蜂胶是一种天然的蜜蜂产生的物质,具有抗菌作用,抗炎,和伤口愈合特性,含有叶子中的一些成分,植物的芽和树脂。几个世纪以来,它一直被用于各种健康益处。在这份手稿中,我们小组使用PubMed和Embase审查了蜂胶的辐射防护作用,我们的审查是根据PRISMA声明进行的。最后,这篇评论包括27篇文章,其中包括来自细胞研究的蜂胶的辐射防护作用(n=8),动物模型(n=14),和人体试验(n=5)。结果表明,科学文献中提取的蜂胶的剂型为蜂胶的乙醇提取物,蜂胶的水溶性衍生物,或胶囊。蜂胶的辐射防护性能的功效是从参考书目中提取的,作为该树脂混合物的几种化合物单独或协同是具有辐射防护作用的可能候选物。事实上,2011年之前的研究缺乏蜂胶的全面表征,由于不同批次蜂胶中活性化合物的可变性,并且仅限于分析技术。此外,在这份手稿中,我们选择的研究主要包括来自巴西的蜂胶类型,克罗地亚,埃及,欧洲国家,和那些在西班牙商业化的。它们均含有蜂胶的乙醇提取物(EEP),并受不同剂型的影响。EEP显示大量存在亲脂性生物活性化合物,如黄酮,黄酮醇,和黄烷酮。
Propolis is a natural bee-produced substance with antimicrobial, anti-inflammatory, and wound-healing properties, containing some components from the leaves, buds and resins of plants. It has been used for centuries for various health benefits. In this manuscript, our group reviewed the radioprotective effect of propolis using PubMed and Embase, and our
review was conducted according to the PRISMA statement. Finally, 27 articles were included in this
review, which includes the radioprotective effect of propolis from cell-based studies (n = 8), animal models (n = 14), and human trials (n = 5). Results reflected that the dosage forms of propolis extracted in the scientific literature were ethanolic extracts of propolis, a water-soluble derivate of propolis, or capsules. The efficacy of the radioprotective properties from propolis is extracted from the bibliography, as several compounds of this resinous mixture individually or synergistically are possible candidates that have the radioprotective effect. In fact, studies prior to 2011 lacked a comprehensive characterization of propolis due to the variability in active compounds among different batches of propolis and were limited to analytical techniques. Furthermore, in this manuscript, we have selected studies to include primarily propolis types from Brazil, Croatia, Egypt, European countries, and those commercialized in Spain. They all contained ethanolic extract of propolis (EEP) and were influenced by different dosage forms. EEP showed a significant presence of lipophilic bioactive compounds like flavones, flavonols, and
flavanones.