危险作用。特别是,长期使用这些物质会带来更严重的副作用。因此,似乎对阿片类药物上瘾的人应该定期访问和咨询,以减少和停止使用它们。
Reinke\'s edema (RE) is a benign pathological non-inflammatory disorder of the vocal folds with a wide range of clinical manifestations. We aim to investigate the relationship between Reinke\'s edema and some common inhalant abuse. In this
case-control study, subjective consisted of 23 patients with RE (the cases), and 50 patients with sinusitis (control) who underwent surgery in the Department of Otolaryngology, between 2015 and 2020. Demographic characteristics, history of some related disease, methods, and the duration of cigarette, and opium consumption were collected through the patients\' files. The chi-square (χ²) test was run to analyze the differences in the categorical and, and the Independent Sample T-test was used to compare two sample means from unrelated groups. A significant level (p-value) was considered less than 0.05. The mean age was 54 ± 12 years, and 42 ± 11 years, respectively for Reinke\'s edema and sinusitis. More women had been recorded in the RE group, compared to men. Allergy, unprincipled use of voice and talkativeness, history of laryngeal surgery, and type of disease were correlated to RE (p < 0.05). Also, cigarette smoking was significantly correlated with Reinke\'s edema. The average number of cigarettes per day, the duration of smoking, and opium consumption were more frequent in RE (P < 0.05). 90% of the RE and 4% of sinusitis patients were opium consumers. There was a statistically significant difference in the methods of substance use in the two groups of cases and control (p < 0.0001). Among the different methods, the poker and stone method was the most common (69.6%), and the opium smoking pipe was the second most common method. This study also confirmed the hazardous effects of smoking and inhaling opiates in the formation of lesions of the pharynx and
larynx. In particular, longer use of these substances will be associated with more serious side effects. Therefore, it seems that people who are addicted to opiates should undergo periodic visits and counseling to reduce and stop their use.