Hartmann's procedure

哈特曼氏手术
  • 文章类型: Journal Article
    目的:直肠癌治疗中使用的外科手术方式可能会影响癌症复发。这项研究的目的是确定手术类型是否会影响直肠癌手术的肿瘤学结果。
    方法:我们从瑞典结直肠癌注册中心收集了2013年至2017年接受R0/R1手术的TNMI-III期直肠癌患者的数据。哈特曼手术(HP)后的结果,比较前切除术(AR)和腹会阴切除术(APR),并进行多变量Cox回归分析.研究的主要结果是局部复发率。次要结果是远处转移,无病生存率和5年总生存率以及局部复发的危险因素。
    结果:本研究共纳入4741例患者:614例接受HP,3075例接受AR,1052例接受APR。多变量Cox回归显示局部复发无差异,远处转移或无病生存。AR后总生存率更高(OR0.62,CI0.54-0.72)。局部复发的危险因素为术中肠穿孔(OR2.41,CI1.33-4.40),pT4肿瘤(OR1.93,CI1.11-3.4)和环状切缘阳性(OR5.62,CI3.28-9.61)。
    结论:这项全国性研究表明,手术类型不影响局部复发率或远处转移。在不适合进行修复手术的患者中,HP是一种可行的替代方案,其肿瘤结局与APR相似。
    OBJECTIVE: The type of surgical procedure used in rectal cancer treatment may affect cancer recurrence. The aim of this study was to determine whether the type of procedure influences oncological outcomes in rectal cancer surgery.
    METHODS: We gathered data from the Swedish Colorectal Cancer Registry regarding patients with TNM Stage I-III rectal cancer who underwent R0/R1 surgery from 2013 to 2017. The outcomes after Hartmann\'s procedure (HP), anterior resection (AR) and abdominoperineal resection (APR) were compared, and a multivariable Cox regression analysis was performed. The primary outcome of the study was the local recurrence rate. The secondary outcomes were distant metastasis, disease-free survival and overall survival at 5 years as well as risk factors for local recurrence.
    RESULTS: A total of 4741 patients were included in the study: 614 underwent HP, 3075 underwent AR and 1052 underwent APR. Multivariable Cox regression revealed no difference in local recurrence, distant metastasis or disease-free survival. Overall survival was higher following AR (OR 0.62, CI 0.54-0.72). Risk factors for local recurrence were intraoperative bowel perforation (OR 2.41, CI 1.33-4.40), a pT4 tumour (OR 1.93, CI 1.11-3.4) and a positive circumferential resection margin (OR 5.62, CI 3.28-9.61).
    CONCLUSIONS: This nationwide study showed that the type of procedure did not affect the local recurrence rate or distant metastasis. In patients who are unfit for restorative surgery, HP is a viable alternative with oncological outcomes similar to those of APR.
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  • 文章类型: Journal Article
    目的:关于Hartmann程序(HP)在直肠癌治疗中的应用程度一直存在争议。本研究旨在调查HP术后30天的发病率和死亡率。直肠癌前切除术(AR)和腹会阴切除术(APR)使用国家注册。
    方法:所有接受直肠癌手术的患者,肿瘤高度5-15厘米,在2010年至2017年之间,通过瑞典结直肠癌登记处进行了鉴定。
    结果:共包括8476例患者:1210例(14%)接受HP,5406(64%)AR和1860(22%)APR。与AR和APR相比,HP与腹腔感染风险增加相关(OR1.7,CI1.26-2.28,P=0.0004),而APR与总体并发症风险增加相关(OR1.18,CI1.01-1.40,P=0.040)。HP之间的再手术率和再入院率没有显着差异,AR和APR,手术类型不是30日死亡率的危险因素.对距肛门边缘5-7厘米的肿瘤患者进行的亚组分析发现,HP与并发症或30天死亡率的增加无关。
    结论:对于AR不适合的患者,HP是一种有效的替代方案,具有良好的预后。APR与最高的30天总体并发症发生率相关。
    OBJECTIVE: There is ongoing controversy regarding the extent to which Hartmann\'s procedure (HP) should be used in rectal cancer treatment. This study was designed to investigate 30-day postoperative morbidity and mortality following HP, anterior resection (AR) and abdominoperineal resection (APR) for rectal cancer using a national registry.
    METHODS: All patients operated for rectal cancer, tumour height 5-15 cm, between the years 2010 and 2017, were identified through the Swedish colorectal cancer registry.
    RESULTS: A total of 8476 patients were included: 1210 (14%) undergoing HP, 5406 (64%) AR and 1860 (22%) APR. HP was associated with an increased risk of intra-abdominal infection (OR 1.7, CI 1.26-2.28, P = 0.0004) compared to AR and APR, while APR was related to an increased risk of overall complications (OR 1.18, CI 1.01-1.40, P = 0.040). No significant difference was observed in the rate of reoperations and readmissions between HP, AR and APR, and type of surgical procedure was not a risk factor for 30-day mortality. Findings from a subgroup analysis of patients with a tumour 5-7 cm from the anal verge revealed that HP was not associated with increased risk for complications or 30-day mortality.
    CONCLUSIONS: For patients where AR is not appropriate HP is a valid alternative with a favourable outcome. APR was associated with the highest overall 30-day complication rate.
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  • 文章类型: Journal Article
    背景:本研究的目的是提出一项为期三年的随机对照试验,该试验比较了Hartmann手术(HP)与乙状结肠切除术和原发性吻合(有或没有功能性回肠造口术)(PA)的随机设计,以确定穿孔憩室炎合并化脓性或腹膜炎的最佳治疗策略。
    方法:前瞻性收集随机分组后的前12个月的数据,并回顾性收集长达36个月的数据。主要的长期终点是指数程序后36个月的无气孔率。次要结果是36个月时有造口的患者,造口逆转的百分比,相关的再干预措施,造口旁/切口疝发生率,住院天数总计,包括所有再次入院,无论其与干预措施的关系如何,总发病率和死亡率。
    结果:在最初的130名患者中,有119名完成了三年的随访,PA组57例(48%),HP组62例(52%)。与HP相比,接受PA的患者36个月的造口游离率显着更好(PA92%vsHP81%,危险比2.326[95%CI1.538-3.517];对数秩p<0·0001)。造口逆转率没有显着差异(PA31/40(78%)与HP45/61(74%),p=0.814)。总累积发病率(PA21/57(36%)与HP30/62(48%),p=0.266)和死亡率(PA6/57(11%)与HP7/62(11%),p=1.000)组间没有差异。然而,HP组发生造口旁疝更多(HP10/62(16%)vsPA1/57(2%),p=0.009),与HP组相比,PA组三年随访后的平均住院天数显着降低(PA14天(IQR9.5-22.5)与HP17天(IQR12.5-27.5)),p=0.025)。
    结论:长期结果表明,在血液动力学稳定的情况下,免疫功能正常的患者初次吻合优于Hartmann's手术治疗穿孔憩室炎的长期吻合率,总体住院和造口旁疝。
    BACKGROUND: The aim of the present study is to present the three years follow-up a randomised controlled trial that compared Hartmann\'s Procedure (HP) with sigmoidectomy with primary anastomosis (with or without defunctioning ileostomy) (PA) in a randomised design to determine the optimal treatment strategy for perforated diverticulitis with purulent or fecal peritonitis.
    METHODS: Data were prospectively gathered for the first 12 months after randomization and retrospectively collected up to 36 months. The primary long-term endpoint was stoma free rate 36 months after the index procedure. Secondary outcomes were patients with a stoma at 36 months, percentage of stoma reversals, related reinterventions, parastomal/incisional hernia rates, total in hospital days including all readmissions regardless their relation to the intervention, overall morbidity and mortality.
    RESULTS: Three years follow-up was completed in 119 of the originally 130 included patients, with 57 (48%) in the PA-group and 62 (52%) patients in the HP-group. 36 months stoma free rate was significantly better for patients undergoing PA compared with HP (PA 92% vs HP 81%, hazard ratio 2.326 [95% CI 1.538-3.517]; log-rank p < 0·0001). Stoma reversal rates did not significantly differ (PA 31/40(78%) versus HP 45/61(74%), p = 0.814). Overall cumulative morbidity (PA 21/57(36%) versus HP 30/62(48%), p = 0.266) and mortality (PA 6/57(11%) versus HP 7/62 (11%), p = 1.000) did not differ between groups. However, more parastomal hernias occurred in the HP-group (HP 10/62(16%) vs PA 1/57(2%), p = 0.009) and the mean total in hospital days after three years follow-up was significantly lower in the PA-group compared to the HP-group (PA 14 days (IQR 9.5-22.5) versus HP 17 days (IQR 12.5-27.5)), p = 0.025).
    CONCLUSIONS: Long-term results showed that in haemodynamically stable, immunocompetent patients primary anastomosis is superior to Hartmann\'s procedure as treatment for perforated diverticulitis with respect to long-term stoma free rate, overall hospitalization and parastomal hernias.
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  • 文章类型: Journal Article
    BACKGROUND: Laparoscopic Hartmann\'s reversal (LHR) has recently been reported to be safer and more feasible than open Hartmann\'s reversal (OHR); however, there is limited data on the outcomes of LHR compared with those of OHR from Asian countries. Therefore, we aimed to clarify the postoperative outcomes of LHR compared with OHR, and additionally compare the patient outcomes post-LHR according to the previous Hartmann\'s procedure (HP) approach.
    METHODS: Patients who underwent OHR and LHR between January 2006 and September 2020 in a single center in Japan, were retrospectively evaluated. Patient characteristics and perioperative data were collected from the medical and surgical records and assessed.
    RESULTS: Overall, 15 and 19 patients underwent OHR and LHR, respectively, between January 2006 and September 2020. LHR was associated with less blood loss (median: 15 mL vs 185 mL; P < .001) and shorter hospital stays (9 days vs 14 days; P = .023) than OHR. There was no significant difference in postoperative complications between LHR and OHR (26.3% vs 40.0%, P = .475). However, two severe anastomotic complications in LHR were observed in patients with the stump below the peritoneal reflection. No significant difference in outcomes was observed between LHR patients who underwent open and laparoscopic HP.
    CONCLUSIONS: LHR resulted in positive outcomes regarding estimated blood loss and postoperative hospitalization, compared with OHR. Although the postoperative complications between LHR and OHR were not significant, patients with the stump below the peritoneal reflection may be at a high risk of anastomotic complications.
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  • 文章类型: Journal Article
    UNASSIGNED: The aim of this study is to compare the short outcomes of two methods of sigmoid resection and primary anastomosis with sigmoid resection and end colostomy (Hartmann\'s procedure) for sigmoid volvulus.
    UNASSIGNED: This retrospective study included 102, of which 56 patients underwent end colostomy (Hartmann\'s procedure) and 46 patients underwent resection and primary anastomosis for sigmoid volvulus. The medical records of the patients were reviewed to evaluate the patients\' characteristics, operative data, short-term postoperative outcomes and mortality.
    UNASSIGNED: The mean age of patients in the groups of Hartmann\'s procedure and primary anastomosis were 68.23 ± 13.42 and 70.10 ± 12.71, respectively. From the 46 patients who had primary colorectal anastomosis, 2 patients (4.3%) suffered from anastomosis leakage, which was not significantly different. This study showed that anastomosis leakage, prolonged ileus, bleeding, surgical site infection and fascial dehiscence were not different between Hartmann\'s procedure and primary anastomosis, significantly, p < 0.05. Hospital stay in the Hartmann group was less than primary anastomosis group in the same admission, p = 0.04. The mortality rate was not statistically different among the two groups, p = 0.549.
    UNASSIGNED: Postoperative complications and mortality rate do not different among the two groups however, the duration of hospitalization was lesser in Hartmann\'s procedure group.
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  • 文章类型: Comparative Study
    BACKGROUND: A reversal of Hartmann\'s procedure can be performed using either a laparoscopic or open approach. However, laparoscopic reversal (LR) of Hartmann\'s procedure is challenging. This study was designed to compare the results between open and laparoscopic approaches.
    METHODS: This was a retrospective study of prospectively collected data. We analysed 29 patients who received Hartmann\'s reversal at Korea University Anam Hospital between April 2007 and September 2014. All patients underwent either LR (n = 17) or open reversal (OR, n = 12).
    RESULTS: Patient characteristics were similar between the LR and OR groups. There was also no difference in mean operation time (212.5 versus 251.8 min), diversion ileostomy, length of hospital stay, postoperative analgesic days, time to diet resumption (3.9 versus 6.2 days) or complication rate. Although the time to resuming a solid diet was not different between the two groups (P = 0.053), bowel movement occurred faster in LR patients (LR versus OR, 1.8 versus 2.8 days, P = 0.020). Patients in the LR group also had less blood loss during surgery (114.1 versus 594.2 mL, P = 0.026). There were no mortalities in this study.
    CONCLUSIONS: LR of Hartmann\'s procedure resulted in faster bowel function recovery than the open method. Laparoscopic approaches are feasible even for patients who received an open Hartmann\'s procedure.
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