镁合金血管夹具有良好的生物降解性和生物相容性,提高了临床应用的方便性和安全性。然而,镁合金血管夹也有一些缺点,如不合理的结构设计和过快的退化速度。在这项研究中,通过有限元模拟软件(Abaqus)模拟了用可生物降解的镁合金(Mg-Zn-Nd-Zr和Mg-Zn-Nd)普通V型血管夹夹紧血管的过程。一种新型的血管夹,P型血管夹,通过仿真进行了分析和研究。通过有限元模拟分析了V型和P型镁合金血管夹的差异。此外,研究了Zr元素对P型血管夹力学性能和耐腐蚀性能的影响,以提高其机械稳定性。结果表明,在Mg-Zn-Nd-Zr合金V型血管夹闭合过程中,这个剪辑有一些问题,如血管应力分布不均,血管裂缝和应力集中。改进的P型血管夹闭合均匀,血管里没有缝隙,能有效避免应力集中。改进后的P型血管夹闭合良好,能有效避免应力集中。Mg-Zn-Nd-Zr合金P型夹的耐腐蚀性能优于Mg-Zn-Nd合金P型夹(第7天降解速率为2.02mm/y和2.61mm/y,分别)。Mg-Zn-Nd-Zr合金P型血管夹在第7天仍保持闭合,能满足临床应用的要求。
The Mg alloy vascular clip has biodegradability and good biocompatibility, which can improve the convenience and safety of clinical application. However, the Mg alloy vascular clip also has some disadvantages, such as an unreasonable structure design and a degradation rate which is too fast. In this
study, the process of clamping blood vessels with a biodegradable Mg alloy (Mg-Zn-Nd-Zr and Mg-Zn-Nd) general V-type vascular clip was simulated by finite element simulation software (Abaqus). A new type of vascular clip, the P-type vascular clip, was analyzed and investigated through simulation. The differences between Mg alloy vascular clips of V-type and P-type were analyzed by finite element simulation. In addition, the effects of Zr element on the mechanical properties and corrosion resistance of P-type vascular clips were also investigated to improve the mechanical stability. The results show that during the V-type vascular clip closure of Mg-Zn-Nd-Zr alloy, this clip has some problems, such as uneven distribution of blood vessel stress, crevices in blood vessels and stress concentration. The improved P-type vascular clip has uniform closure, and there is no gap in the blood vessel, which can effectively avoid stress concentration. The improved P-type vascular clip is well closed and can effectively avoid stress concentration. The corrosion resistance of the Mg-Zn-Nd-Zr alloy P-type clip was better than that of the Mg-Zn-Nd alloy P-type clip (degradation rate of 2.02 mm/y and 2.61 mm/y on the 7th day, respectively). Mg-Zn-Nd-Zr alloy The P-type vascular clip remained closed even on the 7th day, which could meet the requirements of clinical application.