神经鞘瘤或神经鞘瘤包囊良好,良性,孤独,和起源于神经鞘的雪旺氏细胞的缓慢生长的肿瘤。据报道,颅外神经鞘瘤在舌头中的发病率相对较高,而在口底中的发病率极低。在目前的研究中,我们介绍了亚洲首例口底舌下神经源性神经鞘瘤。
对9例口底舌下神经源性神经鞘瘤手术病例进行回顾性研究。患者和肿瘤特征进行了身体检查,放射学和病理学检查。同时记录手术和并发症的细节。
口底的舌下神经源性神经鞘瘤显示出清晰的边界,质地坚硬,光滑的表面和良好的流动性在触诊。肿瘤的中位最大直径为4.3cm(范围2.8-7.0cm)。中位手术时间和出血量分别为89.4分钟(范围47-180分钟)和99.2mL(范围15-200mL),分别。所有病例均接受完整的手术切除。
在这项研究中,我们首次在亚洲介绍了舌下神经源性口底神经鞘瘤的诊断和治疗。该研究为我们提供了建议,当患者出现口腔底部肿块时,考虑诊断舌下神经鞘瘤。
Schwannomas or neurilemmomas are well-encapsulated, benign, solitary, and slow-growing tumors that originate from Schwann cells of the nerve sheath. Extracranial schwannoma is reported to have a relatively high incidence in the tongue while an extremely low incidence in the floor of mouth. In the current study, we presented the first
case series of hypoglossal nerve-derived schwannoma in the floor of mouth in Asia.
A retrospective study of 9 surgical cases of hypoglossal nerve-derived schwannoma in the floor of mouth was performed. The patient and tumor characteristics were evaluated by physical, radiological and pathological examination. Details of operation and complications were also recorded.
Hypoglossal nerve-derived schwannoma in the floor of mouth showed a well-defined boundary with a firm texture, smooth surface and good mobility on palpation. The median maximum diameter of the tumors was 4.3 cm (range 2.8-7.0 cm). The median operative time and bleeding volumes were 89.4 min (range 47-180 min) and 99.2 mL (range 15-200 mL), respectively. All cases received complete surgical excision.
In this study, we presented the diagnosis and management of hypoglossal nerve-derived schwannoma in the floor of mouth for the first time in Asia. The study provided us with a recommendation for consideration of the diagnosis of hypoglossal schwannoma when a patient presents with a mass in the floor of mouth.