Food Handling

食品处理
  • 文章类型: Journal Article
    植物蛋白为动物蛋白提供可持续和营养的替代品,其技术功能属性影响产品质量和设计师食品开发。由于植物蛋白固有的复杂性,适当的提取和修饰对于有效利用它们至关重要。这篇综述强调了植物基蛋白质的新兴来源,以及用于预处理的技术的最新统计数据,提取,和修改。预处理,植物蛋白质的提取和修饰方法已被分类,已解决,并适当指出了此类方法的最新应用。此外,这项研究为新兴技术对植物蛋白复杂动力学的潜在影响提供了新的观点。对100篇文章(2018-2024)的全面审查表明,研究人员对研究新型植物蛋白及其使用方式产生了浓厚的兴趣;种子是蛋白质提取的主要来源,其次是豆类。副产品作为蛋白质来源的使用正在迅速增加,这是值得注意的。蛋白质研究仍然缺乏关于蛋白质分数的知识,抗营养素,和预处理。物理方法的使用及其与其他技术的结合正在增加,以有效且环保地提取和修饰植物蛋白。一些研究探讨了蛋白质变化对其功能和营养的影响,特别是目标是用具有改善或增强品质的植物蛋白代替成分。然而,下一步是研究复杂的修饰方法,以更深入地了解食品安全和毒性。
    Plant-based proteins offer sustainable and nutritious alternatives to animal proteins with their techno-functional attributes influencing product quality and designer food development. Due to the inherent complexities of plant proteins, proper extraction and modifications are vital for their effective utilization. This review highlights the emerging sources of plant-based proteins, and the recent statistics of the techniques employed for pretreatment, extraction, and modifications. The pretreatment, extraction and modification approach to modify plant proteins have been classified, addressed, and the recent applications of such methodologies are duly indicated. Furthermore, this study furnishes novel perspectives regarding the potential impacts of emerging technologies on the intricate dynamics of plant proteins. A thorough review of 100 articles (2018-2024) shows the researchers\' keen interest in investigating novel plant proteins and how they can be used; seeds being the main source for protein extraction, followed by legumes. Use of by-products as a protein source is increasing rapidly, which is noteworthy. Protein studies still lack knowledge on protein fraction, antinutrients, and pretreatments. The use of physical methods and their combination with other techniques are increasing for effective and environmentally friendly extraction and modification of plant proteins. Several studies explore the effect of protein changes on their function and nutrition, especially with a goal of replacing ingredients with plant proteins that have improved or enhanced qualities. However, the next step is to investigate the sophisticated modification methods for deeper insights into food safety and toxicity.
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  • 文章类型: Journal Article
    作为一种重要的水产食品,鱼糜产品因其独特的粘弹性和较高的营养价值而受到消费者的青睐。凝胶性能是衡量鱼糜产品质量的主要指标。鱼糜的凝胶化主要涉及分子内(构象变化)和分子间(化学力)变化。加工处理等因素,生鱼种类和外源添加剂影响鱼糜蛋白结构,化学力和内源性酶活性,这进一步影响鱼糜制品的凝胶特性。本文综述了鱼糜热诱导凝胶的机理,主要包括蛋白质通过各种化学作用力进行扩链和聚集,形成三维网络结构。此外,探讨了不同因素对鱼糜凝胶特性的影响机理及应用,为鱼类种类的选择提供参考,鱼糜制品凝胶过程中加热条件的控制,添加剂的选择等措施来提高凝胶性能。
    As an important aquatic prepared food, surimi products are favored by consumers due to their unique viscoelastic properties and high nutritional value. Gel properties are the main indicators to measure the quality of surimi products. The gelation of surimi mainly involves intramolecular (conformational change) and intermolecular (chemical force) changes. Factors such as processing treatments, raw fish species and exogenous additives affect surimi protein structure, chemical forces and endogenous enzyme activities, which further affect the gel properties of surimi products. This review focuses on the mechanism of surimi heat-induced gel, mainly including protein chain expansion and aggregation through various chemical forces to form a three-dimensional network structure. In addition, the mechanism and application of different factors on the gel properties of surimi were also discussed, providing a reference for the selection of fish species, the control of heating conditions in the gel process of surimi products, the selection of additives and other measures to improve the gel performance.
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  • 文章类型: Journal Article
    冷等离子体处理是食品加工和保鲜领域的一项创新技术。它主要用于使微生物和酶失活,而无需加热和化学添加剂;因此,它通常被称为“清洁和绿色”技术。然而,在冷等离子体加工过程中,由于等离子体反应性物质和食品成分之间的潜在化学相互作用,可能会出现食品质量和安全方面的挑战。这篇综述旨在巩固和讨论冷等离子体对主要食品的化学成分以及物理和功能特性的影响的数据,包括乳制品,肉,坚果,水果,蔬菜,和谷物。我们强调冷等离子体如何诱导关键食品成分的化学改性,比如水,蛋白质,脂质,碳水化合物,维生素,多酚,和挥发性有机化合物。此外,我们讨论颜色的变化,pH值,冷等离子体处理诱导的感官特性及其与化学修饰的相关性。目前的研究表明,冷等离子体中的活性氧和氮可以氧化蛋白质,脂质,与食物基质直接接触时的生物活性化合物。营养素和生物活性化合物的减少,包括多不饱和脂肪酸,糖,糖多酚,和维生素,在乳制品中观察到,蔬菜,水果,和冷等离子体处理后的饮料。此外,观察到结构变化以及挥发性和非挥发性氧化产物的产生,影响颜色,风味,和食品的质地。然而,对干食物的影响,如种子和坚果,相对不那么明显。总的来说,这篇评论突出了缺点,挑战,以及与食品加工中的冷等离子体处理相关的机会。
    Cold plasma treatment is an innovative technology in the food processing and preservation sectors. It is primarily employed to deactivate microorganisms and enzymes without heat and chemical additives; hence, it is often termed a \"clean and green\" technology. However, food quality and safety challenges may arise during cold plasma processing due to potential chemical interactions between the plasma reactive species and food components. This review aims to consolidate and discuss data on the impact of cold plasma on the chemical constituents and physical and functional properties of major food products, including dairy, meat, nuts, fruits, vegetables, and grains. We emphasize how cold plasma induces chemical modification of key food components, such as water, proteins, lipids, carbohydrates, vitamins, polyphenols, and volatile organic compounds. Additionally, we discuss changes in color, pH, and organoleptic properties induced by cold plasma treatment and their correlation with chemical modification. Current studies demonstrate that reactive oxygen and nitrogen species in cold plasma oxidize proteins, lipids, and bioactive compounds upon direct contact with the food matrix. Reductions in nutrients and bioactive compounds, including polyunsaturated fatty acids, sugars, polyphenols, and vitamins, have been observed in dairy products, vegetables, fruits, and beverages following cold plasma treatment. Furthermore, structural alterations and the generation of volatile and non-volatile oxidation products were observed, impacting the color, flavor, and texture of food products. However, the effects on dry foods, such as seeds and nuts, are comparatively less pronounced. Overall, this review highlights the drawbacks, challenges, and opportunities associated with cold plasma treatment in food processing.
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  • 文章类型: Journal Article
    Sakazakii是一种潜在的致病菌,对渗透胁迫和低aw具有抗性,并且能够在婴儿奶粉中保持干燥状态。它在环境中广泛存在,并存在于各种产品中。尽管病例发生率低,新生儿中40%至80%的高死亡率使其成为公共卫生关注的微生物。本研究对目前在各种食品基质中应用的Sakazakii的还原方法进行了比较评估,指示趋势和工艺优化的相关参数。进行了系统评价和荟萃分析,定性地确定灭活和控制的主要方法,定量评价治疗因素对还原反应的影响。分层聚类树状图得出了每种治疗效率的结论。对最近的研究趋势的回顾确定了对替代疗法的潜在使用的关注,大多数研究涉及非热方法和乳制品。使用随机效应荟萃分析,估计了4对数的汇总效应大小;然而,乳制品基质上的热方法和处理显示出更宽的分散性-τ2=8.1,而植物基质的τ2=4.5和生物膜的τ2=4.0。荟萃分析模型表明,化学物质浓度等因素,施加的能量,和处理时间对还原的影响比温度升高更显著。非热处理,与热量协同作用,发现对乳制品基质的处理是最有效的。
    Cronobacter sakazakii is a potentially pathogenic bacterium that is resistant to osmotic stress and low aw, and capable of persisting in a desiccated state in powdered infant milks. It is widespread in the environment and present in various products. Despite the low incidence of cases, its high mortality rates of 40 to 80 % amongst neonates make it a microorganism of public health interest. This current study performed a comparative assessment between current reduction methods applied for C. sakazakii in various food matrices, indicating tendencies and relevant parameters for process optimization. A systematic review and meta-analysis were conducted, qualitatively identifying the main methods of inactivation and control, and quantitatively evaluating the effect of treatment factors on the reduction response. Hierarchical clustering dendrograms led to conclusions on the efficiency of each treatment. Review of recent research trend identified a focus on the potential use of alternative treatments, with most studies related to non-thermal methods and dairy products. Using random-effects meta-analysis, a summary effect-size of 4-log was estimated; however, thermal methods and treatments on dairy matrices displayed wider dispersions - of τ2 = 8.1, compared with τ2 = 4.5 for vegetal matrices and τ2 = 4.0 for biofilms. Meta-analytical models indicated that factors such as chemical concentration, energy applied, and treatment time had a more significant impact on reduction than the increase in temperature. Non-thermal treatments, synergically associated with heat, and treatments on dairy matrices were found to be the most efficient.
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  • 文章类型: Journal Article
    背景:供体母乳(DHM)是高危婴儿的重要营养来源(例如,早产和低出生体重)。持有人巴氏灭菌法,DHM处理中的一个常见步骤,已知会部分改变DHM的组成;然而,对脂肪组成的影响在历史上是不一致的。
    目的:本范围综述旨在广泛回顾有关Holder巴氏灭菌对DHM中脂肪含量影响的文献,专注于分析前样品混合。
    方法:对原始,同行评审的研究文章于7月11日进行,2022年。如果他们比较了匹配的原始(对照)和Holder-巴氏灭菌的人乳样品并测量了总脂质,胆固醇,和个别类别的脂肪酸。文章审查和选择由两名独立审查人员进行。
    结果:搜索产生了26个原始结果,1978年至2022年间发表的同行评审研究文章。研究之间的总体方法差异很大。当研究方法描述任何用于收集生乳的混合时,6项研究中的1项(17%)报告了巴氏灭菌后总脂肪浓度的小变化(<5%)。或者,在没有描述混合原奶以确保代表性样本的方法的研究中,18人中有10人(56%)报告了总脂肪浓度的显著变化(≥±5%),变化范围从-28.6%到+19.4%。
    结论:这篇综述表明,关于Holder巴氏灭菌对脂肪的影响的不一致发现可能与研究方法有关。特别是分析前样品混合。需要进行更多的研究来考虑分析前处理程序和方法的作用,以帮助阐明Holder巴氏灭菌对人乳成分的影响。
    Donor human milk (DHM) is an essential source of nutrition among high-risk infants (e.g., premature and low-birth weight). Holder pasteurization, a common step in DHM processing, is known to partially alter the composition of DHM; however, the impact on fat composition is historically inconsistent.
    This scoping review aimed to broadly review the literature on the impact of Holder pasteurization on the fat content in DHM, with a focus on preanalytical sample mixing.
    A systematic search of original, peer-reviewed research articles was conducted on 11 July, 2022. Articles were included if they compared matched raw (control) and Holder-pasteurized human milk samples and measured total lipids, cholesterol, and individual classes of fatty acids. Article review and selection was conducted by 2 independent reviewers.
    The search yielded 26 original, peer-reviewed research articles published between 1978 and 2022. Overall methodology varied considerably between studies. When study methods described any mixing for collecting raw milk, 1 (17%) of the 6 of studies reported a small change in total fat concentration following pasteurization (<5%). Alternatively, among studies that did not describe methods for mixing raw milk to ensure a representative sample, 10 (56%) of the 18 reported a significant change (≥± 5%) in total fat concentration, with changes ranging from -28.6% to +19.4%.
    This review suggests that inconsistent findings regarding the impact of Holder pasteurization on fat may be related to study methodologies, particularly preanalytical sample mixing. More research considering the role of preanalytical handling procedures and methodologies is necessary to help clarify the impact of Holder pasteurization on human milk composition.
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  • 文章类型: Journal Article
    超加工食品(UPFs)是工业加工的食品,通常是预先包装的,方便,能量密集,营养贫乏。UPFs在当前的西方饮食中很普遍,许多研究支持了它们对肥胖和心血管疾病等非传染性疾病的贡献。假设UPFs以多种方式影响身体,包括通过诱导肠道微生物组的变化。本文综述了关于UPFs对肠道微生物组影响的现有研究。我们还回顾了NOVA食品分类系统在随机对照试验和观察性研究中的当前使用情况,以及其实施对UPF研究的影响。尽管研究之间的方法存在一些差异,结果通常将UPF消费与许多负面健康后果联系起来。有人试图标准化UPF分类系统;然而,达成和执行共识是困难的。未来的研究集中在UPFs影响身体的机制上,包括通过微生物组和代谢组,对于完善我们对UPFs对人类健康影响的理解至关重要。
    Ultra-processed foods (UPFs) are foods that are industrially processed and are often pre-packaged, convenient, energy-dense, and nutrient-poor. UPFs are widespread in the current Western diet and their proposed contribution to non-communicable diseases such as obesity and cardiovascular disease is supported by numerous studies. UPFs are hypothesized to affect the body in multiple ways, including by inducing changes in the gut microbiome. This review summarizes the available research on the effect of UPFs on the gut microbiome. We also review current usage of the NOVA food classification system in randomized controlled trials and observational studies and how its implementation effects UPF research. Despite some differences in methodology between studies, results often associate UPF consumption with a number of negative health consequences. There are attempts to standardize a UPF classification system; however, reaching and implementing a consensus is difficult. Future studies focusing on the mechanisms by which UPFs effect the body, including through the microbiome and metabolome, will be essential to refine our understanding of the effects of UPFs on human health.
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  • 文章类型: Journal Article
    如今,由于全球变暖的同时加剧,食品工业正面临挑战,人口,和食物消费。作为合成生物学与食品科学的结合,为了解决这些问题,新型合成食品得到了高度的关注。然而,这些新颖的食物可能会引起与人类健康有关的潜在风险。四种新型合成食品,包括植物性食品,养殖肉,发酵食品,和以微藻为基础的食物,在研究中进行了综述。原始食物来源,消费者接受度,这些食物的优点和缺点进行了讨论。此外,潜在风险因素,比如营养,生物,和化学危险因素,对与这些食物相关的食物进行了描述和分析。此外,当前的检测方法(例如,酶联免疫吸附测定,生物传感器,色谱,聚合酶链反应,等温扩增,和微流体技术)和处理技术(例如,微波处理,欧姆加热,蒸汽爆炸,高静水压力,超声,冷等离子体,和超临界二氧化碳)进行了严格的审查和讨论。尽管如此,继续创新和开发新的检测和加工技术,以有效评估这些新型合成食品并确保其安全至关重要。最后,简要介绍了提高这些食品质量的方法。它将为食品工业中新型合成食品的开发和管理提供见解。
    Nowadays, the food industry is facing challenges due to the simultaneous rise in global warming, population, and food consumption. As the integration of synthetic biology and food science, novel synthetic foods have obtained high attention to address these issues. However, these novel foods may cause potential risks related to human health. Four types of novel synthetic foods, including plant-based foods, cultured meat, fermented foods, and microalgae-based foods, were reviewed in the study. The original food sources, consumer acceptance, advantages and disadvantages of these foods were discussed. Furthermore, potential risk factors, such as nutritional, biological, and chemical risk factors, associated with these foods were described and analyzed. Additionally, the current detection methods (e.g., enzyme-linked immunosorbent assay, biosensors, chromatography, polymerase chain reaction, isothermal amplification, and microfluidic technology) and processing technologies (e.g., microwave treatment, ohmic heating, steam explosion, high hydrostatic pressure, ultrasound, cold plasma, and supercritical carbon dioxide) were reviewed and discussed critically. Nonetheless, it is crucial to continue innovating and developing new detection and processing technologies to effectively evaluate these novel synthetic foods and ensure their safety. Finally, approaches to enhance the quality of these foods were briefly presented. It will provide insights into the development and management of novel synthetic foods for food industry.
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  • 文章类型: Journal Article
    毛孔和气泡显著影响物理属性(如纹理,密度,和结构完整性),感官特性,和加工食品的保质期。因此,食品的质量和消费者对其的接受程度可能受到食品结构中毛孔和气泡的性质和普遍性的影响。考虑到毛孔的重要性,本文旨在全面讨论不同食品加工过程中毛孔和气泡产生的因素和机制。此外,毛孔对巧克力特性的影响,奶酪,谷类食品(如蛋糕,膨化的谷物,和面食),干,和油炸产品进行了讨论。气泡对泡沫基产品质量的影响,泡沫奶精,和饮料也被探索。这篇综述得出结论,内在因素(如食物成分,初始含水率,和孔隙率)和外在因素(如应用技术,processing,和储存条件)影响孔隙和气泡的各种特性,包括它们的数量,尺寸,定位,和分配。这些因素共同塑造了加工食品的整体结构和质量,例如密度,质地(硬度,凝聚力,咀嚼性),和持水能力。孔及其特性的可取性或不可取性取决于产品的类型;因此,提供了一些实用的提示,以减轻其不利影响或增强其在食品中的形成。例如,毛孔可以通过增加脂肪氧化和微生物生长的风险来增加营养消化并缩短产品的保质期。总之,这项研究通过讨论毛孔对食品保存的影响,为食品科学家和行业专业人士提供了宝贵的资源,热,和传质(包括氧气,水分,口味,和营养)。了解加工过程中孔隙率的动态变化将有效地定制具有所需属性的最终产品质量,确保为特定应用量身定制的结果。
    Pores and bubbles significantly influence the physical attributes (like texture, density, and structural integrity), organoleptic properties, and shelf life of processed foods. Hence, the quality of foods and their acceptance by the consumers could be influenced by the properties and prevalence of pores and bubbles within the food structure. Considering the importance of pores, this review aimed to comprehensively discuss the factors and mechanisms involved in the generation of pores and bubbles during the processing of different food products. Moreover, the characteristics and effects of pores on the properties of chocolates, cheeses, cereal-based foods (like cake, puffed grains, and pasta), dried, and fried products were discussed. The impacts of bubbles on the quality of foam-based products, foam creamers, and beverages were also explored. This review concludes that intrinsic factors (like food compositions, initial moisture content, and porosity) and extrinsic factors (like applied technologies, processing, and storage conditions) affect various properties of the pores and bubbles including their number, size, orientation, and distribution. These factors collectively shape the overall structure and quality of processed food products such as density, texture (hardness, cohesiveness, chewiness), and water holding capacity. The desirability or undesirability of pores and their characteristics depends on the type of products; hence, some practical hints were provided to mitigate their adverse effects or to enhance their formation in foods. For example, pores could increase the nutrient digestion and reduce the shelf life of the products by enhancing the risk of fat oxidation and microbial growth. In conclusion, this study provides a valuable resource for food scientists and industry professionals by discussing the effects of pores on food preservation, heat, and mass transfer (including oxygen, moisture, flavors, and nutrients). Understanding the dynamic changes in porosity during processing will be effective in customization of final product quality with desired attributes, ensuring tailored outcomes for specific applications.
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  • 文章类型: Journal Article
    大米(OryzasativaL.)是消耗最多的谷物之一,其与几种重要的营养成分一起通常提供人类超过21%的热量需求。黄曲霉毒素(AFs)是谷物中普遍存在的几种曲霉属物种的有毒次级代谢产物,包括大米。这篇综述全面概述了生产要素,患病率,法规,检测方法,以及水稻生产链中AFs的去污策略。非洲和亚洲的水稻中AFs的流行比欧洲国家更为突出。发达国家对水稻AFs的规定比发展中国家更严格。稻米中AFs的污染水平在稻米生产链的不同阶段有所不同,并受生产实践的影响,包括温度在内的环境条件,湿度,湿度水分,水活动以及去皮等碾磨作业,parboiling,和抛光。一系列的方法,包括色谱技术,免疫化学方法,并开发了分光光度法,用于监测水稻中的AFs。色谱方法是最常用的AFs检测方法,其次是免疫化学技术。世界范围内采用的AFs净化策略涉及各种物理,化学,和生物学策略,甚至使用植物材料。总之,采用良好的农业实践,实施有效的AF检测方法,制定创新的黄曲霉毒素净化策略对于确保消费者大米的安全和质量至关重要。
    Rice (Oryza sativa L.) is one of the most consumed cereals that along with several important nutritional constituents typically provide more than 21% of the caloric requirements of human beings. Aflatoxins (AFs) are toxic secondary metabolites of several Aspergillus species that are prevalent in cereals, including rice. This review provides a comprehensive overview on production factors, prevalence, regulations, detection methods, and decontamination strategies for AFs in the rice production chain. The prevalence of AFs in rice is more prominent in African and Asian than in European countries. Developed nations have more stringent regulations for AFs in rice than in the developing world. The contamination level of AFs in the rice varied at different stages of rice production chain and is affected by production practices, environmental conditions comprising temperature, humidity, moisture, and water activity as well as milling operations such as de-husking, parboiling, and polishing. A range of methods including chromatographic techniques, immunochemical methods, and spectrophotometric methods have been developed, and used for monitoring AFs in rice. Chromatographic methods are the most used methods of AFs detection followed by immunochemical techniques. AFs decontamination strategies adopted worldwide involve various physical, chemical, and biological strategies, and even using plant materials. In conclusion, adopting good agricultural practices, implementing efficient AFs detection methods, and developing innovative aflatoxin decontamination strategies are imperative to ensure the safety and quality of rice for consumers.
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  • 文章类型: Systematic Review
    目的:鉴于妊娠期间不良结局的发生率增加,我们的研究小组进行了剂量反应系统评价和荟萃分析,以调查超加工食品(UPFs)消费与常见不良妊娠结局之间的关系,包括妊娠期糖尿病(GDM),先兆子痫(PE),早产(PTB),低出生体重(LBW),和小于胎龄儿(SGA)。UPFs被描述为通常通过化学过程修饰的食品物质的配方,然后使用香料组装成即食的超可口食品和饮料产品,颜色,乳化剂,和其他化妆品添加剂。例子包括咸味小吃,重组肉制品,已经制作的冷冻食品,和软饮料。
    方法:使用Scopus进行了全面搜索,PubMed,和截至2023年12月的WebofScience数据库。我们使用随机效应模型汇总了相对风险(RR)和95%置信区间(CI)。
    结果:我们的分析(包括54项涉及552,686个人的研究)显示,UPFs的摄入量与GDM风险增加之间存在显着关联(RR=1.19;95%CI:1.10,1.27;I2=77.5%;p<0.001;研究=44;参与者人数=180,824),PE(RR=1.28;95%CI:1.03,1.59;I2=80.0%;p=0.025;研究=12;参与者人数=54,955),虽然没有发现PTB的显著关系,LBW和SGA婴儿。重要的是,UPFs摄入量增加100g与GDM风险增加27%相关(RR=1.27;95%CI:1.07,1.51;I2=81.0%;p=0.007;研究=9;参与者数量=39,812).非线性剂量反应分析进一步表明,UPFs摄入量与GDM风险之间的非线性关系P非线性=0.034,P-反应=0.034),尽管未观察到PE的这种关系(P非线性=0.696,P剂量反应=0.812)。
    结论:总之,怀孕前和怀孕期间,长期和过量摄入UPFs与GDM和PE风险增加相关.然而,进一步的观察研究,特别是在拥有精确UPFs消费测量工具的不同族裔群体中,对于更全面的理解至关重要。
    OBJECTIVE: Given the increasing incidence of negative outcomes during pregnancy, our research team conducted a dose-response systematic review and meta-analysis to investigate the relationship between ultra-processed foods (UPFs) consumption and common adverse pregnancy outcomes including gestational diabetes mellitus (GDM), preeclampsia (PE), preterm birth (PTB), low birth weight (LBW), and small for gestational age (SGA) infants. UPFs are described as formulations of food substances often modified by chemical processes and then assembled into ready-to-consume hyper-palatable food and drink products using flavors, colors, emulsifiers, and other cosmetic additives. Examples include savory snacks, reconstituted meat products, frozen meals that have already been made, and soft drinks.
    METHODS: A comprehensive search was performed using the Scopus, PubMed, and Web of Science databases up to December 2023. We pooled relative risk (RR) and 95% confidence intervals (CI) using a random-effects model.
    RESULTS: Our analysis (encompassing 54 studies with 552,686 individuals) revealed a significant association between UPFs intake and increased risks of GDM (RR = 1.19; 95% CI: 1.10, 1.27; I2 = 77.5%; p < 0.001; studies = 44; number of participants = 180,824), PE (RR = 1.28; 95% CI: 1.03, 1.59; I2 = 80.0%; p = 0.025; studies = 12; number of participants = 54,955), while no significant relationships were found for PTB, LBW and SGA infants. Importantly, a 100 g increment in UPFs intake was related to a 27% increase in GDM risk (RR = 1.27; 95% CI: 1.07, 1.51; I2 = 81.0%; p = 0.007; studies = 9; number of participants = 39,812). The non-linear dose-response analysis further indicated a positive, non-linear relationship between UPFs intake and GDM risk Pnonlinearity = 0.034, Pdose-response = 0.034), although no such relationship was observed for PE (Pnonlinearity = 0.696, Pdose-response = 0.812).
    CONCLUSIONS: In summary, both prior to and during pregnancy, chronic and excessive intake of UPFs is associated with an increased risk of GDM and PE. However, further observational studies, particularly among diverse ethnic groups with precise UPFs consumption measurement tools, are imperative for a more comprehensive understanding.
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