■伤寒沙门氏菌,导致伤寒的革兰氏阴性细菌,可感染心脏的内层或瓣膜并引起心内膜炎。本系统评价旨在报道伤寒沙门氏菌相关心内膜炎的病例及其临床特征。
■根据系统评价和荟萃分析(PRISMA)清单的首选报告项目报告本系统评价。只有伤寒沙门氏菌引起的心内膜炎的病例报告和病例系列,不论年龄,性别,和人口统计,被认为有资格列入名单。为了确定相关研究,使用PubMed上的相关关键词进行了文献检索,谷歌学者,和Cochrane图书馆从成立到2023年12月31日。选择研究后,提取相关数据,并按频率和百分比进行汇总.使用JoannaBriggs研究所关键评估清单对病例报告进行了质量评估。
■本综述包括7例病例报告,包括22.2%的女性和77.8%的男性患者。患者的平均年龄为27.9±12.0岁。关于过去的病史,33.3%(3/9)的患者既往有心脏病变。发烧仍然是最常见的抱怨,发生在88.9%的病例中。所有病例均采用经胸和经食管超声心动图诊断,33.3%的人识别二尖瓣上的植被,主动脉,和三尖瓣.头孢曲松,有或没有庆大霉素,88.9%的病例仍然选择抗生素,所有患者对所提供的治疗都有反应。
■S.伤寒相关性心内膜炎,虽然罕见,提出了独特的挑战,需要及时诊断。这项对7例病例的系统评价强调了受影响的主要是男性人群,平均年龄在第三个十年,表明比其他原因有更高的侵入性。这项研究的结果强调了早期识别和适当管理的重要性,主要是抗生素治疗。对更大群体的进一步研究对于完善对这种罕见但危及生命的疾病的理解和指导政策制定至关重要。
UNASSIGNED: Salmonella typhi, a gram-negative bacterium responsible for typhoid fever, can infect the inner lining or valves of the heart and cause endocarditis. This systematic
review aimed to report cases of S. typhi-associated endocarditis and its clinical features.
UNASSIGNED: This systematic
review was reported as per the Preferred Reporting Items for Systematic
Review and Meta-Analysis (PRISMA) checklist. Only case reports and case series of endocarditis caused by S. typhi, irrespective of age, gender, and demographics, were considered eligible for inclusion. To identify relevant studies, a literature search was conducted using relevant keywords on PubMed, Google Scholar, and the Cochrane Library from inception to 31 December 2023. After selecting the studies, the relevant data were extracted and pooled in terms of frequencies and percentages. A quality assessment was performed using the Joanna Briggs Institute Critical Appraisal Checklist for Case Reports.
UNASSIGNED: This
review included seven case reports, comprising 22.2% female and 77.8% male patients. The mean age of patients was 27.9 + 12.0 years. Regarding past medical history, 33.3% (3/9) of patients had a previous cardiac pathology. Fever remained the most common complaint, occurring in 88.9% of cases. Transthoracic and transesophageal echocardiography were used to diagnose all cases, with 33.3% identifying vegetation on the mitral, aortic, and tricuspid valves. Ceftriaxone, with or without gentamycin, remained the choice of antibiotic for 88.9% of cases, and all patients responded to the offered treatment.
UNASSIGNED: S. typhi-associated endocarditis, though rare, presents unique challenges and requires timely diagnosis. This systematic
review of seven cases highlights a predominantly male population affected, with a mean age in the third decade, suggesting a higher invasiveness than other causes. The findings from this study underscore the importance of early recognition and appropriate management, primarily with antibiotic therapy. Further research with larger cohorts is crucial to refine understanding and guide policymaking for this rare but life-threatening condition.