有越来越多的普通人口的比例生存到老年患有严重的慢性疾病,多发病率,和残疾。虚弱前状态和虚弱综合征的患病率随着年龄的增长呈指数增长,并与更高的发病率相关。残疾,住院治疗,制度化,死亡率,和医疗保健资源的使用。脆弱代表着一个全球性问题,进行早期识别,评估,和治疗,以防止从功能下降到残疾和死亡的级联事件,老年医学和普通医学的挑战之一。心律失常在年龄增长时很常见,慢性病,和虚弱,包括广泛的节律和传导异常。然而,没有专门针对老年人和体弱者的心律失常管理的系统研究或建议,而在这些患者中,许多有效的抗心律失常疗法的摄取仍然是最慢的。这个欧洲心律协会(EHRA)的共识文件侧重于脆弱的生物学,常见的合并症,以及评估脆弱的方法,关于心律失常和传导疾病的具体问题,提供关于虚弱综合征患者心律失常管理的证据基础建议,并确定知识差距和未来研究方向。
There is an increasing proportion of the general population surviving to old age with significant chronic disease, multi-morbidity, and disability. The prevalence of pre-frail state and frailty syndrome increases exponentially with advancing age and is associated with greater morbidity, disability, hospitalization, institutionalization, mortality, and health care resource use. Frailty represents a global problem, making early identification, evaluation, and treatment to prevent the cascade of events leading from functional decline to disability and death, one of the challenges of geriatric and general medicine. Cardiac arrhythmias are common in advancing age, chronic illness, and frailty and include a broad spectrum of rhythm and conduction abnormalities. However, no systematic studies or recommendations on the management of arrhythmias are available specifically for the elderly and frail population, and the uptake of many effective antiarrhythmic therapies in these patients remains the slowest. This European Heart Rhythm Association (EHRA)
consensus document focuses on the biology of frailty, common comorbidities, and methods of assessing frailty, in respect to a specific issue of arrhythmias and conduction disease, provide evidence base advice on the management of arrhythmias in patients with frailty syndrome, and identifies knowledge gaps and directions for future research.