Intervertebral disc degeneration

椎间盘退变
  • 文章类型: English Abstract
    Recently, the percutaneous endoscopic lumbar interbody fusion (PELIF) technique has become the most representative minimally invasive technique in spinal surgery. PELIF is widely used in the treatment of various degenerative diseases of the lumbar spine. However, this technique has a long learning curve with adverse consequences for the patient if the surgeon is unsure of the indications and contraindications of this technique. There is currently no expert consensus on PELIF in spinal surgery in China. To standardize the application of this technique in various diseases of the lumbar spine in China, the Chinese Study Group of Minimal Invasive Spinal Surgery, Chinese Association of Spine and Spinal Cord, and Chinese Study Group for Lumbar Spine, Chinese Association of Spine and Spinal Cord, of the Chinese Association of Rehabilitation Medicine have taken the lead in developing this Chinese expert consensus on the application PELIF through a modified Delphi survey study method for the reference of our colleagues. The consensus covers the following aspects of the PELIF: indications and contraindications, advantages and disadvantages, preoperative evaluation, anesthesia methods and surgical procedures, treatment and prevention of complications, and postoperative follow-up.
    近年来,脊柱内镜辅助下腰椎椎体间融合术(PELIF)已成为脊柱外科最具代表性的微创技术,被广泛应用于各类腰椎退行性疾病的治疗之中。然而,该技术具有较长的学习曲线,且手术医生对该技术的适应证和禁忌证把握不准时,可能会给患者带来相应的不良后果。目前我国脊柱外科专业尚无脊柱PELIF技术相关专家共识。为规范该技术在国内腰椎各类疾病中的应用,由中国康复医学会脊柱脊髓损伤专业委员会脊柱微创学组及脊柱脊髓专业委员会腰椎研究学组牵头,通过改良Delphi调查研究法制定了本共识,以供广大同道参考。本共识内容包括PELIF技术的适应证与禁忌证、优势和劣势、术前评估、麻醉方式及手术操作、并发症处理及预防和术后随访。.
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  • 文章类型: Journal Article
    UNASSIGNED:使用改进的德尔菲法建立共识。利益攸关方和专家应邀参加了专家小组。向小组分发了最佳做法声明和决策问卷。小组成员被要求在几轮的一系列声明后将“强烈不同意”标记为“强烈同意”,直到达成共识或决策方法被认为不适合达成共识。腰椎疼痛最常见的原因是椎间退化,导致椎间盘退行性疾病和腰椎间盘突出症。在适当的患者协议和对韩国医疗保健的康复期望方面缺乏一致意见。韩国医疗的长期可行性,在机构环境中进一步采用,和特定的患者结果取决于是否存在适当的韩国医疗计划。由17名从业者组成的韩国医学专家小组采用了改良的Delphi方法,以就韩国腰椎间盘突出症的医疗护理达成共识。该小组首先回顾了与韩国腰椎间盘突出症药物治疗相关的文献和指南。小组成员考虑了旨在为具有广泛腰椎间盘突出症症状的患者确定“标准化”韩国医疗建议的问卷。每个小组成员都参加了一轮投票,随后是在线意见收集会议。共识被定义为受访者之间≥75%的共识。在第一轮中,对专家小组进行了5个领域的144份问卷。在审查了第一轮收集的答复和不限成员名额的评论后,作者将问卷修改为53项并继续进行.在第2轮中,所有53个调查问题都达成了共识。最终的治疗途径包括在4种类型的医疗机构中对腰椎间盘突出症进行标准化和全面的护理方法。这项研究确定了一套基于证据和共识的核心原则,这些原则对于全面的护理模式至关重要。纳入识别,转介,腰椎间盘突出症患者的治疗。
    UNASSIGNED: A modified Delphi method was used to establish a consensus. Stakeholders and experts were invited to participate in the expert panel. Best practice statements and decision-making questionnaires were distributed to the panel. Panel members were asked to mark \"Strongly disagree\" to \"Strongly agree\" after a series of statements over several rounds until either a consensus was reached or the decision-making method was deemed unsuitable for reaching a consensus.The most common cause of lumbar pain is intervertebral degeneration, which leads to degenerative disc disease and lumbar disc herniation. There is a lack of unanimity regarding appropriate patient protocols and rehabilitation expectations for Korean medical care. The long-term viability of Korean medical treatment, further adoption in the institutional setting, and specific patient outcomes are contingent on the existence of appropriate Korean medical programs.A Korean medical expert panel of 17 practitioners employed a modified Delphi method to achieve consensus on Korean medical care for lumbar disc herniation. The panel first reviewed the literature and guidelines relevant to Korean medical treatment for lumbar disc herniation. The panel members considered questionnaires intended to determine \"standardized\" Korean medical care recommendations for patients with a wide range of symptoms of lumbar disc herniation. Each panel member participated in a round of voting, which was followed by an opinion-collecting session online. Consensus was defined as a ≥75% agreement among the respondents.In the first round, 144 questionnaires across 5 domains were administered to the expert panels. After reviewing the responses and open-ended comments collected in the first round, the authors modified the questionnaires to 53 items and proceeded. In round 2, consensus was achieved in all 53 survey questions. The final treatment pathway comprised a standardized and comprehensive care approach for lumbar disc herniations in 4 types of medical institutions.This study identified a core set of evidence- and consensus-based principles that are essential to a comprehensive model of care, incorporating identification, referral, and management of patients with lumbar disc herniation.
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  • 文章类型: Journal Article
    Degenerative disease of the spine, in the form of intervertebral disc degeneration and bony growth, causing osteophytes and impinging upon the spinal canal and neural foramina, is the most frequent disorder affecting the spine. In this chapter we first discuss briefly the indications for computed tomography or magnetic resonance imaging in suspected degenerative spine disease. We then describe changes of disc height, signal intensity, and disc contour with aging and repeated microtrauma, as well as the imaging techniques most appropriate to image them. A grading system for lumbar disc changes is provided. Stenosis of the canal and neural foramina is reviewed next, concluding with a description of degenerative changes affecting the vertebral endplates and bone marrow.
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  • 文章类型: Journal Article
    最近提出了四个MRI变量与胸腰椎椎间盘突出或突出的诊断独立相关。中线椎间盘突出,部分椎间盘退变与椎间盘突出有关,而单个椎间盘突出和椎间盘材料分散在椎间盘间隙边界之外的存在与椎间盘挤压有关。这次回顾的目的,横断面研究是为了确定使用这些MRI变量是否可以改善胸腰椎椎间盘突出和突出之间的区分。包括80只经手术证实的胸腰椎椎间盘突出或突出的大型犬。随机MRI研究两次向六名失明的观察者进行,分为三个经验类别。在第一次评估中,观察者在没有指导的情况下做出了胸腰椎椎间盘突出或突出的推定诊断。在第二次评估中,他们被要求在指南的帮助下做出推定诊断。Kappa统计对协议进行了评估。使用拟议的指南后,诊断准确性从70.8%显着提高到79.6%,观察者对椎间盘突出或椎间盘突出的诊断的共识从一般(κ=0.27)提高到中等(κ=0.41)。诊断准确性受观察者经验程度的影响很大。观察者对评估变量的同意范围从公平到优秀,观察者之间的同意范围从公平到中等。这项研究的结果表明,拟议的成像指南可以帮助区分胸腰椎椎间盘突出与突出物。
    Four MRI variables have recently been suggested to be independently associated with a diagnosis of thoracolumbar intervertebral disk extrusion or protrusion. Midline intervertebral disk herniation, and partial intervertebral disk degeneration were associated with intervertebral disk protrusion, while presence of a single intervertebral disk herniation and disk material dispersed beyond the boundaries of the intervertebral disk space were associated with intervertebral disk extrusion. The aim of this retrospective, cross-sectional study was to determine whether using these MRI variables improves differentiation between thoracolumbar intervertebral disk extrusions and protrusions. Eighty large breed dogs with surgically confirmed thoracolumbar intervertebral disk extrusions or protrusions were included. Randomized MRI studies were presented on two occasions to six blinded observers, which were divided into three experience categories. During the first assessment, observers made a presumptive diagnosis of thoracolumbar intervertebral disk extrusion or protrusion without guidelines. During the second assessment they were asked to make a presumptive diagnosis with the aid of guidelines. Agreement was evaluated by Kappa-statistics. Diagnostic accuracy significantly improved from 70.8 to 79.6% and interobserver agreement for making a diagnosis of intervertebral disk extrusion or intervertebral disk protrusion improved from fair (κ = 0.27) to moderate (κ = 0.41) after using the proposed guidelines. Diagnostic accuracy was significantly influenced by degree of observer experience. Intraobserver agreement for the assessed variables ranged from fair to excellent and interobserver agreement ranged from fair to moderate. The results of this study suggest that the proposed imaging guidelines can aid in differentiating thoracolumbar intervertebral disk extrusions from protrusions.
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  • 文章类型: Journal Article
    Interbody fusion techniques have been promoted as an adjunct to lumbar fusion procedures in an effort to enhance fusion rates and potentially improve clinical outcome. The medical evidence continues to suggest that interbody techniques are associated with higher fusion rates compared with posterolateral lumbar fusion (PLF) in patients with degenerative spondylolisthesis who demonstrate preoperative instability. There is no conclusive evidence demonstrating improved clinical or radiographic outcomes based on the different interbody fusion techniques. The addition of a PLF when posterior or anterior interbody lumbar fusion is performed remains an option, although due to increased cost and complications, it is not recommended. No substantial clinical benefit has been demonstrated when a PLF is included with an interbody fusion. For lumbar degenerative disc disease without instability, there is moderate evidence that the standalone anterior lumbar interbody fusion (ALIF) has better clinical outcomes than the ALIF plus instrumented, open PLF. With regard to type of interbody spacer used, frozen allograft is associated with lower pseudarthrosis rates compared with freeze-dried allograft; however, this was not associated with a difference in clinical outcome.
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  • 文章类型: Journal Article
    为腰背痛患者制定适当的治疗策略,在没有狭窄或脊椎滑脱的情况下,仍然是一个有争议的话题。这种情况所固有的通常是无法充分识别下腰痛的来源,以证明各种治疗建议的合理性。如腰椎融合。目前的证据没有为这些患者确定一个最佳的治疗替代方案。根据一些前景,随机试验,可比较的结果,对于患有1级或2级椎间盘退行性疾病的患者,已在腰椎融合或具有认知元素的综合康复计划后得到证明。在寻求这种替代方案时,有限的机会获得这种全面的康复计划可能会有问题。对于疼痛难以保守治疗的患者,建议腰椎融合术。这些研究的局限性排除了提出支持腰椎融合的最可靠建议的能力。一些质量较低的研究,主要是案例系列,还支持在该患者人群中使用腰椎融合术。
    Establishing an appropriate treatment strategy for patients presenting with low-back pain, in the absence of stenosis or spondylolisthesis, remains a controversial subject. Inherent to this situation is often an inability to adequately identify the source of low-back pain to justify various treatment recommendations, such as lumbar fusion. The current evidence does not identify a single best treatment alternative for these patients. Based on a number of prospective, randomized trials, comparable outcomes, for patients presenting with 1- or 2-level degenerative disc disease, have been demonstrated following either lumbar fusion or a comprehensive rehabilitation program with a cognitive element. Limited access to such comprehensive rehabilitative programs may prove problematic when pursuing this alternative. For patients whose pain is refractory to conservative care, lumbar fusion is recommended. Limitations of these studies preclude the ability to present the most robust recommendation in support of lumbar fusion. A number of lesser-quality studies, primarily case series, also support the use of lumbar fusion in this patient population.
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