Chinese star anise (
Illicium verum) is a popular herbal remedy for infantile colic. Contamination with a related species of Japanese star anise (
Illicium anisatum) has been related to cases of toxicity in infants. We report the
case of a 3-month-old infant girl who presented to the emergency department with signs and symptoms of toxicity after recent star anise ingestion. Her presentation is consistent with other
reports of toxicity that include particular gastrointestinal and neurological findings. A discussion of the clinical aspects of star anise toxicity, differential diagnosis, and management follows.