目的：高危型人乳头瘤病毒（hrHPV）持续感染与大多数宫颈癌相关。本研究旨在调查山西省农村地区妇女hrHPV感染的患病率及其独立危险因素。中国。
方法：回顾性收集山西省农村妇女宫颈癌筛查记录资料。纳入2014年1月至2019年12月接受初次HPV筛查的女性。计算hrHPV的检出率,采用多因素logistic回归分析hrHPV感染的独立危险因素。
结果：在包括的女性中，hrHPV的总感染率为14.01%(15,605/111,353),前五名亚型是HPV16（24.79％），HPV52（14.04%），HPV58（10.26%），HPV18（7.25%），和HPV53（5.00%）。hrHPV感染的独立危险因素是特定的地理区域。测试年,年龄较大,教育水平较低,先前的筛查不足，细菌性阴道病,滴虫性阴道炎,还有宫颈息肉.
结论：40岁以上的农村妇女，尤其是那些从未接受过筛查的人，hrHPV感染的风险显着增加，应成为宫颈癌筛查的重点目标人群。
Persistent high-risk human papillomavirus (hrHPV) infection is associated with most cervical cancers. This study aims to investigate the prevalence of and independent risk factors for hrHPV infection among women residing in rural areas of Shanxi Province, China.
Data from the records of the cervical cancer screening programs for rural women in Shanxi Province were retrospectively collected. Women receiving primary HPV screening between January 2014 and December 2019 were included. The detection rate of hrHPV was calculated, and the independent risk factors for hrHPV infection were analyzed by multivariate logistic regression.
Among the women included, the overall infection rate of hrHPV was 14.01% (15,605/111,353), with the top five subtypes being HPV16 (24.79%), HPV52 (14.04%), HPV58 (10.26%), HPV18 (7.25%), and HPV53 (5.00%). The independent risk factors for hrHPV infection were specific geographical regions, testing years, older age, lower education level, inadequate previous screening, bacterial vaginosis, trichomonas vaginitis, and cervical polyps.
Rural women over 40 years of age, especially those who had never received screening, have a significantly increased risk for hrHPV infection and should be the target population with priority in cervical cancer screening.
