乙型肝炎病毒(HBV)的再激活并不少见。已知发生在免疫抑制治疗中。有几种病毒感染可以触发HBV再激活,例如人类免疫缺陷病毒(HIV)感染。然而,文献中没有报道由EB病毒(EBV)感染引发的HBV再激活病例。据我们所知,我们报道了文献中首例急性EB病毒(EBV)感染继发HBV再激活的病例。一名47岁的白种人男性,有远程解决的急性乙型肝炎病毒感染史,出现在我们医院,患有严重的急性肝炎,表现为上腹痛,黄疸,深色尿液,浅色凳子,高胆红素血症,和转氨酶在1000年代。最终,患者被诊断为急性EBV感染引发的HBV再激活.经过几天的支持治疗,他的肝功能恢复正常.他在肝病诊所进行了定期随访后出院。总之,EBV感染应被怀疑为HBV再激活的触发因素,特别是当排除常见病因时。
Reactivation ofHepatitis B virus (HBV) is not an uncommon condition. It is known to occur with immunosuppressive therapy. There are several viral infections that can trigger HBV reactivation, such as human immunodeficiency virus (HIV) infection. However, there is no reported
case of HBV reactivation triggered by Epstein-Barr virus (EBV) infection in the literature. To our knowledge, we report the first
case of reactivation of HBV secondary to acute Epstein-Barr virus (EBV) infection in the literature. A 47-year-old Caucasian male with a remote history of resolved acute Hepatitis B virus infection presented to our hospital with severe acute hepatitis, which manifested as epigastric pain, jaundice, dark urine, light-colored stools, hyperbilirubinemia, and transaminitis in the 1000s. Ultimately, the patient was diagnosed with reactivation of HBV triggered by acute EBV infection. After several days of supportive treatment, his hepatic function normalized. He was discharged with a scheduled follow-up at a hepatology clinic. In conclusion, EBV infection should be suspected as a trigger in cases with HBV reactivation, particularly when common etiologies are excluded.