越来越多的证据表明患者使用替代和补充药物。使用至少一种膳食补充剂的美国人口百分比从1988-1994年的42%增加到2003-2006年的53%。我们介绍了一个40多岁的亚洲女性的案例,以前没有精神病,在短暂的精神病发作后出现在急诊室,在这期间她自己截肢了她的指尖,使用多种维生素和草药补充剂包括人参后,桂元(中草药),虾青素,枸杞(中国水果),硒,看到了棕榈,葡萄籽提取物,柑橘生物类黄酮,叶黄素(zeaxantin),resvexatrol,太阳小球藻,螺旋藻粉,植物神经酰胺,植物雌激素,胰高血糖素,菠萝蛋白酶加,和美国蜂花粉。全面的实验室检查,药物筛选,影像学诊断均为阴性。生命体征稳定。除了截肢的指尖,她其余的体检并不显著。每天两次服用利培酮1毫克治疗后,她的精神状态显着改善,在为期五天的精神病住院期间。这种情况引起了人们的注意,补充剂有可能产生坦率的精神病,需要医生密切监测和研究。
There is rising evidence of patients\' use of alternative and complementary medicine. The percentage of the U.S. population who used at least one dietary supplement increased from 42% in 1988-1994 to 53% in 2003-2006. We present a
case of an Asian female in her 40s, with no previous psychiatric illness, who presented to the emergency room following a brief psychotic episode, during which she self-amputated the tips of her fingers, after using multivitamins and herbal supplements including
ginseng, gui yuan rou (Chinese herb), astaxanthin, goji (Chinese fruit), selenium, saw palmetto, grape seed extract, citrus bioflavanoid, lutein (zeaxantin), resvexatrol, sun chlorella, spirulina powder, phytoceramides, phytoestrogen, glucosatrin, bromelain plus, and American bee pollen. Comprehensive laboratory workup, drug screening, and diagnostic imaging were negative. Vital signs were stable. Other than the amputated finger tips, the remainder of her physical examination was unremarkable. Her mental status improved significantly after treatment with risperidone 1 mg twice daily, during a five-day psychiatric hospitalization. This
case draws attention to the fact that supplements have the potential of producing frank psychosis and require close monitoring and study by physicians.