磷脂酰乙醇(PEth)测试是一种相对较新的工具,用于检测和大致量化一个人在各种安全性中对酒精的使用,medical,和法律环境。对PEth的基本化学性质进行了解释,特别关注使其非常适合在这种情况下用作酒精生物标志物的因素。本文满足了文献综述的需要,该文献综述综合了Peth实验室的发现,并提出了最新的解释指南。几种乙醇生物标志物已用于检测或监测酒精使用,但具有显著的局限性。基于这篇综述,作者提出了三项评估PEth值的准则:轻度或无消耗(<20ng/mL),显著消耗(20-199ng/mL),和大量消耗(>200ng/mL)。这些准则在就业和安全环境中很重要,但也适用于各种活动,如酒精治疗计划,器官移植决定,和监测受损的医疗专业人员。
Testing for phosphatidylethanol (PEth) is a relatively new tool for detecting and grossly quantifying a person\'s use of alcohol in a variety of security, medical, and legal environments. The basic chemistry of PEth is explained with a particular focus on factors that make it highly suitable as a biomarker for alcohol use in such situations. This article meets the need for a literature review that synthesizes PEth laboratory findings and suggests updated
guidelines for interpretation. Several ethanol biomarkers have been used for detection or monitoring alcohol use but have significant limitations. Based on this review, the authors propose three
guidelines for evaluating PEth values: Light or no Consumption (<20 ng/mL), Significant Consumption (20-199 ng/mL), and Heavy Consumption (>200 ng/mL). These
guidelines are important in employment and security environments, but also have applicability in such diverse activities as alcohol treatment programs, organ transplant decisions, and monitoring impaired medical professionals.