Iliac Artery

髂动脉
  • 文章类型: Journal Article
    缺乏证明经桡动脉支架置入术安全性和有效性的大规模多中心研究。我们评估了来自日本多中心数据库的数据。对105例患者的115个病灶进行了经桡动脉支架置入术。进场地点由操作员自行决定。排除了预定的用于双向入路的多个鞘管插入的患者。对其临床资料进行回顾性分析。该队列的平均年龄为71.1±8.3岁。86例患者(81.9%)为男性。糖尿病,高血压,血脂异常,39例(37.1%)存在吸烟习惯,84(80.0%),69(65.7%),78例(74.3%),分别。卢瑟福分类1、2、3、4和5包括40(34.8%),42(36.5%),28(24.3%),3(2.6%),和2(1.7%)病变,分别,而跨大西洋社会间共识II分类A,B,C,D包括74人(64.3%),21(18.3%),15(13.0%),和5(4.3%),分别。27个病变(23.5%)患有慢性完全闭塞。所有病变均用141个支架成功治疗。四名患者(3.8%)需要额外穿刺股动脉以成功植入支架。踝臂指数从0.65±0.17明显改善为0.95±0.15(P<0.0001)。没有患者经历任何手术或进入部位相关的并发症。术后3例(2.9%)出现无症状桡动脉闭塞。1个月时无靶病变血运重建或并发症。与传统的经股动脉入路相比,经桡动脉支架置入术是安全可行的,在精心挑选的患者中没有任何特定的并发症.
    Large-scale multicenter studies demonstrating the safety and effectiveness of transradial iliac artery stenting are lacking. We evaluated the data from a multicenter database in Japan. Transradial iliac artery stenting was performed on 115 lesions in 105 patients. The approach site was determined at the discretion of the operator. Patients with scheduled multiple sheath insertions for the bidirectional approach were excluded. Clinical data were retrospectively analyzed. The average age of this cohort was 71.1 ± 8.3 years. Eighty-six patients (81.9%) were male. Diabetes mellitus, hypertension, dyslipidemia, and smoking habit were present in 39 (37.1%), 84 (80.0%), 69 (65.7%), and 78 patients (74.3%), respectively. Rutherford classifications 1, 2, 3, 4, and 5 comprised 40 (34.8%), 42 (36.5%), 28 (24.3%), 3 (2.6%), and 2 (1.7%) lesions, respectively, while Trans-Atlantic Inter-Society Consensus II classifications A, B, C, and D comprised 74 (64.3%), 21 (18.3%), 15 (13.0%), and 5 (4.3%), respectively. Twenty-seven lesions (23.5%) had chronic total occlusion. All lesions were successfully treated with 141 stents. Four patients (3.8%) required additional puncture of the common femoral artery for successful stent implantation. The ankle-brachial index significantly improved from 0.65 ± 0.17 to 0.95 ± 0.15 (P < 0.0001). None of the patients experienced any procedural or access site-related complications. Asymptomatic radial artery occlusion was observed in three cases (2.9%) after the procedure. There were no target lesion revascularizations or complications at 1 month. Compared to the traditional transfemoral approach, transradial iliac artery stenting is safe and feasible without any specific complications in carefully selected patients.
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  • 文章类型: Journal Article
    髂动脉支架成形术是治疗主髂动脉闭塞性疾病的有效替代治疗方式。很少有随机对照试验比较自膨式支架(SES)和球囊扩张式支架(BES)在动脉粥样硬化性髂动脉疾病中的疗效和安全性。在这个随机的,多中心研究,普通或髂外动脉闭塞性疾病患者以1∶1的比例随机分配至BES或SES组.主要终点是1年临床通畅,定义为由于索引程序后目标病变的再狭窄而免于任何手术或经皮干预。次要终点是1年主要不良临床事件的复合事件。来自韩国17个主要心血管干预中心的201例患者被纳入。入选患者的平均年龄为66.8±8.5岁,86.2%的参与者为男性。严重肢体缺血的发生率为15.4%,最常见的靶病变是髂总动脉(75.1%)。作为主要终点,作为主要终点的1年临床通畅率,BES组为99%,SES组为99%(p>0.99).BES组1年重复血运重建率为7.8%,SES组为7.0%(p=0.985;置信区间,1.011[0.341-2.995])。在我们的随机研究中,在12个月的临床结局中,使用自膨式支架与球囊扩张式支架治疗髂动脉闭塞性疾病具有可比性,无论在远端主动脉髂动脉闭塞性病变中的部署方法如何,手术成功率或地理错失率都没有差异(ClinicalTrial.gov,NCT01834495)。
    Iliac artery angioplasty with stenting is an effective alternative treatment modality for aortoiliac occlusive diseases. Few randomized controlled trials have compared the efficacy and safety between self-expandable stent (SES) and balloon-expandable stent (BES) in atherosclerotic iliac artery disease. In this randomized, multicenter study, patients with common or external iliac artery occlusive disease were randomly assigned in a 1:1 ratio to either BES or SES. The primary end point was the 1-year clinical patency, defined as freedom from any surgical or percutaneous intervention due to restenosis of the target lesion after the index procedure. The secondary end point was a composite event from major adverse clinical events at 1 year. A total of 201 patients were enrolled from 17 major cardiovascular intervention centers in South Korea. The mean age of the enrolled patients was 66.8 ± 8.5 years and 86.2% of the participants were male. The frequency of critical limb ischemia was 15.4%, and the most common target lesion was in the common iliac artery (75.1%). As the primary end point, the 1-year clinical patency as primary end point was 99% in the BES group and 99% in the SES group (p > 0.99). The rate of repeat revascularization at 1 year was 7.8% in the BES group and 7.0% in the SES group (p = 0.985; confidence interval, 1.011 [0.341-2.995]). In our randomized study, the treatment of iliac artery occlusive disease with self-expandable versus balloon-expandable stent was comparable in 12-month clinical outcomes without differences in the procedural success or geographic miss rate regardless of the deployment method in the distal aortoiliac occlusive lesion (ClinicalTrials.gov, NCT01834495).
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  • 文章类型: Journal Article
    目的:下腰椎前路手术的一个重要并发症是血管损伤。动脉和静脉血管的大小和起源各不相同,这可能会限制手术区域并在特定情况下损害安全性。我们旨在探讨腹膜后脉管系统与下脊柱前表面之间的关系,并建立有助于预测L4-L5和L5-S1水平椎间盘前入路的相关性的值。
    方法:该研究包括13具新鲜的人类尸体。在探查腹腔并切除内脏器官后,脉管系统,和脊柱前表面显示在肾周筋膜下部延伸下方。获得了大血管和椎间盘的形态测量。分析所有测量值并表示为平均值和标准偏差。评估了两性之间的数值差异。
    结果:L4-L5和L5-S1椎间盘的前高度分别为6.8±0.81mm和6.7±0.99mm,分别。主动脉的宽度,下腔静脉,左右髂总动脉,对,左髂总静脉分别为16.4±3.58,20.6±3.36,11.5±2.32,11.5±2.43,14.7±3.13,15.5±3.27mm,分别。平均主动脉分叉角度为45.5°。在53.8%的尸体中,主动脉分叉位于L4椎骨的下终板上方。动脉间和髂间三角区面积分别为14.6±5.33cm2和7.1±4.35cm2。性别之间没有统计学上的显着差异。
    结论:手术前应进行详细的血管放射学检查,以避免前路手术中不必要的血管并发症。了解动脉间和髂间三角形的面积以及主动脉分叉位置可以帮助评估安全工作区。
    OBJECTIVE: To explore the relationship between the retroperitoneal vasculature and anterior surface of the lower spine, and to establish values for aiding in prediction of the pertinence of anterior approach at the L4-L5 and L5-S1 intervertebral discs.
    METHODS: The study included 13 fresh human cadavers. After exploration of the abdominal cavity and removal of the visceral organs, the vasculature, and anterior spinal surface were revealed beneath the lower extension of the perirenal fascia. Morphometric measurements of the great vessels and the intervertebral discs were obtained. All measurements were analyzed and presented as mean and standard deviation. Differences in the values between sexes were assessed.
    RESULTS: The anterior height of the L4-L5 and L5-S1 intervertebral disc was 6.8 ± 0.81 mm and 6.7 ± 0.99 mm, respectively. The widths of the aorta, inferior vena cava, right and left common iliac arteries, and right, and left common iliac veins were 16.4 ± 3.58, 20.6 ± 3.36, 11.5 ± 2.32, 11.5 ± 2.43, 14.7 ± 3.13, and 15.5 ± 3.27 mm, respectively. The mean aortic bifurcation angle was 45.5°. The aortic bifurcation was located above the lower endplate of the L4 vertebrae in 53.8% of the cadavers. The area of the interarterial and interiliac trigones was 14.6 ± 5.33 cm < sup > 2 < /sup > and 7.1 ± 4.35 cm2, respectively. No statistically significant differences were noted between the sexes.
    CONCLUSIONS: An elaborate radiological examination of the vasculature should be performed prior to surgery to avoid unwanted vascular complications during the anterior approach. Knowing the area of the interarterial and interiliac triangles and the aortic bifurcation location could be aid in assessing the safe working zone.
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  • 文章类型: Journal Article
    目的:旋髂深动脉皮瓣(DCIA)和带血管腓骨游离皮瓣(FFF)是上颌骨缺损重建的主要皮瓣。这项研究比较了这些皮瓣的功能结果和成功率,以提供中面重建策略。
    方法:在口腔颌面外科用DCIA或FFF重建上颌骨缺损,回顾性分析2016年5月至2023年5月北京大学口腔医院的临床资料。长度,宽度,和移植骨节段的高度;颌间距离;支持重建率(BRR);牙弓重建率(DAR);成功率;和牙种植率。
    结果:DCIA和FFF组有33和27例患者,分别。DCIA组成功率为93.94%,FFF组为100%。DCIA的长度小于FFF的长度;但是,宽度和高度明显较大。DCIA组中87.10%的病例分为布朗B级和C级,FFF组中51.85%的病例被归类为布朗d级。DCIA组的平均BRR为69.89%±16.05%,显著高于FFF组。DCIA和FFF组中共有38.7%和11.1%的患者,分别,已完成植入。
    结论:DCIA具有更大的宽度和高度,更适合修复棕色B级和C级缺陷,提供足够的骨植入,而FFF较长,更适合布朗D类缺陷重建。
    OBJECTIVE: The deep circumflex iliac artery flap (DCIA) and vascularized fibular free flap (FFF) are mainstay flaps for maxillary defect reconstruction. This study compared the functional outcomes and success rates of these flaps to provide midface reconstruction strategies.
    METHODS: Maxillary defects reconstructed with DCIA or FFF at the Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology between May 2016 and May 2023 were retrospectively analyzed. The length, width, and height of the grafted bone segments; intermaxillary distance; buttress reconstruction rate (BRR); dental arch reconstruction rate (DAR); success rate; and dental implantation rate were compared.
    RESULTS: The DCIA and FFF groups had 33 and 27 patients, respectively. Success rate in the DCIA group was 93.94 % and 100 % in the FFF group. The DCIA length was less than that of FFF; however, the width and height were significantly larger. 87.10 % of cases in the DCIA group were classified as Brown class b and c, 51.85 % of cases in the FFF group were classified as Brown class d. The average BRR in the DCIA group was 69.89 % ± 16.05 %, which was significantly higher than that in the FFF group. A total of 38.7 % and 11.1 % patients in the DCIA and FFF groups, respectively, had completed implantation.
    CONCLUSIONS: DCIA has a greater width and height, and is more suitable for repairing Brown class b and c defects, providing sufficient bone for implantation, while the FFF is longer and more suitable for Brown class d defect reconstruction.
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  • 文章类型: Journal Article
    目的:本研究的目的是确定髂股动脉轴的屈曲点位置及其角度。
    方法:对37例动态数字减影血管造影进行分析,并纳入本研究。测量了不同的长度,基于特定的解剖标志:髂外动脉的起源,腹股沟韧带和股动脉分叉。在髋部的伸展和屈曲期间测量这些长度,以便确定动脉的屈曲点。
    结果:在扩展中,测量了髂外动脉的一些生理角度。在髋关节屈曲时,从扭结点到髂总动脉分叉的距离分别为右侧82±21mm(范围48-116)和左侧95±20mm(范围59-132)。从扭结点到腹股沟韧带的距离分别为右侧38±40mm(范围12-138)和左侧26±23mm(范围8-136)。从扭结点到股动脉分叉的距离分别为右侧45±29mm(范围15-107)和左侧27±12mm(范围10-66)。在屈曲期间,髂股轴屈曲点的角度为114±18°(范围81-136°)。
    结论:屈曲点位于颅骨腹股沟韧带和髂外动脉的下方。
    OBJECTIVE: The aim of the study was to determine the flexion point\'s location of the ilio-femoral arterial axis and its angulation.
    METHODS: Thirty-seven dynamic digital subtraction angiographies were analyzed and were included in the current study. Different lengths were measured, based on specific anatomical landmarks: the origin of the external iliac artery, the inguinal ligament and the bifurcation of the femoral artery. These lengths were measured in extension and during flexion of the hip in order to determine the flexion point of the artery.
    RESULTS: In extension, some physiological angulations of the external iliac artery were measured. During flexion of the hip joint, the distance from the kink point to the bifurcation of the common iliac artery was respectively 82 ± 21 mm (range 48-116) on the right side and 95 ± 20 mm (range 59-132) on the left side. The distance from the kink point to the inguinal ligament was respectively 38 ± 40 mm (range 12-138) on the right side and 26 ± 23 mm (range 8-136) on the left side. The distance from the kink point to the bifurcation of the femoral artery was respectively 45 ± 29 mm (range 15-107) on the right side and 27 ± 12 mm (range 10-66) on the left side. During flexion, the angulation of the flexion point of the ilio-femoral axis was 114 ± 18° (range 81-136°).
    CONCLUSIONS: The flexion point was located cranially to the inguinal ligament and below the departure of the external iliac artery.
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  • 文章类型: Journal Article
    目的:腔内修复术是治疗主髂动脉瘤的首选方法,建议保留至少一条髂内动脉。本研究旨在评估来自全球Iliac分支研究(GIBS,NCT05607277)提高髂支装置(IBD)的选择标准并改善长期结果。
    方法:对297例GIBS患者行动脉瘤腔内修复术的治疗前CT扫描结果进行分析。测量包括髂动脉总长,髂总动脉长度,弯曲指数,髂总动脉张开角,髂内动脉狭窄,钙化评分,和设备着陆区的直径。统计测试评估了解剖测量和IBD介导的髂内动脉保存的差异。
    结果:左侧髂总动脉长度短于右侧(6.7mm,P=.0019);右髂总动脉不那么曲折(P=.0145)。男性左髂总动脉弯曲较大(P=.0475),左髂内动脉着陆区直径较大(P=.0453)。保留在权利上更为常见(158单方面,34双边)比左(105单边,34双边)。有192个右侧和139个左侧IBD,男性318例IBD,女性13例。
    结论:本研究提供了接受IBDs血管内修复的患者的治疗前全面的髂关节解剖分析,强调双方和性别之间的差异。这些发现可以改善IBD患者的选择,可能增强主动脉髂动脉瘤治疗的结果。然而,研究中女性人数有限,这突显了需要进一步研究以推广跨性别的发现。
    OBJECTIVE: Endovascular repair is the preferred treatment for aortoiliac aneurysm, with preservation of at least one internal iliac artery recommended. This study aimed to assess pre-endovascular repair anatomical characteristics of aortoiliac aneurysm in patients from the Global Iliac Branch Study (GIBS, NCT05607277) to enhance selection criteria for iliac branch devices (IBD) and improve long-term outcomes.
    METHODS: Pre-treatment CT scans of 297 GIBS patients undergoing endovascular aneurysm repair were analyzed. Measurements included total iliac artery length, common iliac artery length, tortuosity index, common iliac artery splay angle, internal iliac artery stenosis, calcification score, and diameters in the device\'s landing zone. Statistical tests assessed differences in anatomical measurements and IBD-mediated internal iliac artery preservation.
    RESULTS: Left total iliac artery length was shorter than right (6.7 mm, P = .0019); right common iliac artery less tortuous (P = .0145). Males exhibited greater tortuosity in the left total iliac artery (P = .0475) and larger diameter in left internal iliac artery\'s landing zone (P = .0453). Preservation was more common on right (158 unilateral, 34 bilateral) than left (105 unilateral, 34 bilateral). There were 192 right-sided and 139 left-sided IBDs, with 318 IBDs in males and 13 in females.
    CONCLUSIONS: This study provides comprehensive pre-treatment iliac anatomy analysis in patients undergoing endovascular repair with IBDs, highlighting differences between sides and sexes. These findings could refine patient selection for IBD placement, potentially enhancing outcomes in aortoiliac aneurysm treatment. However, the limited number of females in the study underscores the need for further research to generalize findings across genders.
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  • 文章类型: Journal Article
    简介类固醇和抗IL6生物疗法在巨细胞动脉炎(GCA)患者中获得缓解方面非常有效,但复发的风险仍然很高。我们旨在确定GCA复发的预测因子。方法2011年5月至2022年5月,根据2022年美国风湿病学/EULAR(ACR/EULAR)分类标准,所有新诊断为GCA的连续患者均符合本研究的条件。主要结果是36个月随访期间的GCA复发率。分析与主要结局和首次复发时间相关的因素。结果108例患者(74[69-81]年,64.8%的女性)对GCA的新诊断进行了研究。65例(60.2%)患者经活检证实为GCA。诊断时进行的98(90.7%)FDG/PETCT扫描可供审查。所有患者接受类固醇治疗21.0[18.0-28.5]个月,与甲氨蝶呤(n=1,0.9%)或托珠单抗(n=2,1.9%)相关。在27.5[11.4-35.0]个月的中位随访期间,40例(37%)患者出现复发.多变量Cox回归模型,包括一般标志,性别,主动脉壁厚度,动脉壁FDG摄取和静脉类固醇脉冲作为协变量,显示肢体动脉的一般体征(HR2.0[1.0-4.0,p<0.05)和FDG摄取(HR2.7[1.3-5.5],诊断时p<0.01)与GCA复发相关。结论诊断时肢体动脉中FDG的摄取是新诊断GCA复发的预测因素。
    BACKGROUND: Steroids and anti-IL6 biotherapy are highly effective in obtaining remission in patients with giant cell arteritis (GCA) but the risk of relapses remains high. We aimed to identify predictors of relapse in GCA.
    METHODS: All consecutive patients admitted with a new diagnosis of GCA - according to the 2022 American College of Rheumatology/EULAR (ACR/EULAR) classification criteria - between May 2011 and May 2022 were eligible for this study. The primary outcome was the GCA relapse rate over the 36-months follow up. Factors associated with the primary outcome and time to first relapse were analyzed.
    RESULTS: One hundred and eight patients (74 [69-81] years, 64.8% women) with a new diagnosis of GCA were studied. GCA was biopsy-proven in 65 (60.2%) cases. Ninety-eight (90.7%) FDG/PET CT scans performed at diagnosis were available for review. All patients received steroids given for 21.0 [18.0-28.5] months, associated with methotrexate (n=1, 0.9%) or tocilizumab (n=2, 1.9%). During a median follow-up of 27.5 [11.4-35.0] months, relapse occurred in 40 (37%) patients. Multivariable Cox regression model, including general signs, gender, aortic wall thickness, FDG uptake in arterial wall and IV steroid pulse as covariates, showed that both general signs (HR 2.0 [1.0-4.0, P<0.05) and FDG uptake in limb arteries (HR 2.7 [1.3-5.5], P<0.01) at diagnosis were associated with GCA relapse.
    CONCLUSIONS: FDG uptake in limb arteries at diagnosis is a predictor of relapse in newly diagnosed GCA.
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  • 文章类型: Journal Article
    要比较三种(自下而上非芭蕾舞,自上而下的非芭蕾舞,自上而下的芭蕾舞)在腹主动脉瘤的血管内修复中使用的理想化支架移植物配置,在各种流变模型的影响下。
    假定了十个流变模型,并采用了商业有限体积求解器,以模拟现实边界条件下的血流。进行了适当的网格收敛性研究,并计算了五个血液动力学变量:时间平均壁切应力(TAWSS),振荡剪切指数(OSI),相对停留时间(RRT),所有三种构型的内皮细胞激活电位(ECAP)和位移力(DF)。
    血流模型的选择可能会影响结果,但并不构成对假定支架移植物整体性能的重要决定因素。相反,支架移植物的几何形状具有主要影响。具体来说,自下而上的非芭蕾类型的特点是表现最差,表现出最低的TAWSS和最高的OSI,RRT和ECAP值。另一方面,TopDown芭蕾舞类型具有血液动力学优势,可产生最高的TAWSS和最低的OSI,RRT和ECAP平均值。此外,芭蕾舞类型的特点是DF最低,尽管观察到的差异很小,并且其临床相关性不确定。
    假定的流变模型对移植物的整体性能的影响并不显着。因此,相对安全的说法是,决定其整体性能的是支架移植物的类型,而不是所采用的血流模型。
    UNASSIGNED: To compare the hemodynamic performance of three (Bottom Up non-ballet, Top-Down non-ballet, Top Down ballet) idealized stent graft configurations used during endovascular repair of abdominal aortic aneurysms, under the influence of various rheological models.
    UNASSIGNED: Ten rheological models are assumed and a commercial finite volume solver is employed for the simulation of blood flow under realistic boundary conditions. An appropriate mesh convergence study is performed and five hemodynamic variables are computed: the time average wall shear stress (TAWSS), oscillatory shear index (OSI), relative residence time (RRT), endothelial cell activation potential (ECAP) and displacement force (DF) for all three configurations.
    UNASSIGNED: The choice of blood flow model may affect results, but does not constitute a significant determinant on the overall performance of the assumed stent grafts. On the contrary, stent graft geometry has a major effect. Specifically, the Bottom Up non-ballet type is characterized by the least favorable performance presenting the lowest TAWSS and the highest OSI, RRT and ECAP values. On the other hand, the Top Down ballet type presents hemodynamic advantages yielding the highest TAWSS and lowest OSI, RRT and ECAP average values. Furthermore, the ballet type is characterized by the lowest DF, although differences observed are small and their clinical relevance uncertain.
    UNASSIGNED: The effect of the assumed rheological model on the overall performance of the grafts is not significant. It is thus relatively safe to claim that it is the type of stent graft that determines its overall performance rather than the adopted blood flow model.
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