目的:绘制用于预防接受抗肿瘤治疗的癌症患者手足综合征的局部干预措施图。
方法:这是根据PRISMA-ScR(范围审查的扩展)和JoannaBriggs研究所手册的建议进行的范围审查。搜索是在电子数据库中进行的CINAHL,科克伦中部,EMBASE,LILACS,LIVIVIVO,PubMed,Scopus,WebofScience;和灰色文献(谷歌学者,Pro-Quest)。
结果:检索结果为12,016个参考文献,最终样本由45个研究组成。总共确定了42项主题干预措施,包括:保湿面霜,皮质类固醇,酸,mapisal,水飞蓟素,还有指甲花.然而,尿素是引用最多的干预措施(62%)。至于干预措施的介绍,它们不同的面霜,软膏,凝胶,水胶体,汤剂,补丁,粉末,油,和肥皂。
结论:结果允许回顾局部干预措施,重点是尿素和保湿霜的使用。然而,本综述中确定的大多数干预措施都需要在未来的研究中进行评估,以便更好地了解其益处.
OBJECTIVE: To map topical interventions used to prevent hand-foot syndrome in cancer patients undergoing antineoplastic therapy.
METHODS: This is a scoping
review reported in accordance with the recommendations of PRISMA-ScR (extension for scoping
review) and the Joanna Briggs Institute Manual. The searches were carried out in the electronic databases CINAHL, Cochrane CENTRAL, EMBASE, LILACS, LIVIVO, PubMed, Scopus, Web of Science; and gray literature (Google Scholar, Pro-Quest).
RESULTS: The searches resulted in 12,016 references and the final sample consisted of 45 studies. A total of 42 topical interventions were identified, including: moisturizing creams, corticosteroids, acids, mapisal, silymarin, and henna. However, urea was the most cited intervention (62%). As for the presentations of the interventions, they varied among creams, ointments, gels, hydrocolloids, decoctions, patches, powders, oils, and soaps.
CONCLUSIONS: The results allowed reviewing topical interventions, with emphasis on the use of urea and moisturizing creams. However, most of the interventions identified in this
review require evaluation in future studies for better understanding of their benefits.